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43results about How to "Reduce tumor weight" patented technology
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Compounds and methods for treatment of cancer
ActiveUS8530404B2Altering activity of tumorReduce tumor volumeBiocidePeptide/protein ingredientsCancer preventionLymphatic Spread
Owner:FIBROGEN INC
Application of protosappanin B in preparation of bladder cancer resistant perfusion fluid
InactiveCN102670578AGood killing effectProlong lifeOrganic active ingredientsUrinary disorderHuman bladderCancer cell
The invention relates to application of protosappanin B, in particular to application of a 0.2 to 2.4 percent protosappanin B solution in preparation of bladder cancer resistant perfusion fluid. For filling up the research blank of the protosappanin B at home and abroad, the invention provides new application of the protosappanin B. Human bladder cancer cell strains T24 or mouse bladder cancer cell strains BTT are inoculated to mouse bodies to form bladder cancer, and the mice are grouped and respectively subjected to experiments with injection water, mitomycin and the protosappanin B; experiment results show that the lives of the mice injected with the mitomycin and the protosappanin B are prolonged, the tumor weight is reduced, and a tumor inhibiting effect is achieved; and the protosappanin B has a remarkable bladder cancer inhibiting effect, and can be widely applied to preparation of the bladder cancer resistant perfusion fluid.
Owner:山西华尚汇商贸有限公司
Diazeniumdiolated compounds, pharmaceutical compositions, and method of treating cancer
ActiveUS20120238518A1Reduce the overall heightReduce tumor weightBiocideOrganic chemistryCancer cellMedicine
Disclosed is a method of treating cancer in a patient comprising administering to the patient an effective amount of a diazeniumdiolated (N2O2-containing) compound or a pharmaceutically acceptable salt thereof, wherein the cancer cell has an elevated level of reactive oxygen species (ROS) and / or a decreased level of one or more of PRX1, PRX6, and OGG1, compared to a normal cell of the same tissue or tissue type. An example of a diazeniumdiolated compound is Formula (I), wherein X and Q are defined herein. Also disclosed are diazeniumdiolated compounds, pharmaceutical compositions, and methods of use including enhancing the chemotherapeutic treatment of chemotherapeutic agents and high energy radiation.
Owner:UNITED STATES OF AMERICA
Fusion protein of human interferon and targeting peptide, and preparation thereof
The present invention provides a fusion protein of human interferon and a targeting peptide, and preparation thereof. The fusion protein has a structure of IFN-M-S, wherein S represents a targeting peptide, M represents a linkage peptide, IFN represents interferon, an amino acid sequence of S can be any one selected from S1, S2, S3 and S4, an amino acid sequence of M contains 0-10 amino acid residues, preferably 4-6 amino acid residues, and IFN can be any one of I type interferon and II type interferon.
Owner:哈药集团股份有限公司 +1
Antineoplastic Chinese traditional compound and the preparation and the method for producing the same
ActiveCN101040899ASimple preparation processIncrease contentPill deliveryCapsule deliverySophora RootChinese traditional
The invention relates to an antineoplastic Chinese medicinal composition and preparing process thereof, wherein the composition has appreciable effect in treating malignant tumor such as digestive tract tumor. The invention provides the significant part of subprostrate sophora root alkaloids extracted from subprostrate sophora root and the related preparing process. The alkaloids content in the subprostrate sophora root alkaloid significant part is higher than 50%. The invention further provides a Chinese medicinal preparation using subprostrate sophora root alkaloids as the medicinal effective composition.
Owner:北大世佳科技开发有限公司
Medicament for treating tumors and preparation method thereof
InactiveCN101590209AHeavy growth rate increaseSignificant exorcising effectAnthropod material medical ingredientsAntineoplastic agentsHerba Scutellariae BarbataeSolvent
The invention discloses a medicament composition for treating tumors, which is a Chinese medicinal preparation mainly prepared from the raw materials such as rabdosia rubescens, salvia chinensis, seaweed, zedoary, ground beetles, herba scutellariae barbatae, Indian mockstrawberry herb, bistort rhizome, astragalus roots, liquorice and coix seeds. The medicament has the advantages of simple unique prescription, low price, remarkable efficacy, effects of strengthening healthy energy and eliminating pathogens, as well as synergism. The invention also discloses a method for preparing the medicament. The medicament is prepared by extracting Chinese medicaments with different solvents respectively, performing other pretreatment and then compounding the obtained products pro rata according to the different characteristics of each Chinese medicament.
