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Pharmaceutical composition for treating nausea and vomiting caused by anaesthesia

A technology of nausea and vomiting, composition, applied in the direction of drug combination, medical raw materials derived from echinoderms, pharmaceutical formulations, etc., can solve the problems of long duration, extrapyramidal reaction, delayed recovery from anesthesia, etc., and achieves significant curative effect, safety and no toxic side effects

Inactive Publication Date: 2015-12-30
闫华
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] (2) Antihistamines: In addition to promethazine, antihistamines mainly act on the vestibular system and have little effect on chemoreceptor sensitive areas. Promethazine is an effective preventive antiemetic drug, but it can cause Delayed recovery from anesthesia, especially in elderly patients, can still cause dry mouth and delirium
The effects of droperidol and haloperidol are similar, with slow onset and long duration, and their side effects can cause extrapyramidal reactions, hypotension and sedation, etc.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] A pharmaceutical composition for treating nausea and vomiting caused by anesthesia, which is composed of the following traditional Chinese medicine raw materials in the following weight ratio: 5g of Chinese herbal medicine, 10g of daidaihua, 10g of lemon leaves, 5g of longan longan, 4g of fudicai, 4g of ground pepper 5g, Catalpa bark 7g, Gingergrass 8g, Cisanjia 8g, Cape japonica 9g, water keel 10g, bamboo leaf ginseng 5g, sea plate car 5g, hundred eyes vine 4g, nanmuxiang 5g, pomelo peel 6g, Vitex japonica 5g.

Embodiment 2

[0034] A pharmaceutical composition for the treatment of nausea and vomiting caused by anesthesia, which consists of the following traditional Chinese medicine raw materials in the following weight ratio: 6g of Chinese herbal medicine, 9g of daidaihua, 13g of lemon leaves, 4g of longan longan, 4g of fudicai, 4g of ground pepper 3g, Catalpa bark 5g, Gingergrass 10g, Echinacea 9g, Pomegranate 10g, Water keel 8g, Bamboo leaf ginseng 3g, Haipanche 6g, Hundred eyes vine 5g, Nanmuxiang 4g, Pomelo peel 7g, Vitex japonica 3g.

Embodiment 3

[0036] A pharmaceutical composition for the treatment of nausea and vomiting caused by anesthesia, which consists of the following traditional Chinese medicine raw materials in the following weight ratio: 7g of Chinese herbal medicine, 9g of daidaihua, 12g of lemon leaves, 7g of longan longan, 5g of fudicai, 5g of ground pepper 2g, Catalpa bark 6g, Gingergrass 9g, Echinacea 10g, Pomegranate 5g, Water keel 15g, Bamboo leaf ginseng 6g, Haipanche 3g, Hundred eyes vine 3g, Nanmuxiang 8g, Pomelo peel 5g, Vitex japonica 4g.

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PUM

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Abstract

A related pharmaceutical composition for treating nausea and vomiting caused by anaesthesia is composed of the following traditional Chinese medicine raw materials in parts by weight: 5-8 parts of Indian rorippa herb, 8-10 parts of daidaihua, 10-15 parts of lemon leaf, 3-7 parts of fructus piperis longi, 3-5 parts of all-grass of pedunculate trigonotis, 2-5 parts of mongollian thyme herb, 5-8 parts of root-bark of ovate catalpa, 7-10 parts of twoflower micromeria, 8-10 parts of trifoliate acanthopanax root or root-bark, 5-10 parts of galium verum L., 5-15 parts of Japanese polypody rhizome, 3-7 parts of root and rhizome of canton fairybells, 3-7 parts of asterias rollestoni bell and asterias amurensis lutken, 2-5 parts of littleleaf indianmulberry, 4-8 parts of Yunnan dutchmanspipe rhizome, 2-7 parts of pummelo pericarp, and 2-5 parts of fructus viticis negundo. The pharmaceutical composition possesses efficacies of pacifying liver and regulating qi, warming middle to harmonize stomach, clearing heat and detoxifying, promoting digestion and stopping vomit, is substantial in curative effect on nausea and vomiting caused by anaesthesia, and is safe and free of toxic and side effects.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine, in particular to a pharmaceutical composition for treating nausea and vomiting caused by anesthesia. Background technique [0002] Nausea and vomiting after surgery are related to the patient's condition, surgery and anesthesia. Statistics show that women are significantly higher than men, which may be related to the elevated levels of estrogen and progesterone in the plasma of adult female patients, while there is no such difference between male and female children; the probability of PONV in children is higher than that in adults, especially school-age children The highest; the incidence rate of people over 70 years old is significantly lower than that of young people, which is related to the inactivity of various reflexes in the elderly; obese patients are higher than ordinary adults, because more inhaled anesthetic drugs are accumulated in adipose tissue and more drugs are left in ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/896A61P1/08A61K35/616
Inventor 闫华徐素萍
Owner 闫华
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