Medical composite dressing and preparation method thereof

A technology of mixed solution and carrier material, which is applied in the field of medical composite dressing and its preparation, can solve the problems of poor mechanical properties, inability to meet the complex needs of the wound healing process, poor absorption performance, etc., and achieve convenient operation, remarkable effect of promoting wound healing, keep moist effect

Inactive Publication Date: 2016-06-15
上海白衣缘生物工程有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Since the wound healing process is a complex process, different wounds and different stages of the same wound have different requirements for dressings, so currently no single material can meet the complex needs of the wound healing process
For example, most of the dressings made of natural materials have good absorption, good biocompatibility and biological activity, but poor mechanical properties; synthetic polymer materials have good insulation properties and good mechanical strength, but their absorption properties are relatively poor compared to natural materials some

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] (1) Preparation of carboxymethyl chitosan solution: Weigh 75g carboxymethyl chitosan, add 425g purified water, stir until dissolved, and prepare 15% carboxymethyl chitosan solution.

[0023] (2) Preparation of sesame oil / beeswax mixture: weigh 100g beeswax and 1000g sesame oil, mix them, heat and stir until the beeswax dissolves.

[0024] (3) Preparation of carboxymethyl chitosan solution, sesame oil and beeswax mixed solution: the 15% carboxymethyl chitosan solution prepared in step (1) and the prepared sesame oil / beeswax mixed solution in step (2), both Mix, heat, and stir well.

[0025] (4) Dip the spunlace non-woven fabric with a thickness of 0.5 mm into the mixture of carboxymethyl chitosan solution, sesame oil and beeswax, take it out after 5 minutes, pack it in an inner packaging bag, and finally sterilize it by irradiation.

Embodiment 2

[0027] (1) Preparation of carboxymethyl chitosan solution: Weigh 25 g of carboxymethyl chitosan, add 475 g of purified water, stir until dissolved, and prepare a 5% carboxymethyl chitosan solution.

[0028] (2) Preparation of sesame oil / beeswax mixture: weigh 200g beeswax and 1000g sesame oil, mix them, heat and stir until the beeswax dissolves.

[0029] (3) Preparation of carboxymethyl chitosan solution, sesame oil and beeswax mixed solution: the 5% carboxymethyl chitosan solution prepared in step (1) and the prepared sesame oil / beeswax mixed solution in step (2), both Mix, heat, and stir well.

[0030] (4) Immerse the spunlace non-woven fabric with a thickness of 2 mm into the mixture of carboxymethyl chitosan solution, sesame oil and beeswax, take it out after 10 minutes, package it in an inner packaging bag, and finally sterilize it by irradiation.

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Abstract

The invention discloses a medical composite dressing and a preparation method thereof. The medical composite dressing is made of fabrics such as non-woven fabrics or cotton fabrics as carrier materials, soaked in a mixture composed of carboxymethyl chitosan solution, sesame oil, and beeswax, taken out, packaged in inner packaging bags, and finally irradiated and sterilized. have to. The medical composite dressing has the following advantages: (1) Contains carboxymethyl chitosan, sesame oil and beeswax and other healing-promoting ingredients, which have a significant effect on promoting wound healing; (2) The carrier material endows the film dressing with a certain degree of flexibility and strength. , easy to peel and paste, easy to operate, no adhesion to the wound surface, no secondary damage; (3) It has the functions of keeping moist, antibacterial, and reducing scar formation. The medical composite dressing is a moist composite dressing that can significantly promote wound healing, and is suitable for the treatment of surgical wounds, abrasions, burns, skin donor sites, decubitus ulcers, diabetic ulcers and other difficult-to-heal wounds.

Description

technical field [0001] The invention relates to a medical composite dressing and a preparation method thereof, belonging to the field of biomedical materials. Background technique [0002] Trauma is the damage caused by normal skin (tissue) under the action of external injury factors. Common traumas include surgical incisions, abrasions, burns, donor sites, decubitus ulcers, vascular ulcers of lower extremities, diabetic ulcers, and other difficult-to-heal wounds. The formation and existence of wounds will have a significant impact on local and even systemic functions of the body. In order to accelerate the healing of the wound and reduce the infection of the wound surface, dressings are generally used to cover and protect the wound. [0003] An ideal medical dressing should have the following properties: (1) maintain a moist environment on the wound surface, which is conducive to wound healing; (2) can effectively absorb wound exudate and reduce infection; (3) not only ha...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L15/34A61L15/28A61L15/44
CPCA61L15/34A61L15/28A61L15/44A61L15/46A61L15/48A61L2300/232A61L2300/404A61L2300/412C08L5/08
Inventor 葛翠兰沈健峰朱培明汪文涛韩韦红
Owner 上海白衣缘生物工程有限公司
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