Traditional Chinese medicine composition for improving intestinal cancer cachexia and preparation method of traditional Chinese medicine composition

A composition and cachexia technology, applied in the direction of drug combination, pharmaceutical formula, medical preparations containing active ingredients, etc., can solve the problems of increased drug resistance, serious side effects, and aggravated disease, so as to relieve progressive decline and improve muscle Atrophy, prolonging the effect of survival

Inactive Publication Date: 2016-01-06
季旭明
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] In the process of treating intestinal cancer with western medicine, the clinical use of chemotherapy is quite common, resulting in an increase in drug resistance year by year, and the side effects of chemotherapy are also very serious, which not only does not benefit the improvement of the condition, but may also aggravate the condition. quality of life has become a daunting task for China and the world

Method used

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  • Traditional Chinese medicine composition for improving intestinal cancer cachexia and preparation method of traditional Chinese medicine composition
  • Traditional Chinese medicine composition for improving intestinal cancer cachexia and preparation method of traditional Chinese medicine composition
  • Traditional Chinese medicine composition for improving intestinal cancer cachexia and preparation method of traditional Chinese medicine composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0040] The formula of the traditional Chinese medicine composition is: 25 parts of astragalus, 22 parts of Codonopsis pilosula, 35 parts of curcuma, 20 parts of white lentils, 18 parts of raw barley, 15 parts of honeysuckle, 6 parts of fried Atractylodes macrocephala, and 6 parts of tangerine peel.

[0041] The preparation method is:

[0042] (1) Mix astragalus, codonopsis, curcuma, white lentils, raw barley, honeysuckle, fried Atractylodes macrocephala, and tangerine peel, extract 3 times with 80 wt% ethanol that is 8 mass times of them, each time for 1.5 hours, and combine the extracts;

[0043] (2) Concentrate the extract into a clear or thick paste with a relative density of 1.20 to 1.40 at 80°C, and dry to obtain a dry paste;

[0044] (3) Grinding the dry paste into fine powder, adding medicinal amount of auxiliary materials, and making the traditional Chinese medicine composition into dosage forms such as tablets, capsules, granules, and pills.

Embodiment 2

[0046]The formula of the traditional Chinese medicine composition is: 20 parts of astragalus, 30 parts of Codonopsis pilosula, 30 parts of curcuma, 25 parts of white lentils, 15 parts of raw barley, 20 parts of honeysuckle, 5 parts of fried Atractylodes macrocephala, and 10 parts of tangerine peel. The preparation method is the same as in Example 1.

Embodiment 3

[0048] The formula of the traditional Chinese medicine composition is: 35 parts of astragalus, 20 parts of Codonopsis pilosula, 40 parts of curcuma, 15 parts of white lentils, 20 parts of raw barley, 10 parts of honeysuckle, 10 parts of fried Atractylodes macrocephala, and 5 parts of tangerine peel. The preparation method is the same as in Example 1.

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Abstract

The invention discloses a traditional Chinese medicine composition for improving intestinal cancer cachexia and a preparation method of the traditional Chinese medicine composition. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 20-35 parts of astragalus membranaceus, 20-30 parts of codonopsis pilosula, 30-40 parts of curcuma zedoary, 15-25 parts of white hyacinth beans, 15-20 parts of raw semen coicis, 10-20 parts of honeysuckle, 5-10 parts of roasted rhizoma atractylodis macrocephalae and 5-10 parts of pericarpium citri reticulatae. The traditional Chinese medicine composition is simple to prepare, plays roles in well carrying out whole regulation, improving cachexia muscle atrophy, suppressing muscle proteolysis, relieving and resisting progressive weight loss of cachexia, improving the survival quality of a patient, prolonging the life of the patient through collaborative working of the raw materials, and has a good effect on prevention and intervention of intestinal cancer cachexia.

Description

technical field [0001] The invention relates to a medicine for improving the quality of life of cancer cachexia patients, in particular to a traditional Chinese medicine composition for improving intestinal cancer cachexia and a preparation method thereof, belonging to the technical field of medicine. Background technique [0002] Cachexia is a medical term derived from the Greek words "kakos" and "hexis," which literally means "bad condition." Clinically, cachexia is defined as a syndrome with anorexia, anemia, and weight loss as the main symptoms. It can occur in a variety of diseases, including tumors, AIDS, severe trauma, post-operation, malabsorption, and severe sepsis. The most common cachexia associated with tumors is called tumor cachexia. [0003] Cancer cachexia occurs in more than 80% of patients with advanced intestinal cancer, which seriously affects the quality of life of patients, shortens the survival period, reduces the sensitivity of chemotherapy or treatm...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61P35/00
Inventor 季旭明刘凯张秋红吴海良张洪星
Owner 季旭明
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