Gel for assisting swallow of oral solid medicinal preparation

A technology for solid pharmaceutical preparations and gels, which is applied to non-active medical preparations, pharmaceutical formulations, non-active components of polymer compounds, etc. Difficulty taking medication

Active Publication Date: 2014-04-16
江苏祈瑞医药有限公司
View PDF10 Cites 13 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Especially for the elderly and children, it will cause difficulty in taking medicine, low compliance, and failure to achieve therapeutic effect
[0003] CN101938992A discloses compositions and methods for assisting swallowing, said method comprising providing an at least partial surface covering comprising a lubricating edible gel composition on said article, said method and said gel composition being effective in taste-masking And although it has a certain effect in aid...

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Gel for assisting swallow of oral solid medicinal preparation
  • Gel for assisting swallow of oral solid medicinal preparation
  • Gel for assisting swallow of oral solid medicinal preparation

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018]

[0019] Add locust bean gum and carrageenan into water, heat to above 95°C, stir to dissolve, add flavoring agent, stir to dissolve. Pass through a 100-mesh sieve and cool. After testing, the prepared gel has a gel strength of 41g / cm at 20°C 2 , the pH value is 6.8, and the disintegration time limit in 0.1mol / L hydrochloric acid solution is 2 minutes.

Embodiment 2

[0021]

[0022]

[0023] Add carrageenan and guar gum into water, heat to above 60°C, stir to dissolve, add flavoring agent, stir to dissolve. Pass through a 100-mesh sieve and cool. After testing, the prepared gel has a gel strength of 25g / cm at 20°C 2 , the pH value is 6.3, and the disintegration time limit in 0.1mol / L hydrochloric acid solution is 4 minutes.

Embodiment 3

[0025]

[0026] Add pectin and carrageenan into water, heat to above 95°C, stir to dissolve, add flavoring agent, stir to dissolve. Pass through a 100-mesh sieve and cool. After testing, the gel strength of the prepared gel is 22g / cm2 at 20°C 2 , the pH value is 4.6, and the disintegration time limit in 0.1mol / L hydrochloric acid solution is 3 minutes.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

PropertyMeasurementUnit
Gel strengthaaaaaaaaaa
Gel strengthaaaaaaaaaa
Gel strengthaaaaaaaaaa
Login to view more

Abstract

The invention provides gel for assisting swallow of an oral solid medicinal preparation. The gel comprises the following components in percentage by weight: 0.1-0.5 percent of an acid-containing gel material for promoting disintegration, 0.1-5.0 percent of a gel material with lubricating and coating performance, 0.1-15.0 percent of a flavoring agent, and a proper amount of water. An oral solid medicinal preparation can be coated with the gel, so that the unpleasant taste of the medicine can be isolated, the smooth taste can be improved, the compliance of a patient can be improved, and a person with swallow difficulty can be assisted to take the medicine; and furthermore, the gel can be quickly disintegrated and dissolved in the body, so that the drug effect of the oral solid medicinal preparation in the body cannot be influenced.

Description

technical field [0001] The invention relates to a gel for helping to swallow oral solid pharmaceutical preparations. The gel can wrap the oral solid drug preparation, isolate the unpleasant taste of the drug and increase the smooth taste, improve the compliance of the drug taker, and help those who have difficulty swallowing the drug. At the same time, the gel disintegrates and dissolves quickly in the body, without Affect oral solid pharmaceutical preparations to exert their medicinal effects in vivo. Belongs to the field of medicine. Background technique [0002] Many oral pharmaceutical preparations have special tastes, such as pungent tastes such as bitterness, sourness, and pungentness, which are difficult for users to accept. The pharmaceutical preparations are swallowed directly with water without chewing, and there will be a foreign body sensation and discomfort in the throat. Especially for the elderly and children, it will cause difficulty in taking medicine, lo...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): A61K47/36A61K47/42A61K47/38
Inventor 尹国民邱瑞宝朱美霞张发明徐静芳戚文荣陶征宇邓钢吴明辉
Owner 江苏祈瑞医药有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap