Labdane-type diterpene compound and its preparation method and use

A technology of compounds and diterpenes, applied in the application field in the preparation of antitumor drugs, can solve the problems of few components and activities, etc.
CN104945362AInactive Publication Date: 2015-09-30HENAN LUOYANG BONESETTING MEDICINE SCI & TECH
3 Cites 7 Cited by

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
HENAN LUOYANG BONESETTING MEDICINE SCI & TECH
Publication Date
2015-09-30
Estimated Expiration
Not applicable · inactive patent

Smart Images

  • Figure 1
    Figure 1
  • Figure 2
    Figure 2
  • Figure 3
    Figure 3
Patent Text Reader

Abstract

The invention discloses a labdane-type diterpene compound. The labdane-type diterpene compound has a chemical structure shown in the following description. The invention relates to the field of natural drugs and concretely relates to the novel labdane-type diterpene compound in motherwort, a preparation method of the compound and a medical use of the compound in preparation of antitumor drugs. An external test proves that the novel labdane-type diterpene compound has effects of resisting cervical carcinoma, leukemia and breast cancer and can be used for preparing drugs for resisting cervical carcinoma, leukemia and breast cancer.
Need to check novelty before this filing date? Find Prior Art

Description

technical field

[0001] The invention relates to the field of natural medicines, in particular to a new helianthin-type diterpene compound, a preparation method and the application of the compound in the preparation of antitumor drugs. Background technique

[0002] Helenoid diterpenes are bicyclic diterpenes, with decahydronaphthalene as the core, including its demethylation, secondary cleavage and rearrangement compounds, and is a class of diterpenes with richer structural types. The most representative helianthin-type diterpenes are from Andrographis paniculata ( Andrographis panis ) and andrographolide (Andrographolide) isolated from Coleus forskohlii ( Coleus forskohlii ) obtained in Coleus (Forskolin). The former has good antibacterial and anti-inflammatory effects, and the latter can be used to strengthen the heart, antidepressant, relieve spasm and treat asthma. In recent years, a large number of new helianthane-type diterpenes have been discovered with rich struct...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More