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Compounds having virus resistance and composition thereof

An antiviral effect and compound technology, applied in antiviral agents, medical preparations containing active ingredients, organic active ingredients, etc. and other problems to achieve the effect of prolonging the life extension rate, reducing the viral load and reducing the load

Active Publication Date: 2013-07-24
樊向德 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Due to the complex biological characteristics of the virus, the existing targeted drugs against the virus (for the structure of the virus, regulatory proteins and enzymes, etc.) Due to the multiple resistance of drugs, safe, effective and cheap antiviral drugs have not been developed so far

Method used

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  • Compounds having virus resistance and composition thereof
  • Compounds having virus resistance and composition thereof
  • Compounds having virus resistance and composition thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0101] Example 1: All 13 Compound Compositions

[0102] Compound 3 is 1g, Compound 1 is 0.2g; Compound 2 is 0.4g; Compound 4 is 0.2g; Compound 5 is 1.1g; Compound 6 is 0.8g; Compound 7 is 2.5g; Compound 8 is 0.4g; Compound 9 is 0.3g; 0.1g of compound 10; 0.6g of compound 11; 0.2g of compound 12; 0.3g of compound 13; capsules were prepared according to conventional methods.

Embodiment 2

[0103] Example 2: 5 ingredient composition:

[0104] Compounds 1, 2, 3, 8, 12: 1 g for compound 3; 0.3 g for compound 1; 0.7 g for compound 2; 1.3 g for compound 8; 0.1 g for compound 12;

Embodiment 3

[0105] Example 3: 2 ingredient composition:

[0106] Compounds 3 and 10; 1 g of compound 3 and 0.4 g of compound 10; prepared into dispersible tablets according to conventional methods.

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PUM

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Abstract

The invention discloses compounds having virus resistance and a composition thereof. The composition comprises one or more of the 13 compounds comprising 6'-O-caffeoyl deacetyl asperulosidic acid methyl ester. The compounds having virus resistance and the composition thereof can be extracted from plants and can also be prepared by synthesis. The composition comprising the compounds having virus resistance can prevent and treat viral infection-caused diseases such as influenza, myocarditis, conjunctivitis, viral pneumonia, encephalitis, leukemia, hepatitis B, hepatitis C, AIDS, genitourinary system infection, EB virus infection, human papillomavirus infection and cytomegalovirus infection. The composition can be prepared into an oral preparation, an injection, a spray, a subcutaneous injection and an anus suppository.

Description

technical field [0001] The present invention relates to compounds with antiviral effects and compositions thereof, in particular to traditional Chinese medicine components and compositions thereof for treating and preventing viral infectious diseases. Background technique [0002] Viral diseases not only endanger human health, but also threaten human survival. In the "Priority Projects for Disease Control in Developing Countries" jointly issued by WHO and other agencies, it pointed out four major challenges facing human health, the third of which is the pandemic of emerging viral diseases. [0003] Due to the complex biological characteristics of the virus, the existing targeted drugs against the virus (for the structure of the virus, regulatory proteins and enzymes, etc.) The multiple resistance of drugs has resulted in the development of safe, effective and cheap antiviral drugs so far. Therefore, finding effective new antiviral targets and opening up new avenues for tre...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/7048A61K31/216A61P31/12
Inventor 樊向德陈鸣珍
Owner 樊向德