A traditional Chinese medicine composition for treating hyperthyroidism and its preparation method and application

Abstract

The invention belongs to the field of medicine, and relates to a traditional Chinese medicine composition for treating hyperthyroidism, a preparation method and application thereof. The traditional Chinese medicine composition is prepared from the following Chinese medicinal materials in parts by weight: 10-20 parts of Morinda officinalis, 12-18 parts of Scutellaria barbata, 6-10 parts of Semen Cassiae, 10-15 parts of Xu Changqing, 10-20 parts of Rhizoma Chuanxiong, 12-16 parts of wild chrysanthemum, 6-9 parts of Salvia miltiorrhiza, 20-30 parts of Luo Han Guo, 20-30 parts of Astragalus, 10-16 parts of Bupleurum, 12-18 parts of Poria cocos, 15-25 parts of Scutellaria baicalensis, 10-20 parts of Tribulus terrestris , 6-12 parts of white peony, 15-20 parts of Atractylodes macrocephala, 10-15 parts of licorice. The traditional Chinese medicine composition has the advantages of definite curative effect and low side effects in treating hyperthyroidism.

Description

technical field

[0001] The invention belongs to the field of medicine, and in particular relates to a traditional Chinese medicine composition, a preparation method thereof and an application as a drug for treating hyperthyroidism. Background technique

[0002] Hyperthyroidism, referred to as "hyperthyroidism", is a disease in which the thyroid gland synthesizes and releases excessive thyroid hormones, causing hypermetabolism and sympathetic nerve excitement, causing palpitations, sweating, increased eating and stool frequency, and weight loss. Most patients also often have exophthalmos, eyelid edema, vision loss and other symptoms at the same time. Thyroid hormones promote metabolism and promote redox reactions in the body. Hypermetabolism requires the body to eat more food; gastrointestinal activity increases, and the number of stools increases; although food intake increases, oxidation reactions increase, body energy consumption increases, and patients show weight loss; h...

Examples

Embodiment 1

[0019] The preparation of embodiment 1 Chinese medicine mixture

[0020] Prescription: Morinda officinalis 10g, Scutellaria barbata 12g Cassia 6g, Xu Changqing 10g, Rhizoma Chuanxiong 10g, Wild chrysanthemum 12g, Salvia miltiorrhiza 6g, Luo Han Guo 20g, Astragalus 20g, Bupleurum 10g, Poria cocos 12g, Scutellaria baicalensis 15g, Tribulus terrestris 10g, Paeoniae Alba 6g , Atractylodes macrocephala 15g, licorice 10g.

[0021] Preparation method: Take the medicinal materials of the above weight components, add water 5 times the total weight of the medicinal materials, soak for 30 minutes, decoct twice for 2 hours each time, filter, combine the filtrates, and concentrate the filtrates under reduced pressure to a relative density of 1.1 The extract, the relative density is the test result at 60 degrees Celsius, add ethanol until the alcohol content is 75% (v / v), let it stand for 24 hours, take the supernatant, recover the ethanol to concentrate, add water to 600ml, stir Evenly, ...

Embodiment 2

[0022] The preparation of embodiment 2 Chinese medicine tablet

[0023] Prescription: 20 parts of Morinda officinalis, 18 parts of Banzhilian, 10 parts of Cassia, 15 parts of Xu Changqing, 20 parts of Chuanxiong, 16 parts of wild chrysanthemum, 9 parts of Salvia, 30 parts of Luo Han Guo, 30 parts of Astragalus, 16 parts of Bupleurum, and 18 parts of Poria 25 parts of Scutellaria baicalensis, 20 parts of Tribulus terrestris, 12 parts of white peony, 20 parts of Atractylodes macrocephala, 15 parts of licorice.

[0024] Preparation method: Take each medicinal material of the above weight components, add water 10 times the total weight of the medicinal materials, soak for 60 minutes, decoct once, 1 hour each time, filter, combine the filtrate, and concentrate the filtrate under reduced pressure to a relative density of 1.25 The extract, the relative density is the test result at 60 degrees Celsius, add ethanol until the alcohol content is 80% (v / v), let it stand for 24 hours, ta...

Embodiment 3

[0025] The preparation of embodiment 3 Chinese medicine capsules

[0026] Prescription: 15 parts of Morinda officinalis, 15 parts of Banzhilian, 8 parts of Cassia, 12 parts of Xu Changqing, 15 parts of Chuanxiong, 14 parts of wild chrysanthemum, 8 parts of Salvia, 25 parts of Luo Han Guo, 25 parts of Astragalus, 12 parts of Bupleurum, and 14 parts of Poria , 20 parts of Scutellaria baicalensis, 15 parts of Tribulus terrestris, 9 parts of white peony, 18 parts of Atractylodes macrocephala, and 12 parts of licorice.