Owner:郭凯
Isoflavones composition and medicine made of same
InactiveCN102949388AGood treatment effectProlong survival timeUrinary disorderRespiratory disorderIsoflavonesVeterinary medicine
The invention discloses an isoflavones composition and medicine made of the same. The isoflavones composition comprises methylophiopogonanone B, methylophiopogonanone A, 6-formylisoophiopogonone A, 5,7,2',6'-tetrahydroxy-4'-methoxyl-6,8-dimethylophiopogonanone, ophiopogonanone E, 5,7,4'-trihydroxy-3'-methoxyl-6,8-dimethylophiopogonanone, 2,5,7- trihydroxy-4'-methoxyl-6,8-dimethylophiopogonanone, 6-formylisoophiopogonone B, 5,7,4'-trihydroxy-6-dimethylophiopogonanone and 5,7,4'-trihydroxy-6-methylophiopogonanone. The medicine can be used for treatment and prevention of cancers.
Owner:苏州同立医药技术有限公司
Uses of calenduloside E in preparation of anti-tumor medicines
InactiveCN105535003AAntitumor effect hasAnti-tumorOrganic active ingredientsPill deliveryCell activityIn vivo
The invention provides uses of calenduloside E in preparation of anti-tumor medicines. Experiments about influences of the calenduloside E on activity of B16F10 melanoma cells prove that the calenduloside E can inhibit activity of tumor cells. Experiments about influences of the calenduloside E on activity of human umbilical vein endothelial cells (HUVECs) and lumen formation experiments prove that the calenduloside E can inhibit activity of vascular endothelial cells and inhibit lumen formation capability of the vascular endothelial cells. Experiments about influences of calenduloside E administration on growth of B16F10 melanoma cells in mice prove that the calenduloside E can inhibit in-vivo tumor cell growth and has anti-tumor activity.
Owner:INST OF SPECIAL ANIMAL & PLANT SCI OF CAAS
Medicament for treating tumors and preparation method thereof
InactiveCN101745052AHeavy growth rate increaseSignificant exorcising effectAnthropod material medical ingredientsAntineoplastic agentsBarbed Skullcap HerbCurative effect
The invention discloses a medicinal composition for treating tumors, which is a Chinese medicinal preparation prepared by using Chinese sage herb, seaweed, common burreed rhizome, barbed skullcap herb, Indian mockstrawberry herb and bistort rhizome as the main raw materials. The invention has simple and unique formula, low price and obvious curative effect, and has effects of strengthening the body resistance, eliminating the pathogenic factor and enhancing effectiveness. The invention also discloses a preparation method for the medicament. The medicament is prepared according to different characteristics of each Chinese medicament in proportion after pretreatments of extracting respectively by different solvents and the like.
Owner:郭凯
Application of compound in preparation of drugs for treatment of renal cell carcinoma
ActiveCN110638820AReduce cell viabilityReduce tumor weightOrganic active ingredientsAntineoplastic agentsTumor WeightOncology
The invention discloses application of 1,2,3,4,6-pentagalloylglucose, or an optical isomer, or a racemate, or a solvate, or a pharmaceutically acceptable salt in the preparation of drugs for the treatment or prevention of renal cancer or prostate cancer. According to the application, an experiment shows that the 1,2,3,4,6-pentagalloylglucose can significantly reduce the cell activity of Renca renal cancer and RM-1 prostate cancer in vitro, can reduce the tumor weight of tumor bearing mice in vivo, and it is proved that the 1,2,3,4,6-pentagalloylglucose has an inhibitory effect on two kinds oftumors, and PD-L1 gene expression is detected in two kinds of tumor bearing mice, so that it can be preliminarily inferred that the 1,2,3,4,6-pentagalloylglucose may play an anti-tumor role mainly byblocking PD1 / PD-L1.
Owner:JIANGSU KANION PHARMA CO LTD
Total alkaloids of subprostrate sophora root soft capsules and preparation method and application thereof
ActiveCN101077349AIncrease alkaloid contentClear ingredientsOrganic active ingredientsPharmaceutical non-active ingredientsSophora RootSoftgel
The present invention discloses one kind of soft capsule of tonkin sophora root total alkaloid. The soft capsule consists of two parts, inclusion and covering. The inclusion includes Tonkin sophora root total alkaloid, dispersing medium and stabilizer; and the covering includes gelatin, glycerin, water and preservative. The present invention also discloses the preparation process. The preparation process is simple, and the soft capsule of tonkin sophora root total alkaloid has high stability, controllable quality, easy taking and high antitumor effect.
