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Preparation method of Wenxin Formulation

The technology of a composition and a traditional Chinese medicine is applied in the field of preparation of traditional Chinese medicine compositions, which can solve the problems such as the lack of a drug preparation process for Wenxin Fang, and achieve the effects of no toxic and side effects, definite curative effect and drug safety.

Active Publication Date: 2015-02-04
曹洪欣 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The purpose of the present invention is to solve the problem that the existing Wenxin prescription does not have a pharmaceutical preparation process for actual production, and provide a preparation method for Wenxin prescription

Method used

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  • Preparation method of Wenxin Formulation
  • Preparation method of Wenxin Formulation
  • Preparation method of Wenxin Formulation

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specific Embodiment approach 1

[0036] Specific embodiment one: the preparation method of Wenxin recipe in this embodiment is carried out according to the following steps:

[0037] 1. Take 8-12g white ginseng, 8-12g cassia twig, 13-17g melon wilt, 13-17g scallion, 8-12g Qingpinellia, 13-17g red peony root, 13-17g Ophiopogon japonicus and 3-7g coptis, Add 70% ethanol with a mass concentration of 8 times the total mass of the above drug, and then reflux extraction for 3 times, each time for 1 to 2 hours, combine the extracts and cool for 10 to 15 minutes, and then filter through 16 layers of gauze;

[0038] 2. Add 70% ethanol with a mass concentration of 8 times the total mass of the filter residue to the filter residue filtered in step 1, reflux extraction for 1 hour, and cool the extract for 10 to 15 minutes, then filter through 16 layers of gauze, and filter residue Add again 70% ethanol with a mass concentration of 8 times the mass of the filter residue, reflux extraction for 1 hour, combine all the filtra...

specific Embodiment approach 2

[0050] Specific embodiment two: the difference between this embodiment and specific embodiment one is: take 10g white ginseng, 10g cassia twig, 15g melon wilt, 15g scallion white, 10g Qingpinellia, 15g red peony root, 15g Radix Ophiopogon japonicus and 5g coptis. Other steps and parameters are the same as those in Embodiment 1.

specific Embodiment approach 3

[0051] Embodiment 3: The difference between this embodiment and Embodiment 1 or 2 is that in Step 1, the extracts are combined and cooled for 12 minutes. Other steps and parameters are the same as those in Embodiment 1 or Embodiment 2.

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Abstract

The invention discloses a preparation method of Wenxin Formulation, which relates to a preparation method of a traditional Chinese medicinal composition for treating the syndrome of heart-qi insufficiency and solves the problem in the prior art that there is no a pharmaceutical preparation process for Wenxin Formulation. The method comprises (1) taking white ginseng, cassia twig, Trichosanthes kirilowii, Allium macrostemon, Ternate pinellia, Paeonia lactiflora, Ophiopogon japonicas and Coptis chinensis, reflux-extracting with ethanol, and cooling and then filtering the extraction liquid; (2) adding ethanol into the extraction residues for reflux-extraction, cooling and then filtering the extraction liquid, adding ethanol into the extraction residues again for reflux-extraction, mixing all the filtrates, recovering the filtrates under reduced pressure, concentrating until no ethanol smell is detected, evaporate to dryness in an evaporating dish, and then vacuum-drying. The preparation method of Wenxin Formulation (a traditional Chinese medicinal composition for treating the syndrome of heart-qi insufficiency), disclosed in the invention, has a simple and convenient process, conforms to the requirements in real production, and solves the problem in the prior art that there is no a pharmaceutical preparation process for Wenxin Formulation. The prepared Wenxin Formulation has definite efficacy on the syndrome of heart-qi insufficiency, and the total effectiveness reaches 90.8%.

Description

technical field [0001] The invention relates to a preparation method of a traditional Chinese medicine composition for treating heart-qi deficiency. Background technique [0002] Wenxin prescription is composed of ginseng, cassia twig, melon, scallion, pinellia, red peony root, radix radices, and coptis. It is Professor Cao Hongxin's experience in treating heart-qi deficiency. The characteristics of pathogenesis, based on "Gualou Xiebai Banxia Decoction", after long-term clinical practice and a large number of experimental studies, it shows that it has a definite curative effect on heart-qi deficiency syndrome and heart-yang deficiency syndrome, with a total effective rate of 90.9%. . However, because it is a prescription with clinical experience, it lacks a drug preparation process and quality standards suitable for actual production, which restricts the establishment of a quality control evaluation system for Wenxin Fang and the need for industrial production. Contents ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8968A61P9/10A61P9/00
Inventor 曹洪欣王喜军韩莹孙晖张芳梅王芹芹张贺闫广利
Owner 曹洪欣
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