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Composition capable of promoting differentiation of autologous preadipocytes and formation of lipid droplets and preparation method thereof

A pre-adipocyte and composition technology, which is applied in the directions of medical preparations, drug combinations, and pharmaceutical formulas containing active ingredients, can solve problems such as human body damage and human health hazards.

Active Publication Date: 2013-04-24
SHENZHEN GENE BIOLOGICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] However, whether it is to use minimally invasive injection or surgical operation to change the fullness of the breast, it needs to be invasive to the human body, and the long-term oral medicine will also cause health hazards to the human body.

Method used

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  • Composition capable of promoting differentiation of autologous preadipocytes and formation of lipid droplets and preparation method thereof
  • Composition capable of promoting differentiation of autologous preadipocytes and formation of lipid droplets and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0105]The total amount of raw materials is 100 kg. Among them, the materials of phase A: 2.0 kg of glycerin, 2.0 kg of butanediol, 2.0 kg of pomegranate extract, 1.0 kg of root extract of Polygonum cuspidatum and deionized water; the materials of phase B are: 6.0 kg of macadamia nut seed oil, polydimethylcyclo Siloxane 2.0 kg, Cetyl Alcohol 2.0 kg, Glyceryl Stearate 2.0 kg, Cocoa Grandiflora Seed Butter 1.0 kg, Indian Myrrh Resin Extract 1.0 kg, Behenic Acid 0.2 kg, Cetearyl Alcohol Ether-2 is 0.2 kg, steareth-21 is 0.5 kg, frankincense oil is 1.0 kg, tetrahydropiperine is 0.01 kg, tetrahydromethylpyrimidinecarboxylic acid is 0.005 kg, bioflavonoids is 0.1 kg, cholesterol 1.0 Kg; Phase C materials: 1.0 kg of yam root extract, 4.0 kg of butanediol; D phase materials: 1.0 kg of motherwort extract, 1.0 kg of Pueraria mirifica root extract, 1.0 kg of sausage tree fruit extract, methyl silanol Hydroxyproline aspartate 1.0 kg, Cimicifuga racemosa root extract 1.0 kg, sodium hyaluro...

Embodiment 2

[0114] The total amount of raw materials is 100 kg. Among them, the materials of phase A: 4 kg of glycerin, 4 kg of butylene glycol, 2.5 kg of pomegranate extract, 1.5 kg of root extract of Polygonum cuspidatum and deionized water; the materials of phase B are: 6.5 kg of macadamia nut seed oil, polydimethylcyclo Silicone 3.0 kg, Cetyl Alcohol 3.0 kg, Glyceryl Stearate 3.0 kg, Cocoa Grandiflora Seed Butter 2.0 kg, Indian Myrrh Resin Extract 2.0 kg, Behenic Acid 0.7 kg, Cetearyl Alcohol Ether-2 is 1.0 kg, steareth-21 is 0.8 kg, frankincense oil is 1.5 kg, tetrahydropiperine is 0.25 kg, tetrahydromethylpyrimidinecarboxylic acid is 0.05 kg, bioflavonoids is 0.6 kg, cholesterol 1.5 kg; Phase C materials are: 3.0 kg of yam root extract, 4.0 kg of butanediol; D phase materials: 2.0 kg of motherwort extract, 5.0 kg of Pueraria mirifica root extract, 6.0 kg of sausage tree fruit extract, methyl silanol Hydroxyproline Aspartate 1.0kg, Cimicifuga racemosa Root Extract 1.0kg, Sodium Hyal...

Embodiment 3

[0117] The total amount of raw materials is 100 kg. Among them, the materials of phase A: 2.5 kg of glycerin, 2.5 kg of butanediol, 2.5 kg of pomegranate extract, 1.4 kg of root extract of Polygonum cuspidatum and deionized water; the materials of phase B are: 6.5 kg of macadamia seed oil, polydimethylcyclo Silicone 3.0 kg, Cetyl Alcohol 2.2 kg, Glyceryl Stearate 3.0 kg, Cocoa Grandiflora Seed Butter 2.2 kg, Indian Myrrh Resin Extract 1.2 kg, Behenic Acid 0.3 kg, Cetearyl Alcohol Ether-2 is 0.3 kg, steareth-21 is 0.6 kg, frankincense oil is 1.2 kg, tetrahydropiperine is 0.05 kg, tetrahydromethylpyrimidinecarboxylic acid is 0.01 kg, bioflavonoids is 0.2 kg, cholesterol 1.2 Kg; Phase C materials: 2.5 kg of yam root extract, 4.5 kg of butanediol; D phase materials: 1.5 kg of motherwort extract, 2.0 kg of Pueraria mirifica root extract, 2.0 kg of sausage tree fruit extract, methyl silanol Hydroxyproline ester aspartate 1.0 kg, Cimicifuga racemosa root extract 0.8 kg, sodium hyalu...

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Abstract

The invention specifically discloses a composition capable of promoting differentiation of autologous preadipocytes and formation of lipid droplets and a preparation method thereof. A commiphora mukul resin extract and a recombinant human epidermal growth factor (rhEGF) are main components of the composition; and the content of the components are that the commiphora mukul resin extract is 1.0 to 3.0% and the recombinant human epidermal growth factor (rhEGF) accounts for 0.01 to 0.10%. According to the invention, the commiphora mukul resin extract and the recombinant human epidermal growth factor are organically combined together; on the one hand, differentiation of autologous preadipocytes is promoted by the recombinant human epidermal growth factor, on the other hand, activity of lipase in decomposition of fat is inhibited by the commiphora mukul resin extract, so formation and accumulation of lipid droplets are promoted, and thus, the volume of a breast can be effectively increased.

Description

technical field [0001] The invention relates to a composition for promoting the differentiation of autologous preadipocytes and the formation of lipid droplets. Background technique [0002] With the development of society and the improvement of economic conditions, many women who love beauty hope to have a more perfect body shape, posture and appearance, thus the breast enhancement underwear industry, breast enhancement cosmetics, breast augmentation or breast enhancement surgery have emerged. So far, breast augmentation or breast enhancement methods are mainly divided into three categories: non-surgical methods, minimally invasive injection methods, and plastic surgery methods. [0003] Non-surgical methods mainly involve oral medications. Hormonal drugs are taken orally to regulate human hormone levels, promote mammary gland development, and improve secondary features, but the effect is slow, and long-term use has large side effects, especially easily inducing or promoti...

Claims

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Application Information

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IPC IPC(8): A61K38/18A61K38/00A61P15/14A61K36/328
Inventor 杨平顺张泽奇李建超李利芳
Owner SHENZHEN GENE BIOLOGICAL TECH
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