Pancreatic Cancer Detection Methods

A serial number and antibody technology, applied in chemical instruments and methods, biochemical equipment and methods, and microbial determination/examination, etc., can solve the problems of no report on the diagnosis of pancreatic cancer, no report on the expression of CAPRIN-1, etc.
CN103718045BActive Publication Date: 2016-08-17TORAY IND INC
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
TORAY IND INC
Publication Date
2016-08-17

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Abstract

The present invention relates to a method for detecting pancreatic cancer by using a new tumor marker. Specifically, the present invention provides a method for detecting pancreatic cancer, which includes determining the antibody that is directed against the CAPRIN‑1 protein through the antigen in a sample isolated from a subject. The antibody response has the presence or amount of bound reactive polypeptides and provides a reagent or kit for detecting pancreatic cancer comprising CAPRIN-1 protein or fragments thereof, antibodies directed thereto, or polynucleotides encoding them.
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Description

technical field

[0001] The invention relates to a method for detecting pancreatic cancer using CAPRIN-1 as a tumor marker. Background technique

[0002] Pancreatic cancer, one of the refractory cancers, is reported to have more than 10,000 patients in my country, and its incidence is increasing year by year, and it is expected to increase in the future. In the case of pancreatic cancer, even if surgery can be performed, since small cancers often invade and metastasize to other organs, pancreatic cancer often recurs, and the 5-year survival rate is 9%. The prognosis is very poor. In addition, gemcitabine, which is one of anticancer agents, is used for the purpose of preventing recurrence after surgery. However, the effect of gemcitabine administration is mainly analgesic, and its tumor shrinking effect and / or life prolonging effect cannot basically be expected. In addition, there are also hospitals using TS-1, an anticancer agent currently used in gastric cancer, but the si...

Claims

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