Traditional Chinese medicine drug for treating polycystic ovarian syndrome

A polycystic ovary syndrome technology, applied in the field of drugs for the treatment of polycystic ovary syndrome, can solve the problems affecting blastocyst implantation, low pregnancy rate, and low egg quality, so as to reduce androgen levels and restore ovulation function , alleviating the inhibitory effect

Inactive Publication Date: 2016-01-20
庄小侃
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  • Abstract
  • Description
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Problems solved by technology

The contraceptive pill (OCP) Diane-35 is the drug of choice for hyperandrogenism and increased LH / FSH ratio in the pathogenesis of PCOS with less side effects; clomiphene citrate (CC) is the drug of choice for inducing ovulation, but due to CC competes with endometrial target cell estrogen receptors, blocks the stimulating effect of estrogen on the endometrium, makes endometrial glands dysplasia, and affects blastocyst implantation; in addition, some PCOS patients respond poorly to CC and cause egg quality Low or no response, ultimately leading to high ovulation and low pregnancy rate in CC treatment; while the second-line ovulation induction drug gonadotropin is for patients with PCOS, because the ovary is highly sensitive to gonadotropin stimulation, ovulation induction is not only difficult to control its development and The number of follicles released may also lead to multiple pregnancy and the risk of ovarian hyperstimulation syndrome (OHSS)

Method used

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  • Traditional Chinese medicine drug for treating polycystic ovarian syndrome

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preparation example Construction

[0052] The present invention also provides a preparation method of the above-mentioned traditional Chinese medicine, specifically comprising:

[0053] The first step is to weigh the white quartz by weight and add water to fry for 1 to 3 hours. The amount of water added is 2 to 4 times its mass, and then add aconite, cinnamon, tortoise shell glue, dogwood, dodder, antler cream, and fried Atractylodes macrocephala according to the weight. , Poria cocos, Pinellia fragrans, Fructus chinensis, Radix Paeoniae Alba, Psoralen, Citrus aurantium, Radix Glycyrrhizae, add water 2 to 4 times the weight of these raw materials, decoct 1 to 3 times, Each time for 1 to 3 hours, filter, combine the filtrates, concentrate to a thick paste with a relative density of 1.05 to 1.20 at 80°C, add ethanol with an alcohol concentration of 80% that is 1 to 3 times the volume of the thick paste, mix well, and leave to stand. Set aside for 12 to 48 hours to precipitate, take the supernatant, recover ethano...

Embodiment 1

[0058] Embodiment 1 capsule 1

[0059] Weigh 15g of white quartz, add 50g of water and fry for 3 hours, then add 15g of aconite, 15g of cinnamon, 15g of tortoise shell glue, 20g of dogwood, 20g of dodder, 20g of antler cream, 15g of fried Atractylodes macrocephala, 25g of poria cocos, and 10g of pinellia , 20g of fennel, 15g of white peony, 15g of psoralen, 15g of citrus aurantium, 10g of roasted licorice, add 700g of water, decoct 3 times, 2 hours each time, filter, combine the filtrate, concentrate to 80 ℃ For the thick paste with a density of 1.10, add ethanol with an alcohol concentration of 80% that is twice the volume of the thick paste, mix well, let it stand for 24 hours to precipitate, take the supernatant, recover the ethanol, and dry it in an oven at 80°C Cool and crush into the first powder. Wash 15g Morinda officinalis, 20g Cistanche, 20g Rehmannia glutinosa, 15g medlar, 20g Salvia miltiorrhiza, and 15g angelica, respectively, wash, crush, and mix together, and us...

Embodiment 2

[0060] Embodiment 2 Capsule 2

[0061] Weigh 15g of white quartz by weight, add 50g of water and fry for 3 hours, then add 10g of aconite, 15g of cinnamon, 15g of tortoise shell glue, 20g of dogwood, 20g of dodder, 15g of antler cream, 15g of fried Atractylodes macrocephala, 20g of Poria cocos, and 10g of pinellia , 15g of fennel, 10g of white peony, 15g of psoralen, 10g of citrus aurantium, 10g of roasted licorice, add 700g of water, decoct 3 times, 2 hours each time, filter, combine the filtrate, concentrate to 80 ℃ For the thick paste with a density of 1.10, add ethanol with an alcohol concentration of 80% that is twice the volume of the thick paste, mix well, let it stand for 24 hours to precipitate, take the supernatant, recover the ethanol, and dry it in an oven at 80°C Cool and crush into the first powder. Wash 10g Morinda officinalis, 15g Cistanche, 15g Rehmannia glutinosa, 15g medlar, 20g Salvia miltiorrhiza, and 10g angelica, respectively, wash, crush, and mix togeth...

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Abstract

The invention provides a traditional Chinese medicine drug for treating polycystic ovarian syndrome. The traditional Chinese medicine drug is prepared from processed radix aconiti lateralis, cortex cinnamomi, morinda officinalis, cistanche, crystobalite, tortoise-plastron glue, prepared rehmannia roots, dogwood, dodder, fruits of Chinese wolfberry, cornu cervi degelatinatum, roasted rhizoma atractylodis macrocephalae, poria cocos, rhizoma pinellinae praeparata, salvia miltiorrhiza, angelica sinensis, motherwort fruits, radix paeoniae alba, fructus psoraleae, fructus aurantii and honey-fried licorice roots. The curative effect is remarkable, the androgen level can be effectively lowered, inhibition of follicular development is relieved, and the ovulation function is recovered.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a medicine for treating polycystic ovary syndrome. Background technique [0002] Polycystic ovary syndrome (polycysticovarysyndrome, PCOS) is a common endocrine disease in gynecological clinics, and the incidence rate can reach 5% to 10%. Among them, hyperandrogenism is its main endocrine feature. In patients with polycystic ovary syndrome, regardless of puberty or childbearing age, the androgen in the ovaries is too high, which inhibits follicular development and causes follicular atresia, resulting in oligoovulation or anovulation. The clinical manifestation is oligomenorrhea. , amenorrhea, or infertility after marriage; accompanied by hirsutism, hair loss, acne, obesity and other special diseases. The pathogenesis of polycystic ovary syndrome has the following three aspects: In recent years, many scholars have pointed out that polycystic ovary syndrome pa...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8888A61P15/08A61P5/28A61K35/32A61K35/586A61K33/00
Inventor 庄小侃
Owner 庄小侃
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