A kind of medical alginate hydrogel and its production process and application

A technology of alginate and production process, which is applied in medical science, bandages, etc., can solve the problems that it can only be applied to the surface of wounded patients, easily cause allergies or secondary injuries, and cannot be biodegradable, so as to promote wound healing. Healing, remarkable effect, and safe effect

Active Publication Date: 2018-12-28
WUXI HENGCHENG MEDICAL TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Existing medical hydrogels are all liquid and cannot be molded in actual use. Therefore, they can only be filled in various types of packaging bags, such as medical cooling patches packaged in plastic bags, or When in use, it can only be applied to the surface of the injured patient. When it needs to be removed, the residue on the injured part must be cleaned, which brings inconvenience to use; at the same time, the existing medical hydrogels generally cannot achieve Biodegradable. The so-called biodegradable means that the hydrogel is generally composed of polymer compounds. After being attached to the surface of human wounds, it cannot be absorbed by human tissues, which may easily cause allergies or secondary injuries.

Method used

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Effect test

Embodiment Construction

[0024] A production process of medical alginate hydrogel, comprising the following steps:

[0025] Step 1: Prepare sodium alginate solution: Dissolve sodium alginate with a purity of 100% in distilled water; the ratio of sodium alginate to distilled water is 1:100 to 5:100; after a lot of experiments and calculations, the optimal ratio is 1 :100 or so, when it is lower than 1:100, the subsequent production speed will be accelerated, but the fiber removal speed and completeness of calcium alginate will be affected. In the final product, although it has been completely transparent and gelled, there will be some When the ratio is higher than 2:100, the calcium alginate is not easy to completely hydrate, and a white non-gelled non-woven fabric will appear in the final gel block, and the production speed is also seriously affected. Influence, process quality requirements are also stricter, when it is higher than 4:100, the production will become very difficult, when it reaches 5:10...

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Abstract

The invention discloses a medical alginate hydrogel, a production technology and applications thereof. The technology comprises the following steps: step one, dissolving sodium alginate with a purity of 100% into distilled water; step two, preparing calcium alginate nonwoven cloth with a purity of 100%; step three, soaking the calcium alginate nonwoven cloth into the sodium alginate solution until the fibers of the calcium alginate nonwoven cloth are completely removed so as to obtain transparent medical alginate hydrogel. The provided alginate hydrogel is prepared by mixing two alginate products; alginate is a biological product extracted from alga, has a self-bactericidal function, will not be adhered on the wounds, can form a wet growth environment on the wounds, has a high oxygen transmission rate, and can be biologically degraded. At the same time, the sodium ions are replaced by calcium ions, solid moulded transparent hydrogel is obtained, and the provided medical alginate hydrogel can be directly made into products containing hydrogel blocks according to the final requirements of products.

Description

technical field [0001] The invention relates to a medical alginate hydrogel, a production process and an application thereof. Background technique [0002] There are many types of medical hydrogels. Generally speaking, it is composed of deionized water plus some polymer copolymers and cross-linking agents to form a gel. Existing medical hydrogels are all liquid and cannot be molded in actual use. Therefore, they can only be filled in various types of packaging bags, such as medical cooling patches packaged in plastic bags, or When in use, it can only be applied to the surface of the injured patient. When it needs to be removed, the residue on the injured part must be cleaned, which brings inconvenience to use; at the same time, the existing medical hydrogels generally cannot achieve Biodegradable. The so-called biodegradable means that the hydrogel is generally composed of polymer compounds. After being attached to the surface of human wounds, it cannot be absorbed by huma...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61L26/00
CPCA61L26/0023A61L26/0066A61L26/008A61L26/009A61L2300/232A61L2300/30A61L2300/404C08L5/04
Inventor 王润宇韩士兵吕国忠赵朋高宏陆培华苏强
Owner WUXI HENGCHENG MEDICAL TECH CO LTD
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