Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Intelligent micro valve based on micro-fluidic chip and production method thereof

A microfluidic chip and intelligent technology, applied in chemical instruments and methods, valve devices, mechanical equipment, etc., can solve the problems of difficult chip integration, complex structure, large volume, etc., achieve good application prospects, reduce costs, Simple operation effect

Inactive Publication Date: 2013-04-24
SUZHOU WENHAO MICROFLUIDIC TECH CO LTD
View PDF5 Cites 7 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In terms of microvalve research, it is divided into active and passive valves according to whether there is a power drive mechanism. This type of microvalve can realize the opening / closing of the valve, has good braking performance and high airtightness, but the disadvantage is that the structure is complex, the volume is large, and it is difficult to realize the integration on the chip.
Passive valves do not require external dynamic braking, and rely on the pressure difference on both sides of the valve to realize the switch. Its volume is small, but it cannot actively open / close or switch the valve
[0004] However, it is difficult for conventional technologies to intelligently drive and control microfluidics in microchannels. Therefore, to drive and control microfluidics in microfluidic chips by controlling changes in surface wettability, a convenient, fast and efficient , low-cost microfluidic drive and control technology should be one of the research directions of microvalve on microfluidic chips, and there has been no substantial breakthrough yet

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Intelligent micro valve based on micro-fluidic chip and production method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] The microstructure and microchannel pattern of the two-layer chip of the microfluidic chip with controllable microfluidic flow are designed and drawn by computer-aided design software. The microstructure and microchannel of the two-layer polymethyl methacrylate (PMMA) chip were processed and prepared by the numerical control CNC system. The chips of each layer were cleaned with tap water and distilled water respectively, and the remaining fingerprints, oil stains and other stains on the surface of the chip were wiped with ethanol. On the double-sided adhesive film, the required microstructures and microchannels were processed with a cutting machine. The two-layer chip is carefully aligned, glued, and pressure-sealed to make a smart microvalve based on a microfluidic chip. Put the sample solution into the sample injection hole of the microfluidic chip, the solution enters the microchannel driven by the external peristaltic pump, and uses the external temperature control ...

Embodiment 2

[0025] The microstructure and microchannel graphics of the two-layer chip of the centrifugal microfluidic chip were designed and drawn by computer-aided design software. The microstructure and microchannel of the two-layer disc-shaped polycarbonate (PC) chip were processed and prepared by the numerical control CNC system. The chips of each layer were cleaned with tap water and distilled water respectively, and the remaining fingerprints, oil stains and other stains on the surface of the chip were wiped with ethanol. On the double-sided adhesive film, the required microstructures and microchannels were processed with a cutting machine. The two-layer chip is carefully aligned, glued, and pressure-sealed to make a smart microvalve based on a microfluidic chip. Put the sample solution into the sample injection hole of the microfluidic chip, the solution enters the microchannel driven by the external peristaltic pump, and uses the external temperature control system to control the ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to an intelligent micro valve based on a micro-fluidic chip and a production method thereof. Microstructures and micro-channels are arranged on the surface of the micro-fluidic chip, a hydrophilic / dehydrophilic gate controlled switch is arranged on a main micro-channel, the surfaces of the micro-channels are modified through thermo-responsive molecules, reversible changes of surface appearance and chemical construction of the micro-channels cause changes of surface invasion under stimulation of external field temperature, movement of micro-fluid on the surfaces of the micro-channels is controlled, and therefore the intelligent micro valve achieves control on micro-fluid flowing. The intelligent micro valve is mainly applied to the related fields such as electrophoretic separation, chromatographic separation and immunoassay, achieves intelligent driving and control on micro-fluid, greatly reduces micro-fluid driving and control cost, has the advantages of being portable, economical, fast and efficient, and is a novel analysis technique for micro-fluid driving and control.

Description

technical field [0001] The invention relates to an intelligent microvalve based on a microfluidic chip and a preparation method thereof. The surface of the microfluidic chip has microstructures and microchannels, and the main microchannel is provided with a hydrophilic / hydrophobic gating switch. The surface of the microchannel is modified. Under the stimulation of external temperature, the reversible change of the surface morphology and chemical configuration of the microchannel leads to the change of the surface wettability, and the movement of the liquid fluid on the surface of the microchannel is controlled, so as to realize the microfluidic The intelligent microvalve for flow control is mainly used in electrophoretic separation, chromatographic separation, immunoassay and other related fields. Background technique [0002] Innovative analysis and testing technology has played an extremely important role in promoting the development of science, technology and economy all ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): F16K99/00B01L3/00
Inventor 叶嘉明王晓东沙俊聂富强
Owner SUZHOU WENHAO MICROFLUIDIC TECH CO LTD
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com