Traditional Chinese medicine composition for treating glioma and preparation method of traditional Chinese medicine composition

A technology of glioma and composition, which is applied in the field of medicine and can solve the problems of high toxicity and side effects of chemotherapy drugs

Inactive Publication Date: 2015-04-29
潘焱
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Aiming at the lack of effective chemotherapeutic drugs in the existing glioma treatment and the defects of large toxic and side effects of chemotherapeutic drugs, in order to provide a safe and effective anti-glioma drug and increa...

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0011] Example 1 The traditional Chinese medicine composition mixture of the present invention

[0012] Prescription: Dodder seed 20g, Xu Changqing 6g, Acanthopanax 10g, Plantain 10g, Evodia 10g, Won Scutellariae 20g, Rehmannia glutinosa 15g, Araceae 13g, Wormwood 5g, Jujube seed 5g, Honeysuckle 10g, Jiaoshan Zhi 12g, Diyu 8g, Oldenlandia diffusa 9g, Pueraria lobata 11g, Tripterygium wilfordii 4g, Licorice 10g.

[0013] Preparation method: Take each medicinal material of the above weight components, add 5 times the total weight of the medicinal material in water, soak for 30 minutes, decoct 2 times, 2 hours each time, filter, combine the filtrate, and concentrate the filtrate under reduced pressure to a relative density of 1.1 The relative density is the test result at 60 degrees Celsius, add ethanol to 75% (v / v) of alcohol content, let stand for 24 hours, take the supernatant, recover the ethanol and concentrate, add water to 1000ml, stir Homogenize, pack, and sterilize with circ...

Embodiment 2

[0014] Example 2 Chinese medicine composition tablet of the present invention

[0015] Prescription: Cuscuta seed 200g, Xu Changqing 60g, Acanthopanax senticosus 100g, Plantain 100g, Evodia 100g, Won Scutellariae 200g, Rehmannia glutinosa 150g, Araceae 130g, Wormwood 50g, Jujube seed 50g, Honeysuckle 100g, Jiaoshan Zhi 120g, Diyu 80g, Oldenlandia diffusa 90g, Pueraria lobata 110g, Tripterygium wilfordii 40g, Licorice 100g.

[0016] Preparation method: Take each medicinal material of the above weight components, add 10 times the total weight of the medicinal material in water, soak for 60 minutes, decoct once for 1 hour, filter, combine the filtrate, and concentrate the filtrate under reduced pressure to a relative density of 1.25 The relative density is the test result at 60 degrees Celsius. Add ethanol to 80% alcohol content (v / v), let it stand for 24 hours, take the supernatant, recover the ethanol to concentrate, vacuum dry and prepare Granules, compressed into tablets.

Embodiment 3

[0017] Example 3 Chinese medicine composition capsules of the present invention

[0018] Prescription: Dodder seed 2000g, Xu Changqing 600g, Acanthopanax 1000g, Plantain 1000g, Evodia 1000g, Won Scutellariae 2000g, Rehmannia glutinosa 1500g, Araceae 1300g, Wormwood 500g, Jujube seed 500g, Honeysuckle 1000g, Jiaoshan Zhi 1200g, Diyu 800g, Oldenlandia diffusa 900g, Pueraria lobata 1100g, Tripterygium wilfordii 400g, Licorice 1000g.

[0019] Preparation method: Take each medicinal material of the above weight components, add 8 times the total weight of the medicinal material in water, soak for 45 minutes, decoct 4 times, 1.5 hours each time, filter, combine the filtrate, and concentrate the filtrate under reduced pressure to a relative density of 1.2 The relative density is the test result at 60 degrees Celsius. Add ethanol to 90% alcohol content (v / v), let it stand for 24 hours, take the supernatant, recover the ethanol to concentrate, vacuum dry, and prepare Get it in capsules.

[0...

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Abstract

The invention relates to a traditional Chinese medicine composition for treating glioma and a preparation method and application of the traditional Chinese medicine composition. The traditional Chinese medicine composition for treating glioma comprises the following components in parts by weight: 20 parts of semen cuscutae, 6 parts of radix cynanchi paniculati, 10 parts of radix et caulis acanthopanacis senticosi, 10 parts of herba plantaginis, 10 parts of fructus evodiae, 20 parts of wogonin, 15 parts of rehmannia dride rhizome, 13 parts of rhizoma arisaematis, 5 parts of wormwood, 5 parts of semen ziziphi spinosae, 10 parts of flos lonicerae, 12 parts of fructus gardeniae preparatus, 8 parts of radix sanguisorbae, 9 parts of herba hedyotis, 11 parts of radix puerariae, 4 parts of tripterygium wilfordii hook. f and 10 parts of radix glycyrrhizae. The traditional Chinese medicine composition achieves a good treatment effect on the aspect of treating glioma, and has significant clinical popularization values.

Description

Technical field [0001] The invention belongs to the field of medicine, and relates to a traditional Chinese medicine composition and a preparation method thereof, in particular to a traditional Chinese medicine composition for treating glioma, and a preparation method and application thereof. Background technique [0002] Glioma is a tumor that occurs in the neuroectoderm, so it is also called neuroectodermal tumor or neuroepithelial tumor. Glioma is a high-recurrence brain tumor disease with the characteristics of "three highs and one low" such as morbidity, recurrence, high mortality and low cure rate. The etiology of its incidence is still unclear. Glioma (glioma) accounts for about 46% of intracranial tumors, with an incidence of 3-10 people per 100,000 people, and the peak age of onset is 30-40 years old, or 10-20 years old. Glioma accounts for 1% to 3% of systemic malignant tumors, and the average survival period of surgery plus radiotherapy and chemotherapy is only 8 to 1...

Claims

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Application Information

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IPC IPC(8): A61K36/8884A61P35/00A61P29/00A61P11/10A61P1/16A61P1/14
CPCA61K36/254A61K36/27A61K36/282A61K36/355A61K36/37A61K36/39A61K36/484A61K36/488A61K36/539A61K36/68A61K36/725A61K36/739A61K36/744A61K36/748A61K36/754A61K36/804A61K36/8884A61K2236/331A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 胡学荣
Owner 潘焱
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