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Traditional Chinese medicine composition for treating AIDS and preparation method thereof

A composition and technology of traditional Chinese medicine, applied in the field of traditional Chinese medicine composition and its preparation for the treatment of AIDS, can solve the problems of delayed onset, unusable use by pregnant women, dependence on drug properties, etc., and achieve the effect of simple formula, significant effect and simple operation

Inactive Publication Date: 2016-01-20
INST OF TROPICAL BIOSCI & BIOTECH CHINESE ACADEMY OF TROPICAL AGRI SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The drugs currently on the market can only delay the onset of the disease and prolong the life of the infected person. The currently marketed drugs include nucleosides represented by azidothymidine (AZT) and non-nucleosides represented by delaviridine. Reverse transcriptase inhibitors, proteolytic enzyme inhibitors such as ritonavir, fusion inhibitor enfuvirtide and receptor inhibitor CCR5, these drugs can only prolong the lives of infected people, but cannot cure AIDS, and long-term use will cause drug dependence, while pregnant women also can not be used

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0036] The invention also provides a preparation method of the composition.

[0037] A preparation method of a traditional Chinese medicine composition. In parts by weight, 2-4 parts of bark bark, 2-5 parts of Schisandra chinensis, 2-5 parts of Ganoderma lucidum, 1-4 parts of ginger, 2-5 parts of Morinda officinalis, licorice 2-5 parts, extracted with water and filtered, the filtrate was concentrated and precipitated with ethanol, filtered, and the filtrate was collected.

[0038] Wherein, as preferably, the weight fraction of described crude drug is preferably:

[0039] 3 parts of Bairui Xiangpi, 3 parts of Schisandra, 3 parts of Ganoderma lucidum, 2 parts of ginger, 3 parts of Morinda officinalis, and 3 parts of licorice.

[0040]The water extraction method used in the preparation method of the present invention is a conventional extraction method in the art. Preferably, the water extraction in the preparation method of the present invention is water decoction extraction. ...

Embodiment 1

[0057] Embodiment 1: prepare the capsule of Chinese medicine composition of the present invention

[0058] Take each raw material (unit: g) by the following weight:

[0059] Bai Rui Xiang Pi 300, Schisandra 300, Ganoderma lucidum 400, Ginger 200, Morinda officinalis 300, Licorice 300;

[0060] Preparation method: decoct bark bark, Schisandra chinensis, ganoderma lucidum, ginger, Morinda officinalis and licorice with water 6 times the total weight of raw materials, decoct twice for 1 hour each time, filter, combine the filtrates filtered each time, Concentrate the filtrate to a relative density of about 1.10-1.15 (56°C) to obtain a concentrate, add ethanol to the concentrate to adjust the alcohol concentration (volume percentage) to 80%, refrigerate (0-10°C) for 24 hours, filter, and collect the filtrate The traditional Chinese medicine composition is obtained, after recovering the ethanol under reduced pressure, dry the extract under reduced pressure at a pressure of 0.06Mpa-...

Embodiment 2

[0061] Embodiment 2: prepare the tablet of Chinese medicine composition of the present invention

[0062] Take each raw material (unit: g) by the following weight:

[0063] Bai Rui Xiang Pi 300, Schisandra 200, Ganoderma lucidum 300, Ginger 200, Morinda officinalis 300, Licorice 200;

[0064] Preparation method: decoct bark bark, Schisandra chinensis, ganoderma lucidum, ginger, Morinda officinalis and licorice with water 3 times the total weight of raw materials for 3 times, decoct for 3 hours each time, filter, combine the filtrates filtered each time, Concentrate the filtrate to a relative density of about 1.10-1.15 (56°C) to obtain a concentrate, add ethanol to the concentrate to adjust the alcohol concentration (volume percentage) to 70%, refrigerate (0-10°C) for 24 hours, filter, and collect the filtrate The traditional Chinese medicine composition is obtained, after recovering the ethanol under reduced pressure, dry under reduced pressure at a pressure of 0.06-0.08Mpa a...

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PUM

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Abstract

The invention relates to the field of traditional Chinese medicines, and discloses a traditional Chinese medicine composition as well as a preparation method and application thereof. The traditional Chinese medicine composition is prepared from the following raw medicinal materials in parts by weight: 2-4 parts of bark of Korean daphne, 2-5 parts of Chinese magnoliavine fruit, 2-5 parts of lucid ganoderma, 1-4 parts of ginger, 2-5 parts of medicinal indianmulberry root and 2-5 parts of licorice root. The traditional Chinese medicine composition is simple in formula, and all the medicinal materials influence with one another to achieve a synergistic effect, so that the traditional Chinese medicine composition has significant effects of dispelling wind and dampness, warming and invigorating kidney yang, tonifying kidney to strengthen tendons, clearing away heat and toxic materials and the like, and can effectively relieve and treat AIDS virus infection and syndromes caused by the same. The preparation method of the traditional Chinese medicine composition provided by the invention comprises the following steps: mixing the bark of Korean daphne, the Chinese magnoliavine fruit, the lucid ganoderma, the ginger, the medicinal indianmulberry root and the licorice root according to certain proportions, performing water extraction, then filtering, concentrating the filtrate, then performing ethanol precipitation, then filtering, and collecting the filtrate. The active ingredients of each raw material are preserved to the utmost extent, and the prepared traditional Chinese medicine composition is significant in effect of treating AIDS, and is simple to operate and is suitable for industrial production at the same time.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition for treating AIDS and its preparation method and application. Background technique [0002] AIDS, also known as acquired immunodeficiency syndrome (acquiredimmune deficiency syndrome, AIDS), since its discovery in 1981, gradually began to enter people's field of vision. Due to the development of human society and the transformation of human thinking, AIDS has gradually evolved from a purely medical problem to a serious social problem. AIDS virus (Human Immunodeficiency Virus, HIV) is transmitted through sexual behavior, blood, mother and child, etc., and develops into a catastrophic infectious disease that can destroy human beings like smallpox and plague. According to the United Nations World Health Organization survey, there were more than 34 million HIV-infected people in the world in 2010, more than 2.7 million people wer...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9068A61P31/18
Inventor 赵友兴黄圣卓马青云王琪孔凡栋周丽曼戴好富
Owner INST OF TROPICAL BIOSCI & BIOTECH CHINESE ACADEMY OF TROPICAL AGRI SCI
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