Device and method for measuring biomarker concentration based on spiral resistor

Abstract

A device for measuring a concentration of a biological marker based on a spiral resistor, comprising a biosensing module (10), a spectrum receiving module (20), a control module (30), a drive module (40), and a spiral track resistor (50). The biosensing module (10) is configured to receive and reflect a characteristic spectrum signal and combine antigens in the biological marker. The spectrum receiving module (20) is configured to receive the characteristic spectrum signal reflected by an optical receiving unit (101) and transmit the characteristic spectrum signal to the control module (30). The control module (30) is configured to control, according to the characteristic spectrum signal, the drive module (40) to drive a spiral track resistor (50) and the spectrum receiving module (20) to move, determine a displacement offset of a characteristic spectrum according to an output resistance of the spiral track resistor (50), and determine a concentration of the biological marker according to the displacement offset, wherein the spiral track resistor (50) is driven by the drive module (40) to move, and subsequently changes the output resistance of the spiral track resistor (50). Also disclosed is a corresponding measurement method, thus eliminating effects of an interference material and a type of the biological marker, and resulting in an increase in a precision of a concentration measurement of the biological marker.

Description

technical field [0001] The invention relates to the technical field of life and health, in particular to a biomarker concentration measurement device and method based on a spiral resistor. Background technique [0002] At present, the application of variable resistors has been very extensive, such as changing the characteristics of signal generators, dimming lights, starting motors or controlling its speed, etc. In the field of precision control and precision measurement, it is difficult for the existing variable resistors to meet the requirements of its accuracy; and for the measurement of the concentration of biomarkers, the method usually used is photometry. The component of the specimen is mixed with one or more test reagents, the concentration of the analyte is determined multiple times, thereby triggering a biochemical reaction, which causes a measurable change in the optical properties of the analyte, and the photometric method examines and utilizes light The attenua...

AI Technical Summary

Problems solved by technology

In the field of precision control and precision measurement, it is difficult for the existing variable resistors to meet the accuracy requirements; and for the measurement of the concentration of biomarkers, the method usually used is photometry. The component of the specimen is mixed with one or more test reagents, the concentration of the analyte is determined multiple times, thereby triggering a biochemical reaction, which causes a measurable change in the optical properties of the analyte, and the photometric method examines and utilizes light The attenuation that occurs when a flow passes through an absorbing and / or astigmatic medium, however, this method of measurement is susceptible to systematic errors due to the type of sample itself and the interfering substances it may contain , making the measurement of the concentration of biomarkers inaccurate

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