Albendazole dry suspension and preparation method thereof

A technology for dry albendazole and albendazole, which is applied in the field of veterinary drug preparations, can solve problems such as inability to administer through drinking water, albendazole preparations are insoluble in water, etc., and achieves good uniformity of drug content and simple preparation method. , easy to achieve effect

Inactive Publication Date: 2016-05-04
陈小媚
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In order to solve the problem that albendazole preparation is insoluble in water, the invention provides a kind of albendazole dry suspension, solves the technical problem that albendazole preparation is insoluble in water and cannot be administered by drinking water

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0013] Embodiment 1: Albendazole dry suspension and preparation method thereof

[0014] 1. Prescription: 2g of albendazole, 1g of sodium carboxymethylcellulose, 5ml of polyvinylpyrrolidone, and starch-lactose complex to the full amount.

[0015] Two, preparation method: take the albendazole of prescription quantity, add the solvent of prescription quantity, stir, make albendazole dissolve completely, obtain clear solution; Add suspending agent, auxiliary material successively in solution, stir, mix well , sieved, dried, and sieved again.

Embodiment 2

[0016] Embodiment 2: Albendazole dry suspension and preparation method thereof

[0017] 1. Prescription: Albendazole 10g, Arabic gum powder 10g, dimethylformamide 20ml, lactose to full amount.

[0018] Two, preparation method: take the albendazole of prescription quantity, add the solvent of prescription quantity, stir, make albendazole dissolve completely, obtain clear solution; Add suspending agent, auxiliary material successively in solution, stir, mix well , sieved, dried, and sieved again.

Embodiment 3

[0019] Embodiment 3: Albendazole dry suspension and preparation method thereof

[0020] 1. Prescription: Albendazole 6g, a mixture of sodium alginate and microcrystalline cellulose (sodium alginate:microcrystalline cellulose=2:8) 8g, a mixture of ethanol and glycerin (ethanol:glycerol=7:3) 15ml, mannitol to make up to the full amount.

[0021] Two, preparation method: take the albendazole of prescription quantity, add the solvent of prescription quantity, stir, make albendazole dissolve completely, obtain clear solution; Add suspending agent, auxiliary material successively in solution, stir, mix well , sieved, dried, and sieved again.

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PUM

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Abstract

The invention discloses an albendazole dry suspension and a preparation method thereof, and belongs to the field of veterinary medicine preparations. The albendazole dry suspension consists of a suspending aid, a solvent, and auxiliary materials. The albendazole dry suspension has the characteristics of simple preparation method, high sedimentation ratio, high medicinal content uniformity and the like, and can be easily accepted by patients.

Description

technical field [0001] The invention belongs to the field of veterinary drug preparations, and in particular relates to a dry suspension of albendazole and a preparation method thereof. Background technique [0002] Albendazole Albendazole is a broad-spectrum deworming drug with high efficiency and low toxicity. Insect effect is good, is widely used. [0003] Albendazole is insoluble in water and cannot be used after being dissolved in water, which affects its absorption and convenience after use and limits its application. Contents of the invention [0004] In order to solve the problem that the albendazole preparation is insoluble in water, the invention provides a dry suspension of albendazole, which solves the technical problem that the albendazole preparation is insoluble in water and cannot be administered through drinking water. The scheme of the present invention is specifically as follows: [0005] A kind of albendazole dry suspension, is made up of albendazole...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/14A61K31/4184A61P33/02A61P33/10
CPCA61K9/146A61K31/4184
Inventor 陈小媚
Owner 陈小媚
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