Traditional Chinese medicinal preparation for treating chemotherapy-induced oral ulcer

Abstract

The present invention discloses a traditional Chinese medicinal decoction for treating chemotherapy-induced oral ulcer. The traditional Chinese medicine believes that oral ulcer belongs to the category of aphtha and canker sore. The common pathogenesis of chemotherapy-induced oral ulcer mostly comprises weakened body resistance, insufficient vital-qi, intolerance by nature, taste damage, transformation failure of spleen, spleen vacuity, blood dryness, outside wind-dryness evil, yin-yang deficiency, deficiency fire uprising and toxic heat accumulation. The invention selects traditional Chinese medicines including silverweed cinquefoil root, lucid ganoderma, rust-coloured crotalaria herb with root, beechey fig leaf, marsh orchis herb, scoparius, Stachys sieboldii Miq., engler abelia fruit or flower, wallich willow root, Cynanchum amplexicaule Hemsl., elecampane, Suchow mosla herb and nard, which are prepared into a soup. Clinical test proves the total efficiency reaching 95%, which is significantly better than 75% in the control group; and the curative effect is substantial.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition, in particular to a traditional Chinese medicine preparation for treating oral ulcers caused by radiotherapy and chemotherapy. Background technique [0002] Oral ulcers are one of the common toxic and side effects of cancer patients receiving chemotherapy and radiotherapy. The clinical manifestations are mainly local pain, mucosal erythema, erosion, and ulcers. Very few symptoms such as fever and fatigue may occur. Stomatitis caused by chemotherapy is more common. It occurs 5 days after chemotherapy, and generally lasts for about 7 days. It occurs mostly in the oral mucosa and left and right buccal mucosa. It can seriously affect the quality of life of patients, delay the treatment process, and even cause secondary systemic infection. Currently, the targets of cytotoxic chemotherapeutic drugs and radiation therapy in clinical use are tissue cells with rapid DNA proliferation and renew...

AI Technical Summary

Problems solved by technology

Therefore, when using chemotherapeutic drugs, especially methotrexate and local irradiation of maxillofacial tumors, it will almost inevitably damage the epithelial cells of the oral mucosa, leading to ulcers and secondary bacterial infections. Western medicine focuses on local symptomatic treatment of oral ulcers. Treatment is mainly oral administration of antibiotics and other drugs, but some patients may fail due to improper selection of antibiotics or the emergence of bacterial resistance

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