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Sclerotin repair drug for femoral head necrosis complication caused by hormonotherapy

A technology for necrosis of the femoral head and hormone therapy, which can be used in drug combinations, medical raw materials from fish feed, medical raw materials from ferns/filamentous plants, etc., and can solve problems such as delayed primary disease treatment and femoral head necrosis.

Inactive Publication Date: 2016-06-22
曹兰
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Since the human body is a complex life whole, many autochthonous diseases such as: lupus erythematosus erythematosus nephritis, nephropathy, purpura nephritis and other treatment and relief are often inseparable from glucocorticoids, but long-term use of glucocorticoids will inevitably lead to stock The risk of severe complications such as osteonecrosis, once clinically suspected or confirmed femoral head necrosis, the conventional method is to reduce or stop the use of hormones, the result is to take care of one thing and lose the other. After stopping the use of hormones, although the occurrence of femoral head necrosis can be delayed, But it also delays the treatment of the primary disease

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] Prepare the medicine by preparing the following components by weight: drynaria rhizome 25, dog ridge 12, chuanduan 12, elderberry 25, chuanxiong 12, psoralen 25, Cynomorium 12, Anemarrhena 30, Morinda officinalis 12, hippocampus 6. The content of specific ingredients can be adjusted within the range of plus or minus 10% according to the characteristics of the applicable disease and the source of raw materials.

[0021] The preparation method is as follows:

[0022] Add the above ingredients into 1000 parts by weight of clear water, decoct for 35 minutes, cool naturally to normal temperature, and take its juice as a primary medicinal solution; add the residue of the once medicinal solution into 1000 parts by weight of clear water, decoct for 25 minutes, and naturally cool to The juice is taken at normal temperature as the secondary medicinal liquid; the primary medicinal liquid and the secondary medicinal liquid are mixed to obtain the bone repair medicine for complicat...

example 1

[0029] Example 1: Jiang Moumou, male, 34 years old, from Jinan. Primary nephrotic syndrome, taking prednisone for 3 years, complicated by femoral head necrosis for 2 stages, taking this drug for one month, the pain disappeared, and the CT film showed that the original lesion area of ​​the femoral head was obviously improved, and now it has fully recovered .

example 2

[0030] Example 2: Wang Moumou, female, 14 years old, a student from Binzhou City. Stage 2 membranous nephropathy. The first stage of femoral head necrosis occurred concurrently with prednisone application for half a year, and the symptoms disappeared after adding this drug for one month.

[0031] Example 3: Lan Moumou, male, 27 years old, from Anqiu City. Primary nephrotic syndrome, taking prednisone for one year, complicated by femoral head necrosis in the second stage, using this prescription for three months, the pain and walking disappeared. CT shows: sclerosis of the trabecular bone in the subarterial cavity of the femoral head shrinks.

[0032] Example 4: Qian Mou, male, 19 years old, from Changyi, Shandong. The second stage of membranous nephropathy, taking prednisone for 8 months, complicated by the second stage of femoral head necrosis. After taking this prescription for three months, the pain disappeared and the limp disappeared. CT showed: the sclerosis and nec...

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Abstract

The invention relates to a drug for treating bone diseases, in particular to a sclerotin repair drug for the femoral head necrosis complication caused by hormonotherapy. The sclerotin repair drug is prepared by decocting dipsacus root, fructus psoraleae, rhizoma drynariae, sambucus williamsii, ligusticum wallichii and other traditional Chinese medicinal materials. The drug is small in toxic and side effect and suitable for a patient with femoral head necrosis caused by long-term application of glucocorticoids and a patient with femoral head avascular necrosis caused by long-term drinking or a wound or other disease causes and can improve revascularization and repair of the necrosis portion, treat femoral head necrosis and recover the motion and load bearing function of the femoral head to the maximum. The drug is mainly clinically applied to the patient with femoral head necrosis and osteonecrosis caused by glucocorticoids.

Description

technical field [0001] The invention relates to a traditional Chinese medicine, in particular to a bone repair medicine used for complications of femoral head necrosis caused by hormone therapy. Background technique [0002] Glucocorticoids are commonly used drugs for the treatment of glomerular diseases. Due to long-term use of this drug, some patients may cause femoral head necrosis. Statistical data show that the main causes of femoral head necrosis in China are: glucocorticoids, alcohol consumption, and various traumatic injuries. As we all know, only early treatment of femoral head necrosis will be better. The ultimate goal of early treatment is to improve and increase the blood supply of the femoral head, and promote the resorption of necrotic bone and the re-growth of bone cells in the femoral head necrosis area. The methods and methods commonly used in actual treatment, such as topical application and topical drugs, have no obvious effect. Therefore, choosing tradit...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8964A61P19/08A61P13/12A61K35/60
CPCA61K36/8964A61K9/0095A61K35/60A61K36/11A61K36/126A61K36/185A61K36/236A61K36/35A61K36/487A61K36/746A61K2236/331A61K2236/39A61K2300/00
Inventor 曹兰
Owner 曹兰
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