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Watermelon vine extract capable of treating diabetes as well as preparation method and application of watermelon vine extract

A technology of diabetes and watermelon vine, applied in the field of watermelon vine extract and its preparation, can solve the problems of research reports and patents on the composition of effective parts of watermelon vine diabetes that have not yet been seen

Inactive Publication Date: 2014-02-05
GUANGXI UNIV OF CHINESE MEDICINE +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

So far, there have been no research reports and patents on the composition of effective parts of watermelon vine for treating diabetes.

Method used

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  • Watermelon vine extract capable of treating diabetes as well as preparation method and application of watermelon vine extract
  • Watermelon vine extract capable of treating diabetes as well as preparation method and application of watermelon vine extract
  • Watermelon vine extract capable of treating diabetes as well as preparation method and application of watermelon vine extract

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Embodiment Construction

[0020] One, the preparation of watermelon vine extract

[0021] Such as figure 1 As shown, take 10kg of dried and pulverized watermelon vines, ultrasonicate for 2 hours with an ethanol solution with a volume concentration of 80% according to the weight to volume ratio of 5:1, then soak for 10 days, filter, combine the filtrates, concentrate under reduced pressure to obtain a dark green extract, and freeze Dry to get 300g green powder; disperse the green powder in 5000mL deionized water according to the weight-to-volume ratio of 3:50, let it stand overnight, and centrifuge (3000rpm·min -1 ) to separate the water-insoluble green viscous solid suspension and aqueous solution; take the aqueous solution and use 3 times the volume of petroleum ether extraction, ethyl acetate, and n-butanol to extract the sample successively, and the extract is concentrated under reduced pressure respectively, and the solvent is recovered and evaporated to dryness. Petroleum ether fraction (30 g), e...

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Abstract

The invention discloses a watermelon vine extract capable of treating diabetes as well as a preparation method and an application of the watermelon vine extract. The watermelon vine extract is prepared from ethyl acetate parts which are obtained by performing alcohol precipitation and water extraction on watermelon vines. The research shows that the watermelon vine extract has the good blood sugar decreasing activity, so that the watermelon vine extract can be applied to the clinical treatment of the diabetes comprising I-type diabetes and II-type diabetes. The abundant resources of the watermelon vines, namely crop wastes, are fully utilized, thereby providing a powerful theoretical foundation for deeply researching and developing the medicinal values and the clinical significances of the watermelon vines. As a result, a novel modern traditional Chinese medicine preparation with a good diabetes treating function for clinical applications is provided.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine extracts, and in particular relates to a watermelon vine extract capable of treating diabetes and its preparation method and application. Background technique [0002] According to the survey of the World Health Organization, the number of diabetic patients in the world is as high as 160 million, and there are more than 40 million diabetic patients in my country, accounting for about 1 / 4 of the global diabetes population. Up to 100,000 patients die from complications of diabetes every year, and the trend is increasing year by year. Diabetes has become a major killer that threatens human health. Therefore, the treatment and prevention of diabetes is particularly important. Diabetes is an endocrine disease and can be divided into type I and type II. Its etiology is complicated, and the pathogenesis and pathogenesis are not completely clear at present, and there is no special t...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/42A61P3/10A23L1/29A61K135/00A23L33/00
Inventor 邓家刚王硕龚小妹周小雷周丹丹戴航
Owner GUANGXI UNIV OF CHINESE MEDICINE
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