Chinese medicinal preparation for treating secretory otitis media and preparation method thereof
The technology of a traditional Chinese medicine preparation and medicinal material is applied to the traditional Chinese medicine preparation for treating secretory otitis media and the preparation field thereof, which can solve the problems of large toxic and side effects, frequent morbidity in children, adverse effects on children's growth, etc., and achieve the effect of exact curative effect and small toxic and side effects.
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[0036] The present invention also provides a preparation method of the above-mentioned Chinese medicine preparation, the dosage form of the Chinese medicine preparation is a tablet, and the preparation method includes the following steps:
[0037] The first step: the raw materials of the traditional Chinese medicine preparation are mixed in proportion, 5-9 times the mass of the mixture is added with ethanol with an alcohol concentration of 80-90%, heated to reflux for 1 to 3 hours, extracted, and filtered to obtain the first extraction The dregs obtained by filtration are added with ethanol with an alcohol concentration of 80-90%, which is 2 to 5 times the mass of the dregs, heated and refluxed for 1 to 2 hours, and then extracted and filtered to obtain a second extract. Combine with the second extract, concentrate under reduced pressure to remove the ethanol solvent, and dry to obtain a dry paste;
[0038] The second step: the dry paste obtained in the first step is placed in an u...
Embodiment 1
[0044] Example 1: Tablet
[0045] Take horned snails 200g, short-petal female snails 350g, lotus leaf 250g, yellow scorpion 200g, golden hairpin 150g, scorpion leaf kalanchoe 280g, zulchi 160g, apricot fragrant rabbit ear wind 230g, partridge foot 80g, smelly Dan 220g, dung Jidu 120g, Hutonglei 150g, Jiulong Tuzhu 150g, Inverted Red Umbrella 160g, Shenghong Thistle 120g and Mengzi Wood Blue 210g;
[0046] Prepare according to the following steps:
[0047] The first step: the raw materials of the traditional Chinese medicine preparation are mixed in proportion, and ethanol with an alcohol concentration of 90% relative to the mass of the mixture is added, heated to reflux for 2 hours, extracted, filtered to obtain the first extract, and filtered to obtain the medicine Add ethanol with 90% alcohol concentration 3 times the mass of the dregs to the residue, heat reflux for 1 hour, extract and filter to obtain a second extract, combine the first extract with the second extract, and conce...
Embodiment 2
[0050] Example 2: Granules
[0051] Take the horn shells 170g, the short-petal female snails 300g, the lotus leaf money 210g, the yellow scorpion 130g, the golden hairpin 120g, the sporphyllum kalanchoe 180g, the zulbul 140g, the apricot fragrant rabbit ear wind 200g, the partridge foot 60g, the smell Dan 200g, Dung Jitu 100g, Hu Tonglei 110g, Jiulong Tuzhu 120g, Inverted Red Umbrella 140g, Shengli Thistle 100g and Mengzi Wood Blue 170g;
[0052] Prepare according to the following steps:
[0053] The first step: mix the raw materials according to the stated proportions, add 5 times the alcohol concentration of 90% ethanol to the mixture, heat to boil and reflux for 4 hours, filter, and use percolation at a rate of 2ml per minute. Slowly permeate, collect the percolate, and then concentrate it to a paste with a relative density of 1.08 at 70°C under a vacuum of 0.07Mpa, and spray dry. The inlet air temperature of the spray dryer is 175°C and the outlet air temperature is 85°C. Then ...
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