Gel for assisting swallow of oral solid medicinal preparation

Abstract

The invention provides gel for assisting swallow of an oral solid medicinal preparation. The gel comprises the following components in percentage by weight: 0.1-0.5 percent of an acid-containing gel material for promoting disintegration, 0.1-5.0 percent of a gel material with lubricating and coating performance, 0.1-15.0 percent of a flavoring agent, and a proper amount of water. An oral solid medicinal preparation can be coated with the gel, so that the unpleasant taste of the medicine can be isolated, the smooth taste can be improved, the compliance of a patient can be improved, and a person with swallow difficulty can be assisted to take the medicine; and furthermore, the gel can be quickly disintegrated and dissolved in the body, so that the drug effect of the oral solid medicinal preparation in the body cannot be influenced.

Description

technical field [0001] The invention relates to a gel for helping to swallow oral solid pharmaceutical preparations. The gel can wrap the oral solid drug preparation, isolate the unpleasant taste of the drug and increase the smooth taste, improve the compliance of the drug taker, and help those who have difficulty swallowing the drug. At the same time, the gel disintegrates and dissolves quickly in the body, without Affect oral solid pharmaceutical preparations to exert their medicinal effects in vivo. Belongs to the field of medicine. Background technique [0002] Many oral pharmaceutical preparations have special tastes, such as pungent tastes such as bitterness, sourness, and pungentness, which are difficult for users to accept. The pharmaceutical preparations are swallowed directly with water without chewing, and there will be a foreign body sensation and discomfort in the throat. Especially for the elderly and children, it will cause difficulty in taking medicine, lo...

AI Technical Summary

Problems solved by technology

Especially for the elderly and children, it will cause difficulty in taking medicine, low compliance, and failure to achieve therapeutic effect

[0003] CN101938992A discloses compositions and methods for assisting swallowing, said method comprising providing an at least partial surface covering comprising a lubricating edible gel composition on said article, said method and said gel composition being effective in taste-masking And although it has a certain effect in aiding swallowing, when it is used to assist drug swallowing, the drug cannot be disintegrated or released normally because it is wrapped in gel, which seriously affects the release and absorption behavior of the drug, which in turn affects the efficacy and therapeutic effect of the drug.

Due to affecting the release and absorption of drugs, products such as swallowing aid gels or inhalable jellies in the prior art are basically not suitable for assisting swallowing of oral drugs

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