Owner:北大世佳科技开发有限公司
1,2-dicarboxylic acid mono-amide taken as chemotherapy synergist
InactiveCN108938663AImprove permeabilityImprove anti-cancer effectOrganic active ingredientsPharmaceutical delivery mechanismCancer cellCarboxylic acid
The invention discloses an application of a polymer as a synergist of a chemotherapy drug. The polymer contains a 1,2-dicarboxylic acid mono-amide structure. After the polymer, a chemotherapy drug, and cancer cells are co-cultured in a slightly acidic environment of simulated tumor tissues, the survival rate of cancer cells is lower than the survival rate of cancer cells that are not subjected toco-culture under same conditions; and after the polymer and the chemotherapy drug are injected into cancer bearing animals, the effect on inhibiting tumor growth is better, compared with the situationthat only the chemotherapy drug with a same dose is injected.
Owner:NANKAI UNIV
Antitumor traditional Chinese medicinal composition and antitumor active component composition, and use and preparation thereof
InactiveCN108553495AReduce tumor weightImprove the quality of lifeOrganic active ingredientsMammal material medical ingredientsCholic acidPANAX NOTOGINSENG ROOT
The invention relates to a traditional Chinese medicinal composition, and concretely relates to an antitumor traditional Chinese medicinal composition and an antitumor active component composition, and a use and a preparation thereof. The antitumor traditional Chinese medicinal composition comprises, by weight, 30-60 parts of Panax Notoginseng, 5-15 parts of artificial bezoar, 1-8 parts of artificial musk and 1-10 parts of snake galls. The antitumor active component composition comprises, by weight, 10-30 parts of Panax notoginseng saponins, 1-8 parts of cholic acid, 0.1-1 part of musk ketoneand 0.1-1 part of taurocholic acid. The traditional Chinese medicinal composition or the active component composition has the advantages of low price, clear components, clear mechanism, accurate dosage, safety and effectiveness, and is used for preventing or treating various malignant tumors.
Owner:FUJIAN UNIV OF TRADITIONAL CHINESE MEDICINE
Anti-tumor traditional Chinese medicinal composition and preparation method and medicinal preparation thereof
ActiveCN101099756AIncrease contentSmall side effectsOrganic active ingredientsOrganic chemistryDrugs preparationsSolvent
The present invention relates to a picrasma quassioides extract obtained by using Chinese medicinal material picrasma quassioides as raw material and adopting solvent extraction and resin separation and purification processes. The total alkaloid content in said extract is above 50%. Said invention also provides a pure Chinese medicine preparation containing said picrasma quassioides extract for resisting tumor and its concrete preparation method.
Owner:北大世佳科技开发有限公司
Nanoliposomal c-MYC-siRNA Inhibits In Vivo Tumor Growth of Cisplatin-Resistant Ovarian Cancer
ActiveUS20150306036A1Significant cell growth arrestDecreased tumor number of tumorHeavy metal active ingredientsOrganic active ingredientsOvarian cancer cell lineTumor Weight
The present invention discloses c-MYC-siRNA formulation as a potential therapeutic target for cisplatin-resistant ovarian cancer. It is disclosed targeting c-MYC with small interfering RNA (siRNA) in the cisplatin-resistant ovarian cancer cell line inducing a significant cell growth arrest and inhibition of cell proliferation. Apoptosis and arrest of cell cycle progression were also observed after c-MYC-siRNA-based silencing of c-MYC. Furthermore, delivering nanoliposomal c-MYC-siRNA, decreased tumor weight and number of tumor nodules compared with a liposomal-negative control siRNA.
