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Traditional Chinese medicine composition with the effects of improving sleep and enhancing immunity and its preparation method and application

A technology for enhancing immunity and improving sleep, which can be used in drug combinations, medical preparations containing active ingredients, and pharmaceutical formulas, etc., can solve the problems of unclear effect of melatonin in improving sleep, drug dependence, toxic and side effects, etc. Rigorous medication, no toxic side effects, and the effect of improving sleep

Active Publication Date: 2018-05-08
雷允上药业集团有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Hypnotics commonly used clinically at present include benzodiazepines, barbiturates and other non-barbiturates. The effect of treating insomnia is relatively obvious, but it has a greater impact on the liver and kidney, and users are prone to drug reactions. Dependence, usually increasing the dosage of medicine to maintain the effect, but also produce a lot of toxic side effects, so it is not suitable for long-term use of drugs
The effect of melatonin on improving sleep is not yet clear. Long-term or high-dose melatonin may cause harm to the human body, such as significantly inhibiting the function of the human reproductive system

Method used

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  • Traditional Chinese medicine composition with the effects of improving sleep and enhancing immunity and its preparation method and application
  • Traditional Chinese medicine composition with the effects of improving sleep and enhancing immunity and its preparation method and application
  • Traditional Chinese medicine composition with the effects of improving sleep and enhancing immunity and its preparation method and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0057] Chinese medicine composition oral liquid of the present invention

[0058] 1. Raw material parts by weight

[0059] Acanthopanax 2 parts, American ginseng 1 part, jujube seed 10 parts, Polygonatum 6 parts, psoraleae 3 parts, Poria cocos 10 parts.

[0060] 2. Preparation steps

[0061] (1) Get the American ginseng, Acanthopanax, and Psoraleae, add 50% ethanol (volume concentration) of 5 times the weight of the medicinal materials, heat and reflux to extract 2 times, each 2 hours, merge to obtain the alcohol extract; ethanol recovery ;

[0062] (2) Take the dregs extracted with ethanol in step (1) and add 10 times the amount of water, heat and decoct for 2 hours each time, and combine to obtain the water extract;

[0063] (3) Concentrate the alcohol extract to no ethanol smell, the equivalent of the medicinal material (relative to the alcohol extraction part) is about 1:1, the water extract is concentrated to the equivalent of about 0.8:1, mix with the alcohol extracti...

Embodiment 2

[0067] Chinese medicine composition granule of the present invention

[0068] 1. Raw material parts by weight

[0069] Acanthopanax 4 parts, American ginseng 2 parts, jujube seed 30 parts, Polygonatum 10 parts, psoraleae 8 parts, Poria cocos 30 parts.

[0070] 2. Preparation steps

[0071] (1) Take the above-mentioned American ginseng, Acanthopanax, and psoralen, add 60% ethanol in an amount 8 times the weight of the medicinal materials, heat and reflux for extraction twice, each time for 1 hour, and combine to obtain an alcohol extract; ethanol recovery;

[0072] (2) Take the dregs extracted with ethanol in step (1) and add 8 times the amount of water to Suanzaoren, Rhizoma Polygonatum and Poria Cocos, heat and decoct to extract 2 times, each time for 1 hour, and combine to obtain the water extract;

[0073] (3) Concentrate the alcoholic extract to no ethanol smell, the medicinal material equivalent (relative to the alcohol extraction part) is about 0.8:1, the water extract...

Embodiment 3

[0076] Chinese medicine composition capsule of the present invention

[0077] 1. Raw material parts by weight

[0078] Acanthopanax 4 parts, American ginseng 8 parts, jujube seed 20 parts, Polygonatum 16 parts, psoralen 2 parts, Poria cocos 10 parts.

[0079] 2. Preparation steps

[0080] (1) Take the above-mentioned American ginseng, Acanthopanax, and psoralen, add 80% ethanol in an amount 10 times the weight of the total medicinal materials, heat and reflux for extraction twice, each time for 2 hours, and combine to obtain an alcohol extract; ethanol recovery;

[0081] (2) Take the step (1) to extract the dregs of the medicine with ethanol, add 5 times the amount of water to the jujube seed, sealwort, and poria cocos, heat and extract 2 times, each time for 2 hours, and combine to obtain the water extract;

[0082] (3) Concentrate the ethanol extract until it has no ethanol smell, the medicinal material equivalent (relative to the alcohol extraction part) is about 1:1, the...

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Abstract

The invention discloses a traditional Chinese medicine composition capable of improving sleep and enhancing immunity, a preparation method and application thereof. The traditional Chinese medicine composition for improving sleep and enhancing immunity provided by the invention is made from Acanthopanax Radix, American Ginseng, Jujube Seed, Rhizoma Polygonatum, Psoraleae and Poria. The animal function test results prove that the traditional Chinese medicine composition provided by the invention has the functions of improving sleep and enhancing immunity, and the animal safety test results show that the traditional Chinese medicine composition of the invention is safe, has no toxic or side effects, and has no teratogenic and mutagenic effects. The human food test shows that the traditional Chinese medicine composition of the invention can effectively improve symptoms such as insomnia and low immunity, and the effect is remarkable, and it can be applied to the preparation of medicines or health care products, and has broad market prospects.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine compositions of medicines or health products, in particular to a traditional Chinese medicine composition capable of improving sleep and enhancing immunity, its preparation method and application. Background technique [0002] Sleep is a spontaneous and reversible resting state that occurs periodically in higher vertebrates, manifested as a decrease in the body's response to external stimuli and a temporary interruption of consciousness. About 1 / 3 of a person's life is spent in sleep. When people are in a sleep state, people's brains and bodies can be rested, rested and recovered, and an appropriate amount of sleep is helpful for people's daily work and study. Scientifically improving sleep quality is the guarantee for people's normal work, study and life. Sleep disorder refers to the abnormality of sleep quantity and sleep quality, or certain clinical symptoms occur during sleep, suc...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8969A61P37/04A61P25/20
Inventor 叶华王恒斌李全孙翔祝倩倩罗年翠王亦周
Owner 雷允上药业集团有限公司
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