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Medicine composition for treating sexual precocity and application of medicine composition

A composition and a therapeutic technology, applied in the field of medicine, can solve the problems of children's sexual and psychological development lag, unable to be accepted by children's family, learning and living difficulties, etc., and achieve the effects of safety, no toxic side effects, short course of treatment and obvious effect.

Inactive Publication Date: 2015-11-18
QINGDAO JINZHI HIGH NEW TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, due to early sexual development, the children's sexual and psychological development is relatively lagging behind, which can easily lead to various difficulties in learning and life.
[0003] Currently, gonadotropin-releasing hormone-mimicking agent (GnRHa) recommended internationally for the treatment of idiopathic precocious puberty in girls has proven curative effect (RizzoV, DeSanctisV, CorriasA. Suppl: 178121786.), but the price is expensive, about 2,000 yuan per month, which cannot be accepted by most families with children in China

Method used

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  • Medicine composition for treating sexual precocity and application of medicine composition

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Comparison scheme
Effect test

Embodiment 1

[0015] The preparation of embodiment 1 Chinese medicine granules

[0016] Prescription of herbal medicine: 1.4kg of raw land, 2.4kg of raw oyster, 1.0kg of agrimony, 1.0kg of seaweed, 1.2kg of August leaf, 1.2kg of gonggong leaf, 0.8kg of willow, 0.6kg of polygala, 0.6kg of Magnolia officinalis.

[0017] Preparation process: Weigh the raw materials of the above-mentioned Chinese medicinal materials of the prescribed amount, add 12 times the amount of water, soak for 15 hours, then decoct three times, decoct for 2 hours for the first time, filter out the medicinal liquid for use; add 10 times the amount of water for the second time , decocted for 1.5 hours, filtered out the medicinal solution for later use; added 8 times the amount of water for the third time, decocted for 1 hour, and filtered the medicinal solution for later use; combined three decoctions, filtered, and collected the filtrate; the filtrate was concentrated to a thick paste, Bake at low temperature for 7 hours ...

Embodiment 2

[0018] The preparation of embodiment 2 Chinese medicine granules

[0019] Prescription of herbal medicine: 1.7kg raw land, 2.6kg raw oyster, 1.3kg Agrimony, 1.3kg seaweed, 1.4kg August leaf, 1.4kg Gonggong leaf, 0.7kg Xiheliu, 0.7kg polygala, 0.7kg Magnolia officinalis.

[0020] Preparation process: Weigh the above-mentioned raw materials of Chinese herbal medicines in the prescribed amount, add 11 times the amount of water, soak for 16 hours, then decoct three times, decoct for 2 hours for the first time, filter out the medicinal liquid for use; add 9 times the amount of water for the second time , decocted for 1.5 hours, filtered out the medicinal solution for later use; added 8 times the amount of water for the third time, decocted for 1 hour, and filtered the medicinal solution for later use; combined three decoctions, filtered, and collected the filtrate; the filtrate was concentrated to a thick paste, Bake at low temperature for 8 hours to obtain dry cream powder; add au...

Embodiment 3

[0021] The preparation of embodiment 3 Chinese medicine granules

[0022] Herbal medicine prescription: raw land 1.3kg, raw oyster 2.2kg, agrimony 0.9kg, seaweed 0.9kg, August leaf 1.0kg, Gonggong leaf 1.0kg, willow 0.5kg, polygala 0.5kg, magnolia officinalis 0.5kg.

[0023] Preparation process: Weigh the raw materials of the above-mentioned Chinese medicinal materials of the prescribed amount, add 12 times the amount of water, soak for 14 hours, and then decoct three times, the first time is 1.5 hours, and filter out the medicinal liquid for use; the second time add 9 times the amount of Water, decoct for 1.2 hours, filter out the medicinal liquid for later use; add 8 times the amount of water for the third time, decoct for 1 hour, and filter out the medicinal liquid for later use; combine the three decoctions, filter, and collect the filtrate; concentrate the filtrate to a thick paste , baked at low temperature for 7 hours to obtain dry cream powder; add auxiliary materials ...

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Abstract

The invention discloses a medicine composition for treating sexual precocity and application of the medicine composition. The medicine composition is prepared by the following Chinese crude drugs in part by weight: 11-17 parts of dried rhizome of rehmannia, 18-30 parts of raw oyster, 8-13 parts of hairyvein agrimony, 8-13 parts of marine alga, 9-16 parts of fiveleaf akebia fruit, 9-16 parts of Chinese holly leaves, 5-10 parts of Chinese tamarisk tops, 4-8 parts of polygala roots and 4-8 parts of Flos Magnoliae Officinalis. The medicine composition has effects of nourishing kidney-yin and reducing ministerial fire; when the medicine composition is used for treating sexual precocity, signs and symptoms can be improved effectively; the medicine composition is suitable for treating sexual precocity of girls suffering from low-grade or medium-grade sexual precocity; a clinical therapeutic effect is obvious and course of treatment is short; and the medicine composition takes effect quickly, is safe and does not have toxic or side effects.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a medicinal composition for treating precocious puberty and its application. Background technique [0002] Precocious puberty is one of the diseases of abnormal sexual development in children, and its incidence has increased significantly in recent years. Among them, idiopathic precocious puberty accounts for 80% to 90% of girls' true precocious puberty (KaplanSL, Grumbach MM. Clinical review 14: Pathophysiology and treatment of sexual precocity [J]. J Chin Endocrinol Metab, 1990, (71): 7852789.). Due to early puberty, the hypothalamus-pituitary-gonadal axis starts early, leading to premature appearance of sexual characteristics, early menstruation, and early physical development and accelerated bone growth. Without intervention, the bone age of a considerable number of children is significantly earlier than the actual age. , The epiphysis closes prematurely, result...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/804A61P15/00A61K35/618
Inventor 不公告发明人
Owner QINGDAO JINZHI HIGH NEW TECH
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