Medical application of a genistein chromium complex in the treatment of diabetes

A technology of lignochromium and complexes, which is applied in the field of medicine and pharmacy, can solve problems such as no application reports of lignochromium complexes, and achieve the effects of reducing toxicity, improving hypoglycemic activity, and good hypoglycemic effect

Active Publication Date: 2017-12-08
BEIJING UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] There is no report on the application of the genistein chromium complex in the prevention and treatment of diabetes

Method used

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  • Medical application of a genistein chromium complex in the treatment of diabetes
  • Medical application of a genistein chromium complex in the treatment of diabetes
  • Medical application of a genistein chromium complex in the treatment of diabetes

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0073] The genistein chromium complex can be used as an active ingredient to prepare any pharmaceutical medicine for treating type II diabetes.

[0074] Take 300g of genistein chromium complex, add appropriate amount of starch, mix well, dry below 60°C, pack 1000 capsules, and obtain the capsule preparation of this product. This project complies with the relevant requirements of the capsule project of the Pharmacopoeia of the People's Republic of China 2000 Edition.

Embodiment 2

[0076] Take 500 g of genistein chromium complex, add appropriate amount of starch and lubricant, mix well, dry below 60°C, and press into tablets to obtain 1000 tablets. This project complies with the relevant requirements of the Pharmacopoeia of the People's Republic of China 2000 Edition tablet project.

Embodiment 3

[0078] Take 800g of genistein chromium complex, add appropriate amount of starch, mix well, dry below 60°C, and granulate to obtain 1000 bags of granules. This project complies with the relevant requirements of the 2000 edition of the Pharmacopoeia of the People's Republic of China.

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PUM

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Abstract

The invention provides medical application of a genistein chromium complex to treatment of diabetes. Results of the animal growth condition research, fasting blood-glucose value determination, glucose tolerance test, insulin tolerance test show that the genistein chromium complex has an excellent hypoglycemic effect, and can be used for preparing drugs for treating diabetes II; by combing the hypoglycemic advantage of chromium, the hypoglycemic activity of genistein is improved obviously and toxicity of inorganic chromium can be reduced.

Description

technical field [0001] The invention discloses the medical application of a genistein chromium complex in treating diabetes, relates to a compound used for treating diabetes, and belongs to the technical field of medicine and pharmacy. Background technique [0002] Genistein is a flavonoid compound with various biological activities, chemically named as 5,7,4'-trihydroxyisoflavone, widely found in soybeans, clover, gorse, acacia, and sophora Among traditional medicinal plants, it has high medicinal value. [0003] Molecular formula of genistein chromium complex: [C 15 h 9 o 5 ] 3 Cr•2H 2 O; molecular weight: 895.5; named: genistein chromium complex; structural formula: [0004] [0005] There is no report on the application of the genistein chromium complex in the prevention and treatment of diabetes. Contents of the invention [0006] The invention provides the medical application of the genistein chromium complex in treating diabetes, which can obviously improv...

Claims

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Application Information

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Patent Type & AuthorityPatents(China)
IPC IPC(8): A61K31/555A61P3/10
Inventor徐暾海李朋收刘铜华徐雅娟解生旭张曼祺
OwnerBEIJING UNIV OF CHINESE MEDICINE