[0027] Preparation method: Take the medicinal materials of the above weight components, add water 8 times the total weight of the medicinal materials, soak for 45 minutes, decoct 4 times for 1.5 hours each time, filter, combine the filtrate, and concentrate the filtrate under reduced pressure to a relative density of 1.2 The extract, the relative density is the test result at 60 degrees Celsius, add ethanol until the alcohol content is 90% (v / v), let it stand for...

technical field

[0001] The invention belongs to the field of medicine, and in particular relates to a traditional Chinese medicine composition, a preparation method thereof and an application as a drug for treating hyperthyroidism. Background technique

[0002] Hyperthyroidism, referred to as "hyperthyroidism", is a disease in which the thyroid gland synthesizes and releases excessive thyroid hormones, causing hypermetabolism and sympathetic nerve excitement, causing palpitations, sweating, increased eating and stool frequency, and weight loss. Most patients also often have exophthalmos, eyelid edema, vision loss and other symptoms at the same time. Thyroid hormones promote metabolism and promote redox reactions in the body. Hypermetabolism requires the body to eat more food; gastrointestinal activity increases, and the number of stools increases; although food intake increases, oxidation reactions increase, body energy consumption increases, and patients show weight loss; h...

Examples

Embodiment 1

[0019] The preparation of embodiment 1 Chinese medicine mixture

[0020] Prescription: Morinda officinalis 10g, Scutellaria barbata 12g Cassia 6g, Xu Changqing 10g, Rhizoma Chuanxiong 10g, Wild chrysanthemum 12g, Salvia miltiorrhiza 6g, Luo Han Guo 20g, Astragalus 20g, Bupleurum 10g, Poria cocos 12g, Scutellaria baicalensis 15g, Tribulus terrestris 10g, Paeoniae Alba 6g , Atractylodes macrocephala 15g, licorice 10g.

[0021] Preparation method: Take the medicinal materials of the above weight components, add water 5 times the total weight of the medicinal materials, soak for 30 minutes, decoct twice for 2 hours each time, filter, combine the filtrates, and concentrate the filtrates under reduced pressure to a relative density of 1.1 The extract, the relative density is the test result at 60 degrees Celsius, add ethanol until the alcohol content is 75% (v / v), let it stand for 24 hours, take the supernatant, recover the ethanol to concentrate, add water to 600ml, stir Evenly, ...

Embodiment 2

[0022] The preparation of embodiment 2 Chinese medicine tablet

[0023] Prescription: 20 parts of Morinda officinalis, 18 parts of Banzhilian, 10 parts of Cassia, 15 parts of Xu Changqing, 20 parts of Chuanxiong, 16 parts of wild chrysanthemum, 9 parts of Salvia, 30 parts of Luo Han Guo, 30 parts of Astragalus, 16 parts of Bupleurum, and 18 parts of Poria 25 parts of Scutellaria baicalensis, 20 parts of Tribulus terrestris, 12 parts of white peony, 20 parts of Atractylodes macrocephala, 15 parts of licorice.

[0024] Preparation method: Take each medicinal material of the above weight components, add water 10 times the total weight of the medicinal materials, soak for 60 minutes, decoct once, 1 hour each time, filter, combine the filtrate, and concentrate the filtrate under reduced pressure to a relative density of 1.25 The extract, the relative density is the test result at 60 degrees Celsius, add ethanol until the alcohol content is 80% (v / v), let it stand for 24 hours, ta...

Embodiment 3

[0025] The preparation of embodiment 3 Chinese medicine capsules

[0026] Prescription: 15 parts of Morinda officinalis, 15 parts of Banzhilian, 8 parts of Cassia, 12 parts of Xu Changqing, 15 parts of Chuanxiong, 14 parts of wild chrysanthemum, 8 parts of Salvia, 25 parts of Luo Han Guo, 25 parts of Astragalus, 12 parts of Bupleurum, and 14 parts of Poria , 20 parts of Scutellaria baicalensis, 15 parts of Tribulus terrestris, 9 parts of white peony, 18 parts of Atractylodes macrocephala, and 12 parts of licorice.

[0027] Preparation method: Take the medicinal materials of the above weight components, add water 8 times the total weight of the medicinal materials, soak for 45 minutes, decoct 4 times for 1.5 hours each time, filter, combine the filtrate, and concentrate the filtrate under reduced pressure to a relative density of 1.2 The extract, the relative density is the test result at 60 degrees Celsius, add ethanol until the alcohol content is 90% (v / v), let it stand for...