Cough relieving and sore-throat relieving cataplasm and preparation method thereof

A formulation and coating technology, which is applied in the direction of pharmaceutical formulations, medical preparations with no active ingredients, medical preparations containing active ingredients, etc., can solve the problems of no external use of the two medicines, no pharyngitis and other problems, and achieve Convenient and comfortable application, good drug stability, and strong sustained-release effect

Inactive Publication Date: 2013-02-27
DONGGUAN MATHEMATICAL ENG ACAD OF CHINESE MEDICINE GUANGZHOU UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There is no report in the literature on the prescription of traditional Chinese medicine for treating pharyngitis wit

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Example Embodiment

[0029] Example 1

[0030] Take 10g of Qingtiankui and 4g of puffballs, crush them with a Chinese medicine high-speed pulverizer, pass through a 60-mesh sieve, and the sieving rate of the powder will reach more than 95%. Combine the powders, mix them, and place them in an ultrafine pulverizer to continue crushing. Mesh sieve, the sieving rate is more than 90%, and the medicinal powder is obtained for use.

[0031] Take 3g of carbomer, add 57ml of water and swell overnight to obtain 5% carbomer paste for use. Take the medicinal powder, add about 20ml of distilled water, stir well, add the carbomer paste, stir for 30 minutes at 300 rpm, as phase I, for use; take another 50ml of glycerol, add 0.3g of aluminum glycolate and 10g of sodium polyacrylate in turn, Stir while adding, stir at 400 rpm for 20 minutes after the addition, as phase II, for use; take 5g of polyvinylpyrrolidone, add 20ml of distilled water, fully dissolve it, add 0.3g of tartaric acid, 0.5g of ethyl paraben, and add...

Example Embodiment

[0033] Example 2

[0034] Take 5g of Qingtiankui and 3g of puffball, combine them with a Chinese medicine high-speed pulverizer, and pass through a 40-mesh sieve. The sieving rate of the powder is more than 95%. Continue to pulverize in an ultrafine pulverizer and pass through a 300-mesh sieve. If it reaches more than 95%, get medicinal powder for use.

[0035] Take 2g of carbomer, add 38ml of water and swell overnight to obtain 5% carbomer paste for use. Take the medicinal powder, add about 15ml of distilled water, stir well, add carbomer paste, 3g of silicon dioxide, stir for 20 minutes at 300 rpm, as phase I, for use; take another 20ml of glycerol, add 0.15g of aluminum glycolate, and polyglycolate in turn. Sodium acrylate 6g, stir while adding, stir at 300 rpm for 30 minutes after the addition, as phase II, for use; take 3g polyvinylpyrrolidone, 3g sodium carboxymethyl cellulose, add appropriate amount of distilled water 20ml, fully dissolve, add tartaric acid sequentially 0....

Example Embodiment

[0037] Example 3

[0038] Take 15g of Cynanchum sylvestris and 3g of puffball, add 200ml of water and soak for 30 minutes, then reflux for extraction for 1 hour, filter, add 150ml of water and reflux for extraction for 1.5 hours, filter, combine the filtrate, and concentrate under reduced pressure to a density of 1.20 at 60℃ Clean the cream and set aside.

[0039] Take 1.5g of carbomer, add extract clear ointment and swell overnight to obtain carbomer paste, add 2g of silicon dioxide and appropriate amount of water, stir for 15 minutes at 300 rpm, as phase I, for use; take another 18ml of glycerin, add glycerol in turn Aluminum 0.1g, sodium polyacrylate 4g, stir while adding, stir at 400 rpm for 20 minutes after the addition, as phase II, for use; take 2g polyvinylpyrrolidone, 1.5g sodium carboxymethyl cellulose, add 20ml distilled water, fully After dissolving, add 0.1 g of tartaric acid and 0.3 g of ethyl paraben in sequence, and stir while adding. After all the materials are ad...

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PUM

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Abstract

The present invention relates to the technical field of traditional Chinese medicine preparation, and provides a cough relieving and sore-throat relieving cataplasm and a preparation method thereof, wherein the cataplasm adopts ford nervilia leaf and puff-ball as raw materials, and is prepared by adopting a matrix formula and the preparation method provided by the present invention, the traditional Chinese medicine raw materials comprise, by weight, 5-15 parts of ford nervilia leaf and 3-10 parts of puff-ball, and the prepared cataplasm has characteristics of high drug loading, good drug stability, good stickiness, no skin residue, no irritation allergy on skin, convenient and comfortable applying, and the like, can be clinically applied on corresponding meridian points of human body, has functions of lung heat clearing, cough relieving and sore-throat relieving, and is provided for treatments of cough with lung heat, sore throat, and the like.

Description

technical field [0001] The patent of the present invention relates to a traditional Chinese medicine patch and a preparation method thereof, in particular to a traditional Chinese medicine patch for relieving cough and pharynx catarrh and a preparation method thereof for treating lung-heat cough, sore throat, and tonsillitis. Background technique [0002] Catapult is a kind of external plaster, which is a new dosage form of transdermal drug preparation. It refers to the preparation of medicinal material extracts, medicinal materials or chemical drugs mixed with a suitable hydrophilic matrix and coated on the backing material. Made plaster. The characteristics of transdermal drug delivery: (1) The transdermal drug delivery system can avoid the first-pass effect of the liver and the inactivation of drugs in the gastrointestinal tract, and the absorption of drugs is not affected by gastrointestinal factors. Reduce individual differences in medication. (2) Maintain a constant ...

Claims

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Application Information

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IPC IPC(8): A61K36/898A61K47/38A61K9/70A61P11/14A61P11/04
Inventor 谢友良蒋东旭易智彪詹丽玲王德杭赖小平
Owner DONGGUAN MATHEMATICAL ENG ACAD OF CHINESE MEDICINE GUANGZHOU UNIV OF CHINESE MEDICINE
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