Traditional Chinese medicine composition and application as radiotherapy sensitizer
A composition and technology of traditional Chinese medicine, applied in the field of medicine, can solve the problems of unsatisfactory radiosensitizing drugs, high toxicity of sensitizer drugs, poor drug targeting, etc., and achieve good anticancer activity, easy availability of raw materials, and preparation simple effect
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Embodiment 1
[0020] Embodiment 1 Chinese medicine composition mixture of the present invention
[0021] Prescription: 10 parts of toad skin, 6 parts of mylabris, 10 parts of Panax notoginseng, 10 parts of leech, 20 parts of curcuma, 20 parts of wood beetle, 10 parts of pangolin, 15 parts of astragalus, 30 parts of coix seed, 5 parts of angelica, 10 parts of licorice.
[0022] Preparation method: Take the medicinal materials of the above weight components, add water 5 times the total weight of the medicinal materials, soak for 30 minutes, decoct twice for 2 hours each time, filter, combine the filtrates, and concentrate the filtrates under reduced pressure to a relative density of 1.1 The extract, the relative density is the test result at 60 degrees Celsius, add ethanol until the alcohol content is 75% (v / v), let it stand for 24 hours, take the supernatant, recover the ethanol to concentrate, add water to 1000ml, stir Mix evenly, sub-package, and sterilize with circulating steam for 35 min...
Embodiment 2
[0023] Embodiment 2 Chinese medicine composition tablet of the present invention
[0024] Prescription: 5 parts of toad skin, 6 parts of mylabris, 5 parts of Panax notoginseng, 10 parts of leech, 20 parts of curcuma, 20 parts of ground beetle, 5 parts of pangolin, 10 parts of astragalus, 20 parts of coix seed, 5 parts of angelica, and 5 parts of licorice.
[0025] Preparation method: Take each medicinal material of the above weight components, add water 10 times the total weight of the medicinal materials, soak for 60 minutes, decoct once, 1 hour each time, filter, combine the filtrate, and concentrate the filtrate under reduced pressure to a relative density of 1.25 The extract, the relative density is the test result at 60 degrees Celsius, add ethanol until the alcohol content is 80% (v / v), let it stand for 24 hours, take the supernatant, recover the ethanol until concentrated, vacuum dry, and prepare Granules, ready to be compressed into tablets.
Embodiment 3
[0026] Embodiment 3 Chinese medicine composition capsule of the present invention
[0027] Prescription: 10 parts of toad skin, 8 parts of mylabris, 10 parts of Panax notoginseng, 15 parts of leech, 30 parts of curcuma, 30 parts of wood beetle, 10 parts of pangolin, 15 parts of astragalus, 30 parts of coix seed, 15 parts of angelica, 15 parts of licorice.
[0028] Preparation method: Take the medicinal materials of the above weight components, add water 8 times the total weight of the medicinal materials, soak for 45 minutes, decoct 4 times for 1.5 hours each time, filter, combine the filtrate, and concentrate the filtrate under reduced pressure to a relative density of 1.2 The extract, the relative density is the test result at 60 degrees Celsius, add ethanol until the alcohol content is 90% (v / v), let it stand for 24 hours, take the supernatant, recover the ethanol to concentrate, vacuum dry, and prepare Capsules, ready to pack into capsules.
[0029] The second part, the p...
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