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Pharmaceutical composition for treating hemorrhoid and use thereof

A composition and drug technology, applied in the field of medicine, can solve the problem of non-recurrence of hemorrhoids, and achieve the effect of improving compliance and short-term pain

Inactive Publication Date: 2013-05-01
INNER MONGOLIA MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] The present invention solves the pain problem before and after hemorrhoid surgery that has not been solved in the world at present, and the new special medicine of the present invention can cure hemorrhoids without recurrence

Method used

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  • Pharmaceutical composition for treating hemorrhoid and use thereof
  • Pharmaceutical composition for treating hemorrhoid and use thereof
  • Pharmaceutical composition for treating hemorrhoid and use thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0012] One, the preparation of the sodium salt of furan-sulfathiazole Schiff base

[0013] The preparation of the sodium salt of furan-sulfathiazole Schiffer base is divided into four steps:

[0014] (1) In a 10-liter reactor, pour into 5 liters of solvent chloroform (CHCl3), once pour into about 0.38 liters of equimolar ratio reaction solution furan 4 moles and N, about 0.308 liters of 4 moles of N dimethylformamide. Control the water temperature in the outer layer of the reaction kettle to be between 45 degrees and 50 degrees, open the nitrogen valve leading to the reaction kettle, press the mechanical stirring button of the reaction kettle at the same time, and continue stirring for 48 hours to obtain the intermediate product furfuraldehyde in equimolar ratio, and produce The rate is 70%.

[0015] (2) In a reactor of 800 liters, 128 moles and 32 kilograms of raw material drug powder sulfathiazole (ST) are dropped into, and the ratio of absolute anhydrous dimethyl sulfoxide...

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PUM

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Abstract

The invention discloses a pharmaceutical composition for treating hemorrhoid and a use thereof. The pharmaceutical composition for treating hemorrhoid comprises furan-sulfathiazole schiff base sodium salt. The pharmaceutical composition solves the problem of the pain before and after the haemorrhoid operation, reduces hemorrhoid recurrence, and has effects of relieving pain, diminishing inflammation, stopping bleeding, absorbing efflux from an affected part, healing an ulcer surface, treating decay and promoting tissue regeneration, and activating biological cells, has high biological activity and can prevent canceration.

Description

technical field [0001] The invention belongs to the technical field of medicine and relates to a pharmaceutical composition for treating hemorrhoids, in particular to a pharmaceutical composition containing furan-sulfathiazole schiff base sodium salt. Background technique [0002] At present, the incidence of hemorrhoids is relatively high at home and abroad. Ninety people out of one hundred have suffered from hemorrhoids. Anyone who has hemorrhoids knows the pain. It is uncomfortable to stand and sit, and it still hurts to lie on the stomach. At present, the methods for treating hemorrhoids at home and abroad are nothing more than two methods of medication and surgery. Although these two methods can be cured, the treatment process is extremely painful, and the most terrible thing is that after the cure, it will follow the diet. Seasonal changes or surgery did not clean up the ulcer surface leading to recurrence of hemorrhoids. This makes people feel headache about this di...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/635A61P9/14C07D417/12
Inventor 徐振林
Owner INNER MONGOLIA MEDICAL UNIV
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