Duck escherichia coli and application thereof

Abstract

The invention relates to duck escherichia coli with strong virulence and good immunogenicity; and the preservation number of the strain is CGMCC No.6831. The invention further provides a duplex inactivated vaccine which comprises vaccine adjuvant and antigen, wherein the antigen is the duck escherichia coli with preservation number of CGMCC No.6831 and riemerella anatipestifer with preservation number of CGMCC No.6832. The prepared duplex inactivated vaccine of the duck escherichia coli and the riemerella anatipestifer can prevent duck colibacillosis with characteristic pathological changes, such as cellulose exudative inflammation in the heart or the liver for causing duck escherichia coli septicemia, pericarditis or pleural adhesions as characteristics, and can prevent duck infectious serositis with neurological sign, fibrinous pericarditis, perihepatitis and air sacculitis as characteristics, so that excellent market promotion foreground is achieved.

Description

technical field [0001] The invention belongs to the technical field of veterinary biological products, and more specifically relates to a duck Escherichia coli and its application, that is, a strain that can cause characteristic lesions of duck Escherichia coli sepsis, such as cellulose exudative inflammation in the heart or liver, pericardium Bacteria and their application for meningitis or pleural adhesions. Background technique [0002] Duck colibacillosis is caused by pathogenic duck Escherichia coli, and its symptoms are often similar to the symptoms and lesions of Riemerella anatipestifer infection. The serotypes often isolated and identified by domestic teaching and research institutions are O1, O2, O3, O78 Wait. In recent years, with the rapid development of meat duck breeding in China, especially Shandong, Henan, Guangdong, Fujian, Guangxi and other provinces, the occurrence of colibacillosis is very frequent, which seriously endangers the further development of du...

AI Technical Summary

Problems solved by technology

[0003] At present, the harm of Riemerella anatipestifer to the aquaculture industry not only directly causes animal morbidity and death, but also indirect economic losses caused by reduced feed conversion rate and stunted growth of ducks infected with Riemerella anatipestifer. It is very serious. Riemerella anatipestifer is sensitive to some antibacterial drugs, but it is difficult to remove, especially after the bacteria invade the airbag, the drug is difficult to reach. The drug resistance rate is high and extensive, and at the same time, it causes certain problems such as drug residues

Images