The invention discloses a compound oral solution containing pholcodine, prepared from, by weight, 4-6 arts of pholcodine, 6-8 parts of triprolidine, 2-4 parts of glutathione, 15-20 parts of radix isatidis, 5-12 parts of stevioside, 8-12 parts of artemisia apiacea, 4-10 parts of fresh ginger, 4-8 parts of andrographis paniculata, 4-8 parts of semen ziziphi spinosae, 2-6 parts of liquorice root, 1-2 parts of taurocholic acid, 2-4 parts of honey, 0.2-0.4 parts of Pu-erh tea extract, 0.2-0.4 parts of celery leaf extract, and 0.2-0.4 parts of blueberry extract; Compared with the prior technology, the compound oral solution has synergistic effect between the raw material components, the treatment effect is well with quick effect, the drug resistance is small, the medicinal safety is high, the side effect is small, the stability is good, the shelf life is long , which is easy to carry, the preparing process is simple, suitable for large-scale production and so on.