Owner:VIVAS MEJIA PABLO E +2
KD (ketogenic-diet) composition eaten by tumor patients and preparation method of KD composition
InactiveCN108936626AImprove anti-tumor effectGood treatment effectLipidic food ingredientsNatural extract food ingredientsWilms' tumorDietary fiber
The invention relates to a KD (ketogenic-diet) composition eaten by tumor patients and a preparation method of the KD composition. The composition comprises raw materials in parts by mass as follows:1 part of fats, 0.1-0.8 part of protein, 0.2-0.4 part of dietary fiber and 0.05-0.2 part of whole silkworm freeze-dried powder. The whole silkworm freeze-dried powder is freeze-dried powder obtained after ultralow-temperature freezing and crushing of adult silkworms. The preparation method of the KD composition comprises the 5 steps as follows: raw material cleaning, ultralow-temperature freezing,spray drying, powdering and mixing, disinfection and packaging. In the KD composition, the dietary fiber and the whole silkworm freeze-dried powder are added clearly, and the proportions of the dietary fiber and the whole silkworm freeze-dried powder are clear; and the KD composition can supplement high-quality protein through the whole silkworm freeze-dried powder and enhance immunity, KD can selectively make tumor cells hungry, physiological ketonemia can regulate key accesses in production and development of tumor, anti-tumor acting bodies can be produced, and the KD composition can be directly eaten by various cancer patients as a food therapy substance.
Owner:唐山英盛生物科技有限公司
Traditional Chinese medicine composition for treating brain glioma and preparation method of traditional Chinese medicine composition
InactiveCN105079704AEnhance anti-inflammatoryGood anti-inflammatory effectAntineoplastic agentsPlant ingredientsTreatment effectAdditive ingredient
The invention belongs to the field of traditional Chinese medicine, and particularly relates to a traditional Chinese medicine composition for treating brain glioma as well as a preparation method and application of the traditional Chinese medicine composition. The traditional Chinese medicine composition comprises the following ingredients by weight: 20 parts of ganoderma, 6 parts of mint, 10 parts of cenchrus echinatus, 10 parts of purslane, 10 parts of malus hupehensis leaf, 20 parts of astragalus membranaceus, 15 parts of ligusticum wallichii, 13 parts of hairyvein agrimonia herb and bud, 5 parts of turmeric, 5 parts of lily, 10 parts of radix paeoniae rubra, 12 parts of radix codonopsitis, 8 parts of panax notoginseng, 9 parts of coptis chinensis, 11 parts of centella, 4 parts of lucid asparagus, and 10 parts of poria cocos. The traditional Chinese medicine composition has an excellent curative effect on treating brain glioma, and has a remarkable clinical popularization value.
Owner:邹士东
Traditional Chinese medicine composition for treating glioma and preparation method of traditional Chinese medicine composition
InactiveCN104547362AEnhance anti-inflammatoryGood anti-inflammatory effectAntipyreticDigestive systemTherapeutic effectRehmannia glutinosa
The invention relates to a traditional Chinese medicine composition for treating glioma and a preparation method and application of the traditional Chinese medicine composition. The traditional Chinese medicine composition for treating glioma comprises the following components in parts by weight: 20 parts of semen cuscutae, 6 parts of radix cynanchi paniculati, 10 parts of radix et caulis acanthopanacis senticosi, 10 parts of herba plantaginis, 10 parts of fructus evodiae, 20 parts of wogonin, 15 parts of rehmannia dride rhizome, 13 parts of rhizoma arisaematis, 5 parts of wormwood, 5 parts of semen ziziphi spinosae, 10 parts of flos lonicerae, 12 parts of fructus gardeniae preparatus, 8 parts of radix sanguisorbae, 9 parts of herba hedyotis, 11 parts of radix puerariae, 4 parts of tripterygium wilfordii hook. f and 10 parts of radix glycyrrhizae. The traditional Chinese medicine composition achieves a good treatment effect on the aspect of treating glioma, and has significant clinical popularization values.
Owner:潘焱
Preparation of dendrobium officinale polysaccharide lozenge and application of dendrobium officinale polysaccharide lozenge in immunopotentiation
PendingCN111557447ASignificant immune enhancement effectReasonable process designOrganic active ingredientsPharmaceutical non-active ingredientsWhite blood cellMagnesium stearate
The invention discloses preparation of a dendrobium officinale polysaccharide lozenge and an application of the dendrobium officinale polysaccharide lozenge in immunopotentiation. The total extractionprocess of the polysaccharide comprises the following steps: decocting and extracting dendrobium officinale coarse powder with 40 times of water for 2 hours, filtering, concentrating the filtrate to0.2 g of crude drug / ml, and precipitating with 5 times of ethanol by a water extraction and alcohol precipitation method to obtain the dendrobium officinale polysaccharide powder. The mannitol, aspartame, magnesium stearate, microcrystalline cellulose, menthol and povidone are added into the dendrobium polysaccharide powder to prepare lozenge. The lozenge can improve yin deficiency symptoms of yindeficiency model mice caused by thyroid hormone. Peripheral blood leukocyte WBC reduction of S180 tumor-bearing mice caused by 60Co radiotherapy is improved, and the number of bone marrow nucleated cells is increased. The effects of improving the activity of the body, resisting oxidative damage and enhancing immunity are shown. The dendrobium officinale polysaccharide lozenge prepared by the optimal dendrobium officinale polysaccharide extraction process screened by the invention has an obvious immunopotentiation effect, and can be used in the fields of immunopotentiation medicines, health-care products and foods.
