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Oral care compositions for benefiting teeth

A technique for oral care and composition, which is applied in the field of oral care composition and can solve problems such as impractical attachment to teeth

Inactive Publication Date: 2013-05-01
UNILEVER NV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, this product does not adhere realistically to the teeth, so it should only be in contact with the teeth for a short time before being rinsed from the mouth in the rinse water

Method used

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  • Oral care compositions for benefiting teeth
  • Oral care compositions for benefiting teeth
  • Oral care compositions for benefiting teeth

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0087] A biphasic aqueous-based oral care composition beneficial to teeth and in accordance with the present invention is made by mixing the following ingredients under conditions of moderate shear, atmospheric pressure and ambient temperature. The resulting composition is suitable for use with a toothbrush and is non-gritty when combined in approximately equal amounts and produces an excellent ribbon when applied to a toothbrush. The combined composition, which results in the oral care composition of the present invention, has a consumer-acceptable taste profile.

[0088] Calcium phase:

[0089] Element weight percentage Sorbitol (70%) 20.0 water margin preservative 1.0 sodium monofluorophosphate 1.1 sweetener (artificial) 0.2 Calcium silicate* 20.0 Abrasive silica 6.0 Thickening Silica (Fumed Silica) 2.5 Calcium silicate coated titanium dioxide** 4.00 spices 0.9 Sodium carboxymethyl cellulose 0.6 ...

Embodiment 2

[0095] Enamel and dentin blocks (3 cm2) were polished with silicon carbide sandpaper (1200 grit) for approximately 5 min. Dentin blocks were etched with 36% phosphoric acid for 60 seconds, followed by water washing. The blocks were purchased from commercial suppliers.

[0096] A slurry (similar to that described in Example 1) comprising 20 wt% calcium silicate and 4 wt% composite particle active was added to the water balance to make the slurry. A sodium phosphate slurry was made by adding 20% ​​by weight sodium phosphate to the balance of water. The resulting slurry was homogenized for approximately 10 minutes using conventional stirring equipment to produce a homogeneous composition.

[0097] Pour the homogenized slurry into a petri dish. Use an amount sufficient to cover the surface of the block placed in the dish. The blocks were brushed with a toothbrush for 1 minute and incubated in the slurry for 1 minute. The blocks were then washed three times with distilled wate...

Embodiment 3

[0108] In order to study the whitening effect of the exemplary biphasic oral care composition of Example 1, the following in vitro tests were performed.

[0109] Human teeth were cleaned and divided into two groups (N=8). The composition of Example 1 was applied to clean tooth surfaces (Group I) using a cotton swab. After 30 minutes, the treated tooth was brushed for 1 minute with a slurry of commercially available toothpaste and water (e.g. toothpaste containing fluoride, 0.4% by weight sodium fluoride:water = 1:2) to clean the treated surface . The clean teeth were incubated in simulated oral fluid for approximately 2 hours. Fourteen cycles of the treatment described above were applied to the teeth. Create simulated oral care solutions by combining the following materials:

[0110] simulated oral fluid

[0111] Element quantity NaCl 16.07g NaHCO 3 0.7g KCl 0.448g K 2 HPO 3 *H 2 o 3.27g MgCl 2 *6H 2 o 0.622g 1M HCl ...

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Abstract

Oral care compositions with composite particle actives are described. The composite particle actives have a core and a coating whereby the coating interacts with phosphate ions to produce calcium and phosphate reaction products that are suitable to adhere to tooth enamel and / or dentin in order to improve the characteristics of teeth.

Description

field of invention [0001] The present invention relates to oral care compositions that benefit teeth. The present invention more particularly relates to oral care compositions that at least remineralize and whiten teeth by delivering a source of calcium and phosphate to a consumer's teeth, eg, at the time of brushing (ie, in situ). The composition is stable and comprises a composite particle active that interacts with the phosphate ion to produce an in situ reaction product of calcium and phosphate that adheres surprisingly well to the enamel to ensure excellent whitening results. Furthermore, the composition, such as a toothpaste or gel, maintains good taste, texture and viscosity properties and makes teeth less sensitive and has excellent gloss properties. The composition also produces excellent antimicrobial results in the consumer's mouth after application as well as immediate whitening benefits. Background of the invention [0002] Many of the products we consume have...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/04A61K8/19A61Q11/00A61K8/27A61K8/29
CPCA61K8/0241A61K8/19A61K8/29A61Q11/00A61K2800/651A61K2800/412A61K8/27A61K2800/61A61P1/02A61K8/24A61K8/25
Inventor Y.邓G.丁X.李
Owner UNILEVER NV