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Medicine composition for treating central nervous system diseases and preparation method and application thereof

A technology of the central nervous system and composition, applied in the directions of nervous system diseases, drug combinations, pharmaceutical formulations, etc., can solve problems such as insufficient clinical treatment effect, achieve obvious synergistic effect, superior treatment effect, and save the total amount of use. Effect

Active Publication Date: 2013-06-19
CHENGDU UNIV OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The purpose of the present invention is to solve the problem that the clinical treatment effect in the prior art is not obvious enough

Method used

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  • Medicine composition for treating central nervous system diseases and preparation method and application thereof
  • Medicine composition for treating central nervous system diseases and preparation method and application thereof
  • Medicine composition for treating central nervous system diseases and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] Take by weighing raw material ferulic acid 100g, baicalin 60g, ligustilide 30g, add auxiliary material starch 150g to granulate, magnesium stearate 5g, dextrin 150g, microcrystalline cellulose 150g, evenly make granule, compress tablet, obtain tablet.

Embodiment 2

[0022] Take by weighing raw material ferulic acid 120g, baicalin 70g, ligustilide 40g, add auxiliary material starch 180g granulation, magnesium stearate 5g, dextrin 160g, microcrystalline cellulose 160g, evenly make granule, tabletting, obtains tablet.

Embodiment 3

[0024] Take by weighing raw material ferulic acid 150g, baicalin 80g, ligustilide 40g, add auxiliary material starch 230g to granulate, magnesium stearate 6g, dextrin 200g, microcrystalline cellulose 200g, evenly make granule, tabletting, obtains tablet.

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PUM

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Abstract

The invention belongs to the technical field of traditional Chinese medicine, and particularly provides a medicine composition for treating central nervous system diseases. The medicine composition is prepared from the following bulk pharmaceutical chemicals in parts by weight: 10-30 parts of ferulic acid, 6-12 parts of baicalin and 3-5 parts of ligustilide. The invention also provides a preparation method and specific application of the medicine composition. Drug effect experiments prove that the medicine combination provided by the invention can effectively improve the cognitive function of dementia or cognitive disorder patients, improve behavioral abnormity, improve the life quality of patients, can effectively treat brain cell oxidation stress injury and microinflammation injury, and has good therapeutic effect on degenerative change of a central nervous system.

Description

technical field [0001] The invention relates to a pharmaceutical composition for treating diseases of the central nervous system, in particular to a pharmaceutical composition for treating and alleviating senile dementia, vascular dementia or mild cognitive impairment, its preparation method and application, and belongs to the traditional Chinese medicine technology field. Background technique [0002] Alzheimer's disease refers to the senile disease caused by a variety of reasons, with cognitive impairment as the main clinical manifestation, and is a clinical syndrome. In recent years, with the aging of the population in all countries in the world, the incidence of Alzheimer's disease has shown a sharp upward trend, and its death rate ranks fourth after heart disease, tumor and stroke. According to statistics, the prevalence rate is about 5% in the population over 60 years old in my country, about 6 million, and increases with age. The pathological changes of senile demen...

Claims

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Application Information

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IPC IPC(8): A61K31/7048A61K31/192A61K31/365A61P25/28
Inventor 徐世军代渊
Owner CHENGDU UNIV OF TRADITIONAL CHINESE MEDICINE
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