Owner:上海市浦东新区浦南医院
Combination therapy using C-C chemokine receptor 4 (CCR4) antagonists and one or more immune checkpoint inhibitors
ActiveUS11446289B2Reduce tumor weightOrganic active ingredientsColon cancer vaccineChemokine Receptor AntagonistCancer therapy
The present disclosure is drawn to the combination therapy of a C—C Chemokine Receptor 4 (CCR4) antagonist and one or more immune checkpoint inhibitors in the treatment of cancer.
Owner:CHEMOCENTRYX INC
Camptothecin-based dimer compound as well as preparation and application thereof
ActiveCN112321615AImprove anti-tumor effectReduce tumor volumeOrganic active ingredientsOrganic chemistryDimerTumor chemotherapy
The invention belongs to the technical field of medicines, and particularly relates to a camptothecin-based dimer compound as well as preparation and application thereof. The dimer compound has a structure represented by a formula (I), wherein in the formula (I), m is an integer of 1-4, and n is an integer of 1-4. The dimer compound is connected with camptothecin and immunomodulatory small molecules NLG919 through reductive disulfide bonds, so that combination of tumor chemotherapy and immunotherapy is realized, and the anti-tumor curative effect is enhanced. The compound prepared by the invention can be reduced into original camptothecin and NLG919 under a reducing condition, has good anti-tumor activity in tumors such as liver cancer, breast cancer, colon cancer, melanoma, ovarian cancerand the like, and can be used for inhibiting the activity of indoleamine 2,3-oxygenase, increasing DC cell maturation and reducing the number of immunosuppressive Treg cells; the drug resistance of tumor stem cells to camptothecin is reduced, and the tumor immune response is enhanced.
Owner:HUAZHONG UNIV OF SCI & TECH
Combination therapy using c-c chemokine receptor 4 (CCR4) antagonists and one or more immune checkpoint inhibitors
ActiveUS20200069673A1Reduce tumor weightOrganic active ingredientsColon cancer vaccineChemokine Receptor AntagonistCancer therapy
The present disclosure is drawn to the combination therapy of a C—C Chemokine Receptor 4 (CCR4) antagonist and one or more immune checkpoint inhibitors in the treatment of cancer.
Owner:CHEMOCENTRYX INC
Synergetic medicinal composition for nasopharynx cancer chemoradiotherapy
InactiveCN104288406AReduce tumor weightImprove tumor inhibition rateAntineoplastic agentsConiferophyta medical ingredientsRed CloverGleditsia triacanthos
The invention discloses a synergetic medicinal composition for nasopharynx cancer chemoradiotherapy, and aims to solve the treatment problem of nasopharynx cancer. The synergetic medicinal composition is characterized by comprising the following raw medicinal materials in percentage by weight: elsholtzia rugulosa, pungent litse flower, leycesteria formosa, rhizoma pinelliae, polygonum multiflorum, trifolium pratense, groundsel, Chinese honey locust, acorus gramineus, cassia twig and peach gum. The clinical experiments show that the synergetic medicinal composition is synergetic with the chemotherapy, good in in curative effect, high in safety, and worthy of clinical application and popularization.
Owner:所俊强
Total alkaloids of subprostrate sophora root soft capsules and preparation method and application thereof
ActiveCN101077349BGood treatment effectReduce tumor weightOrganic active ingredientsPharmaceutical non-active ingredientsSophora RootDispersed media
The present invention discloses one kind of soft capsule of tonkin sophora root total alkaloid. The soft capsule consists of two parts, inclusion and covering. The inclusion includes Tonkin sophora root total alkaloid, dispersing medium and stabilizer; and the covering includes gelatin, glycerin, water and preservative. The present invention also discloses the preparation process. The preparationprocess is simple, and the soft capsule of tonkin sophora root total alkaloid has high stability, controllable quality, easy taking and high antitumor effect.
