New application of a kind of pharmaceutical composition and its preparation
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- 陕西郝其军制药股份有限公司
- Publication Date
- 2019-05-17
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Abstract
Description
technical field
[0001] The invention belongs to the field of pharmaceutical preparations, and in particular relates to the application of a pharmaceutical composition and its preparation in the field of preparing medicines for treating chronic myeloid leukemia, polycythemia vera and essential thrombocythemia. Background technique
[0002] Chronic myelogenous leukemia, referred to as CML for short, is a cell line disease caused by malignant lesions at the level of pluripotent stem cells with acquired chromosomal abnormalities. Mature white blood cells gather in the bone marrow, inhibit the normal hematopoiesis of the bone marrow, and can spread throughout the body through the blood, leading to anemia, easy bleeding, infection, and organ infiltration in patients. The cause of the disease is still unclear, but it is believed that the Philadelphia chromosome is closely related to the disease, and about 90 to 95% of patients have the Philadelphia chromosome. Chronic myelogenous ...