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Resveratrol dry suspension and preparation method thereof

A technology of resveratrol and dry suspension, applied in the direction of anti-inflammatory agent, antidote, non-central pain reliever, etc., can solve the problem that resveratrol is insoluble in water, affects absorption and convenience, and application limitation and other problems, to achieve the effects of good drug content uniformity, simple preparation method and easy realization.

Inactive Publication Date: 2016-06-01
郭敏
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Resveratrol is insoluble in water and cannot be used after being dissolved in water, which affects its absorption and convenience after use, and limits its application

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] Embodiment 1: Resveratrol dry suspension and preparation method thereof

[0017] 1. Prescription: Resveratrol 1g, sodium carboxymethylcellulose 5g, ethanol 2g, starch lactose complex 50g, mannitol 44g.

[0018] 2. Preparation method: Weigh the prescribed amount of resveratrol, add the prescribed amount of solvent, and stir to dissolve the resveratrol completely to obtain a clear solution; add suspending agent, flavoring agent, and filler to the solution successively , stirred to make soft material; granulate the prepared soft material, pass through a 20-mesh sieve, dry at 60 degrees Celsius, and granulate through a 20-mesh sieve.

Embodiment 2

[0019] Embodiment 2: resveratrol dry suspension and preparation method thereof

[0020] 1. Prescription: 30g of resveratrol, 1g of sodium carboxymethylcellulose, 30g of ethanol, 9g of sucralose, 1g of strawberry essence, 35g of starch-lactose complex, 24g of mannitol.

[0021] 2. Preparation method: Weigh the prescribed amount of resveratrol, add the prescribed amount of solvent, and stir to dissolve the resveratrol completely to obtain a clear solution; add suspending agent, flavoring agent, and filler to the solution successively , stirred to make soft material; granulate the prepared soft material, pass through a 20-mesh sieve, dry at 60 degrees Celsius, and granulate through a 20-mesh sieve.

Embodiment 3

[0022] Embodiment 3: resveratrol dry suspension and preparation method thereof

[0023] 1. Prescription: Resveratrol 15g, sodium carboxymethylcellulose 3g, ethanol 20g, sucralose 4.9g, strawberry essence 0.1g, starch lactose complex 60g, mannitol 17g.

[0024] 2. Preparation method: Weigh the prescribed amount of resveratrol, add the prescribed amount of solvent, and stir to dissolve the resveratrol completely to obtain a clear solution; add suspending agent, flavoring agent, and filler to the solution successively , stirred to make soft material; granulate the prepared soft material, pass through a 20-mesh sieve, dry at 60 degrees Celsius, and granulate through a 20-mesh sieve.

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PUM

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Abstract

The invention discloses a resveratrol dry suspension and a preparation method thereof and belongs to the field of pharmaceutic preparations. The resveratrol dry suspension consists of a suspending aid, ethanol, corrigent and an auxiliary agent. The preparation method has the characteristics of simple preparation method, high sedimentation volume ratio, good in medicine content uniformity and the like, and is easily accepted by patients.

Description

technical field [0001] The invention belongs to the field of pharmaceutical preparations, and in particular relates to a resveratrol dry suspension and a preparation method thereof. Background technique [0002] Resveratrol, a phenolic phytoalexin found in grape skins and other plants, is loved for its anticancer, antioxidant, anti-inflammatory, and antibacterial properties, says Plant Sources. Because the French often drink high-fat foods containing resveratrol, the incidence of coronary heart disease in the French is lower than that in other western countries. From this information, we can know that resveratrol can effectively suppress the preventive effect of high fat. Some countries and regions have developed resveratrol and its products as dietary supplements. [0003] Resveratrol is insoluble in water and cannot be used after being dissolved in water, which affects its absorption and convenience after use, and limits its application. Contents of the invention [00...

Claims

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Application Information

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IPC IPC(8): A61K9/16A61K31/05A61P35/00A61P39/06A61P29/00A61P31/04
CPCA61K9/1652A61K31/05
Inventor 郭敏
Owner 郭敏
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