Esters for treatment of ocular inflammatory conditions
An eye disease, ophthalmology technology, applied in the field of eye products, can solve problems such as disorders, bleeding time effects, increased cholesterol levels, etc.
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[0015] Methods of making and using ophthalmic products comprising esterified anti-inflammatory lipid mediators, wherein the majority of the anti-inflammatory lipid mediators are present in the ester form are provided. It has been found that the use of esterified anti-inflammatory lipid mediators (when the majority of the anti-inflammatory lipid mediator is present in the ester form) results in ophthalmic products with greatly improved initial comfort upon contact with or application to ocular surfaces . Ophthalmic products include, but are not limited to, any formulation, solution, gel, ointment, lotion, strip, ophthalmic device, etc. that can be applied to ocular surfaces, including the eye.
[0016] With respect to terms used in this disclosure, the following definitions are provided.
[0017] References to "anti-inflammatory lipid mediators" include those molecules that inhibit (directly or indirectly) the production of cytokines by epithelial or immune cells, inhibit the ...
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