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Microcapsule preparation for normalizing stomach and tonifying spleen

A preparation and soybean protein technology, which is applied in the field of pharmaceutical composition and its preparation, can solve the problems of unfavorable development of traditional Chinese medicine preparations, single dosage form, unfavorable drug safety for pediatric patients, etc.

Active Publication Date: 2013-06-12
CP PHARMA QINGDAO CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, the commonly used prescriptions for the treatment of children's anorexia mostly include Uncaria and cicada slough. side effects, which is also detrimental to the safety of the drug in pediatric patients
And in the prior art, dosage forms such as oral liquid and syrup are mostly used, and the dosage form is relatively single, which is not conducive to the external development of traditional Chinese medicine preparations

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0010] Magnolia 600g, Chrysanthemum 600g, Citrus aurantium 800g, Coix Seed 800g, Rice Sprout 800g, Hawthorn 400g, Bamboo Leaf 600g, Licorice 1000g, Sucrose Powder 800g, Monoglyceride 2g, Sucrose Ester 0.5g, Maltodextrin 30g, Soy Protein 60g.

[0011] The preparation method is as follows: 1) Weigh Magnolia bark, chrysanthemum, citrus aurantium, coix seed, hawthorn, rice bud, pale bamboo leaf, licorice by weight and pulverize, soak, add 4 times of water and decocted for 3 times, 45min each time, Combine the decoction liquid, concentrate, add 70% ethanol to stand, filter, remove ethanol by rotary evaporation, and dry to obtain powder; 2) Weigh sucrose powder by weight, and mix with the powder obtained in 1); 3) Take 10 g of the powder obtained by mixing Add it to 50ml of 70% ethanol as a capsule core for later use; 4) Weigh monoglyceride, sucrose ester, maltodextrin, and soy protein by weight and dissolve it in 700ml of water for later use; 5) Slowly add the capsule core liquid o...

Embodiment 2

[0013] Magnolia 700g, Chrysanthemum 700g, Citrus aurantium 900g, Coix Seed 900g, Rice Sprout 900g, Hawthorn 500g, Bamboo Leaf 700g, Licorice 1100g, Sucrose Powder 900g, Monoglyceride 4g, Sucrose Ester 0.7g, Maltodextrin 45g, Soy Protein 60g.

[0014] The preparation method is as follows: 1) Weigh Magnolia bark, chrysanthemum, citrus aurantium, coix seed, hawthorn, rice bud, pale bamboo leaf, licorice by weight and pulverize, soak, add 5 times of water and decocted for 3 times, 45min each time, Combine the decoction liquid, concentrate, add 70% ethanol to stand, filter, remove ethanol by rotary evaporation, and dry to obtain powder; 2) Weigh sucrose powder by weight, and mix with the powder obtained in 1); 3) Take 10 g of the powder obtained by mixing Add it to 50ml of 70% ethanol as a capsule core for later use; 4) Weigh monoglyceride, sucrose ester, maltodextrin, and soy protein by weight and dissolve it in 700ml of water for later use; 5) Slowly add the capsule core liquid o...

Embodiment 3

[0016] Magnolia 650g, Chrysanthemum 650g, Citrus aurantium 850g, Coix Seed 850g, Rice Sprout 850g, Hawthorn 450g, Bamboo Leaf 650g, Licorice 1050g, Sucrose Powder 850g, Monoglyceride 3g, Sucrose Ester 0.6g, Maltodextrin 30g, Soy Protein 45g.

[0017] The preparation method is as follows: 1) Weigh Magnolia bark, chrysanthemum, citrus aurantium, coix seed, hawthorn, rice bud, pale bamboo leaf, licorice by weight and pulverize, soak, add 5 times of water and decocted for 3 times, 45min each time, Combine the decoction liquid, concentrate, add 70% ethanol to stand, filter, remove ethanol by rotary evaporation, and dry to obtain powder; 2) Weigh sucrose powder by weight, and mix with the powder obtained in 1); 3) Take 10 g of the powder obtained by mixing Add it to 50ml of 70% ethanol as a capsule core for later use; 4) Weigh monoglyceride, sucrose ester, maltodextrin, and soy protein by weight and dissolve it in 700ml of water for later use; 5) Slowly add the capsule core liquid o...

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Abstract

The invention provides a microcapsule preparation for treating splenic and gastric incoordination and anorexia. The medicine comprises officinal magnolia bark, chrysanthemum, fructus aurantii, semen coicis, fructus oryzae germinatus, hawthorn, lophatherum gracile, liquorice and sucrose powder; and a wall material comprises glycerol monostearate, sucrose ester, maltodextrin and soy protein.

Description

technical field [0001] The invention relates to a pharmaceutical composition and a preparation method thereof, in particular to a microcapsule preparation for treating anorexia and stomach and spleen and a preparation method thereof. Background technique [0002] Anorexia is a disease name of modern medicine, and its clinical manifestations are prolonged loss of appetite and food intake. Weakness of the spleen and stomach and disharmony between the spleen and stomach can cause anorexia, and the main clinical manifestations are loss of appetite and food intake for a long time. According to the clinical manifestations of anorexia, Sang Li et al. divided them into six types: 1. The spleen loses health and function, and the spleen is invigorated to help the movement, and the appetite is increased. , 3. Liver qi stagnation type, suitable for soothing the liver and regulating qi, invigorating the spleen and appetizing, 4. Food stagnation and internal resistance type, suitable for...

Claims

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Application Information

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IPC IPC(8): A61K36/8994A61K47/42A61K9/50A61P1/14
Inventor 王明刚任莉陈阳生
Owner CP PHARMA QINGDAO CO LTD
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