Method for extracting hesperidin in dried tangerine or orange peel by using enzymolysis approach

Abstract

The invention provides a method for extracting hesperidin in dried tangerine or orange peel by using an enzymolysis approach and relates to the field of medicines. Because citrus and other peels are enriched in pectin, and dissolution of active ingredients in cells is hindered by the pectin. According to the method disclosed by the invention, the pectin between cell walls of medicinal materials and cells is subjected to enzymolysis by adopting pectinase, so that the cell wells are destroyed, the hesperidin is fully dissolved, and the aim of obviously improving the hesperidin extraction rate is achieved. The method can be used for extracting the hesperidin in medicinal materials such as the dried tangerine or orange peel, fructus aurantii and immature bitter orange. The method disclosed by the invention has the advantages that the operation is simple, organic solvent residues are avoided, the environmental pollution is avoided, special equipment is not needed, the production safety is high, large-scale enterprise production is promoted, and the like.

Description

technical field [0001] The invention provides a method for extracting hesperidin by enzymatic hydrolysis, and relates to the field of medicine. Background technique [0002] Hesperidin has the functions of reducing vascular fragility, lowering blood pressure, anti-allergy, and inhibiting tumors. It is clinically used as an adjuvant treatment for cardiovascular system diseases, and can also be used as a raw material for pharmaceuticals in the pharmaceutical industry. Hesperidin is also used as a natural antioxidant Used in the food and cosmetic industry. [0003] The traditional methods of extracting hesperidin from citrus peels are hot water extraction, alcohol reflux extraction, alkali extraction and acid precipitation. These methods all use chemical solvents to infiltrate and dissolve the active ingredients in the medicinal materials. Although they are simple and easy to operate, they have shortcomings such as incomplete extraction, causing some hesperidin to remain in th...

AI Technical Summary

Problems solved by technology

Although the extraction time of these two methods is short, the ultrasonic method is very noisy, and the microwave method has radiation. They have high requirements for extraction equipment, which limits their application in large-scale production of enterprises to a certain extent.