Owner:北大世佳科技开发有限公司
Method of treating leukemia using rice prolamin
ActiveUS9333236B2Growth inhibitionReduce tumor weightPeptide/protein ingredientsHuman leukemiaPeripheral blood mononuclear cell
The present invention relates to a method of treating leukemia using rice prolamin, comprising administering a daily dose of isolated prolamin to a patient suffering from leukemia for a period of time from 5 days to 10 days. For the treatment application, the rice prolamin can stimulate human peripheral blood mononuclear cell (PBMC) to produce cytokines, such as tumor necrosis factor-alpha, to inhibit growth of and induce differentiation of human leukemia cells. The rice prolamin is gluten-free, thus will not trigger gastrointestinal allergic reaction, it also can decrease the tumor weight without changes in body weight and can inhibit the growth of peripheral blood leukocyte in leukemia mouse model.
Owner:MACKAY MEMORIAL HOSPITAL
Medicament for treating tumors and preparation method thereof
InactiveCN101745052BHeavy growth rate increaseSignificant exorcising effectAnthropod material medical ingredientsAntineoplastic agentsBarbed Skullcap HerbCurative effect
Owner:郭凯
Method of treating leukemia using rice prolamin
ActiveUS20150051156A1Growth inhibitionReduce tumor weightPeptide/protein ingredientsAntineoplastic agentsHuman leukemiaWhite blood cell
The present invention relates to a method of treating leukemia using rice prolamin, comprising administering a daily dose of isolated prolamin to a patient suffering from leukemia for a period of time from 5 days to 10 days. For the treatment application, the rice prolamin can stimulate human peripheral blood mononuclear cell (PBMC) to produce cytokines, such as tumor necrosis factor-alpha, to inhibit growth of and induce differentiation of human leukemia cells. The rice prolamin is gluten-free, thus will not trigger gastrointestinal allergic reaction, it also can decrease the tumor weight without changes in body weight and can inhibit the growth of peripheral blood leukocyte in leukemia mouse model.
Owner:MACKAY MEMORIAL HOSPITAL
Preparation method for nasopharynx cancer chemoradiotherapy assisting skin ointment
InactiveCN104288407AReduce tumor weightImprove tumor inhibition rateOintment deliveryDermatological disorderRed CloverGleditsia triacanthos
The invention discloses a preparation method of a nasopharynx cancer chemoradiotherapy assisting skin ointment, and aims to solve the treatment problem of nasopharynx cancer. The preparation method is characterized by comprising the following steps: (1) extracting volatile oil from groundsel, acorus gramineus and polygonum multiflorum coarse powder for later use; (2) grinding Chinese honey locust and peach gum to form fine powder for later use; (3) conducting aqueous extraction on elsholtzia rugulosa, pungent litse flower, leycesteria formosa, rhizoma pinelliae (decocted in a bag), trifolium pratense, cassia twig and the dregs obtained in the step 1, and conducting vacuum concentration and drying to obtain a primary material; (4) heating sesame oil, adding pine needles to the heated oil, filtering the oil material, adding the primary material and the Chinese honey locust and peach gum powder to the oil material at 120 DEG C, cooling, spraying the volatile oil, mixing uniformly, and subpackaging to obtain the product. The clinical experiments show that the nasopharynx cancer chemoradiotherapy assisting skin ointment is synergetic with the chemotherapy, good in in curative effect, high in safety, and worthy of clinical application and popularization.
Owner:所俊强
Application of a kind of lychee grass water extract radiotherapy sensitizer
ActiveCN110302380BGrowth inhibitionEnhanced inhibitory effectAntineoplastic agentsRadiosensitized materialsLychee fruitMechanism of action
Owner:LUOHE MEDICAL COLLEGE
Antitumor application of apios americana flower ethanol extract
InactiveCN108392514AReduce tumor weightGood antitumor activityNatural extract food ingredientsAntineoplastic agentsNude mouseBody weight
The invention discloses antitumor application of an apios americana flower ethanol extract. The antitumor application is characterized in that subcutaneous area of a nude mouse is inoculated with a hepatoma carcinoma cell Huh7 to form a tumor; meanwhile, the intervention of the apios americana flower ethanol extract is performed, and change conditions of body weight of the nude mouse in the experiment process are monitored. After an intervention experiment is ended, a subcutaneous tumor is stripped off, the weight of the tumor is recorded and secretion conditions of cytokines in serum are monitored, so that the intervention of the apios americana flower ethanol extract has obvious antitumor effect.
Owner:ZHEJIANG UNIV
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