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Drug for treating femoral head necrosis and promoting bone regeneration

A technology for necrosis of the femoral head and bone, which can be used in drug combinations, bone diseases, pharmaceutical formulations, etc., and can solve problems such as delayed primary disease treatment and femoral head necrosis.

Inactive Publication Date: 2016-05-18
姜桂芹
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Since the human body is a complex life whole, many autochthonous diseases such as: lupus erythematosus erythematosus nephritis, nephropathy, purpura nephritis and other treatment and relief are often inseparable from glucocorticoids, but long-term use of glucocorticoids will inevitably lead to stock The risk of severe complications such as osteonecrosis, once clinically suspected or confirmed femoral head necrosis, the conventional method is to reduce or stop the use of hormones, the result is to take care of one thing and lose the other. After stopping the use of hormones, although the occurrence of femoral head necrosis can be delayed, But it also delays the treatment of the primary disease

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] To prepare the medicine, prepare the following components by weight: Rhizoma Drynariae 20-30, Dog Ridge 10-15, Chuan Duan 10-15, Elderberry 20-30, Rhizoma Chuanxiong 10-15, Psoralen 20-30, Cynomorium 10-12, Anemarrhena 20-30, Morinda officinalis 10-12. The specific component content can be adjusted within the above range according to the characteristics of the applicable disease and the source of the raw material.

[0025] For example, the weight and number ratio of each component can be

[0026] Rhizoma drynaria 30, dog ridge 15, chuanduan 15, elderberry 30, chuanxiong 15, psoralen 30, Cynomorium 12, Anemarrhena 30, Morinda officinalis 12.

[0027] You can also use the following proportions by weight

[0028] Rhizoma drynaria 25, dog ridge 15, chuanduan 10, elderberry 30, chuanxiong 15, psoralen 20, Cynomorium 10, Anemarrhena 20, Morinda officinalis 10, hippocampus 6.

[0029] The preparation method is as follows:

[0030] Add the above ingredients into 1000 parts ...

example 1

[0037] Example 1: Jiang Moumou, male, 34 years old, from Jinan. Primary nephrotic syndrome, taking prednisone for 3 years, complicated by femoral head necrosis for 2 stages, taking this drug for one month, the pain disappeared, and the CT film showed that the original lesion area of ​​the femoral head was obviously improved, and now it has fully recovered .

example 2

[0038] Example 2: Wang Moumou, female, 14 years old, a student from Binzhou City. Stage 2 membranous nephropathy. The first stage of femoral head necrosis occurred concurrently with prednisone application for half a year, and the symptoms disappeared after adding this drug for one month.

[0039] Example 3: Lan Moumou, male, 27 years old, from Anqiu City. Primary nephrotic syndrome, taking prednisone for one year, complicated by femoral head necrosis in the second stage, using this prescription for three months, the pain and walking disappeared. CT shows: sclerosis of the trabecular bone in the subarterial cavity of the femoral head shrinks.

[0040] Example 4: Qian Mou, male, 19 years old, from Changyi, Shandong. The second stage of membranous nephropathy, taking prednisone for 8 months, complicated by the second stage of femoral head necrosis. After taking this prescription for three months, the pain disappeared and the limp disappeared. CT showed: the sclerosis and nec...

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Abstract

The invention relates to a drug for disease treatment, in particular to a drug for treating femoral head necrosis and promoting bone regeneration. The drug is prepared through decoction of multiple traditional Chinese medicines including radix dipsaci asperoidis, fructus psoraleae, rhizoma drynariae, williams elder twig and rhizoma chuanxiong. The toxic and side effects are small. The drug is suitable for patients suffering from femoral head necrosis caused by long-term using of glucocorticoid, and patients suffering from femoral head avascular necrosis caused by long-term drinking or trauma, and can promote revascularization and repair of the necrosis part so as to treat femoral head necrosis and recover the moving and weight bearing functions of the femoral head to the maximum. The drug is mainly clinically applied to patients suffering from femoral head necrosis and osteonecrosis caused by glucocorticoid.

Description

technical field [0001] The invention relates to a traditional Chinese medicine, in particular to a medicine for treating femoral head necrosis and promoting bone regeneration. Background technique [0002] Glucocorticoids are commonly used drugs for the treatment of glomerular diseases. Due to long-term use of this drug, some patients may cause femoral head necrosis. Statistical data show that the main causes of femoral head necrosis in China are: glucocorticoids, alcohol consumption, and various traumatic injuries. As we all know, only early treatment of femoral head necrosis will be better. The ultimate goal of early treatment is to improve and increase the blood supply of the femoral head, and promote the resorption of necrotic bone and the re-growth of bone cells in the femoral head necrosis area. The methods and methods commonly used in actual treatment, such as topical application and topical drugs, have no obvious effect. Therefore, choosing traditional Chinese herba...

Claims

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Application Information

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IPC IPC(8): A61K36/8964A61P19/08A61K35/60
CPCA61K36/126A61K9/0095A61K35/60A61K36/11A61K36/185A61K36/236A61K36/35A61K36/487A61K36/746A61K36/8964A61K2236/331A61K2236/39A61K2300/00
Inventor 姜桂芹
Owner 姜桂芹
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