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Medicament preparation for promoting rehabilitation of patients suffering from geriatric cognitive disorders

A pharmaceutical preparation, a technology for cognitive impairment, applied in the field of traditional Chinese medicine, can solve the problems of inability to obtain curative effects, neuropathological changes, and a long course of disease, and achieve the effect of improving learning and memory ability and treating senile dementia.

Inactive Publication Date: 2015-08-26
ZIBO DINGLI PATENT INFORMATION CONSULTING CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the long course of AD is formed by the action of various pathogenic factors in different periods, which eventually leads to neuropathological changes and clinical manifestations of AD.
It is the complexity of AD, which is caused by multiple factors, that makes it impossible for any drug acting on a single target to achieve a satisfactory curative effect.

Method used

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  • Medicament preparation for promoting rehabilitation of patients suffering from geriatric cognitive disorders
  • Medicament preparation for promoting rehabilitation of patients suffering from geriatric cognitive disorders

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0011] The preparation of embodiment 1 oral liquid:

[0012] Take 20g of tung leaves, 15g of tobacco pot grass, 20g of pine pine, 22g of fenugreek root, 16g of Buddha belly flower, 18g of hundred eyes vine, 16g of Tibetan green fruit, 15g of water hemp leaf, 16g of red oak seed, 20g of chrysanthemum root, and horseshoe root 18g, 20g of the skin of Jujube juncea, mix them, add water to decoct twice, add water for the first time to 12 times the weight of the medicinal materials, decoct for 2 hours, add water for the second time to 10 times the weight of the medicinal materials, decoct for 2 hours, combine the decoction, Filter, the filtrate is concentrated to a relative density of 1.20 (65°C), add an appropriate amount of ethanol to make the alcohol content (volume fraction) reach 80%, stir, let stand for 24 hours, filter, and the filtrate recovers ethanol and concentrates to a relative density of 1.30 (65°C). ℃) to obtain a concentrated solution, add sucrose and water to obtain...

Embodiment 2

[0013] The preparation of embodiment 2 granules:

[0014] Take 20g of tung leaves, 15g of tobacco pot grass, 20g of pine pine, 22g of fenugreek root, 16g of Buddha belly flower, 18g of hundred eyes vine, 16g of Tibetan green fruit, 15g of water hemp leaf, 16g of red oak seed, 20g of chrysanthemum root, and horseshoe root 18g, 20g of the bark skin and mix, add water to decoct twice, first add water to 10 times the weight of the medicinal material, decoct for 2 hours, add water for the second time to 8 times the weight of the medicinal material, decoct for 2 hours, combine the decoction, Filter, the filtrate is concentrated to a relative density of 1.15 (65°C), add an appropriate amount of ethanol to make the alcohol content (volume fraction) reach 70%, stir, let stand for 24 hours, filter, and the filtrate recovers ethanol and concentrates to a relative density of 1.30 (65°C). °C) to obtain a concentrated solution, which was spray-dried, added with excipients, and prepared into...

Embodiment 3

[0015] The preparation of embodiment 3 tablet:

[0016] Take 20g of tung leaves, 15g of tobacco pot grass, 20g of pine pine, 22g of fenugreek root, 16g of Buddha belly flower, 18g of hundred eyes vine, 16g of Tibetan green fruit, 15g of water hemp leaf, 16g of red oak seed, 20g of chrysanthemum root, and horseshoe root 18g, 20g of the skin of Jujube juncea, mix them, add water to decoct twice, add water for the first time to 12 times the weight of the medicinal materials, decoct for 2 hours, add water for the second time to 10 times the weight of the medicinal materials, decoct for 2 hours, combine the decoction, Filter, the filtrate is concentrated to a relative density of 1.10 (65°C), add an appropriate amount of ethanol to make the alcohol content (volume fraction) reach 75%, stir, let stand for 24 hours, filter, reclaim the ethanol from the filtrate and concentrate to a relative density of 1.30 (65°C). ℃), to obtain a concentrated solution, which was spray-dried, added exc...

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Abstract

The invention belongs to a pharmaceutical preparation and particularly discloses a medicament preparation for promoting rehabilitation of patients suffering from geriatric cognitive disorders. The active ingredients contained in the medicament preparation are prepared from the following traditional Chinese medicinal materials in parts by weight through a water extraction and alcohol precipitation method: 20 parts of tung leaves, 15 parts of east-asia low meadowrue, 20 parts of herb of slenderleaf stonecrop, 22 parts of vitis bryoniifolia root, 16 parts of herb of chien briggsia, 18 parts of morinda parvifolia, 16 parts of terminalia chebula retz, 15 parts of pilea notata, 16 parts of seed kernels of castanopsis hystrix, 20 parts of chamaemelum nobile root, 18 parts of water-chestnut root and 20 parts of bigleaf fig bark. The medicament preparation is capable of improving the memory and learning abilities of the patients suffering from geriatric cognitive disorders, thereby promoting the rehabilitation of the patients suffering from geriatric cognitive disorders.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a pharmaceutical preparation for promoting rehabilitation of elderly patients with cognitive impairment. Background technique [0002] Senile dementia, also known as Alzheimer's Disease (AD), is a common degenerative disease of the central nervous system, with severe memory function and advanced cognitive dysfunction as the main clinical features, and can endanger patient life. At present, a variety of hypotheses put forward by scholars at home and abroad have made great progress in the basic research and clinical research of AD. However, the long course of AD is formed by the action of various pathogenic factors in different periods, which eventually leads to neuropathological changes and clinical manifestations of AD. It is the complexity of AD, which is caused by multiple factors, that makes it impossible for any drug acting on a single target to achieve...

Claims

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Application Information

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IPC IPC(8): A61K36/87A61P25/28
Inventor 田丽华
Owner ZIBO DINGLI PATENT INFORMATION CONSULTING CO LTD
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