The invention relates to the technical field of traditional Chinese medicine, and particularly relates to a cream for treating eczema and a preparation method of the cream. The cream is composed of atraditional Chinese medicinal compound extract and auxiliary materials, wherein the traditional Chinese medicinal compound extract is prepared from the following raw materials in parts by weight: 25-30 parts of herba selaginellae, 50-65 parts of zaocys, 25-30 parts of herba ephedrae, 25-35 parts of herba lobeliae chinensis, 25-35 parts of rhizoma notopterygii, 10-20 parts of herba schizonepetae, 30-40 parts of rhizoma zingiberis, 25-35 parts of flos lonicerae, 10-15 parts of radix glycyrrhizae, 10-15 parts of herba menthae and 15-20 parts of radix salviae miltiorrhizae. The cream provided by the invention is mainly used for clearing away heat and dampness, expelling wind and itching, has good treatment effect on eliminating various symptoms caused by eczema, enables a recurrence rate to bereduced, and is convenient to use, free of toxic and side effects, convenient to promote and apply, simple in preparation process, and industrialized large-scale production can be realized.