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A kind of human-like collagen scar repair silicone gel

A technology of human-like collagen and silicone gel, which is applied in the field of scar repair silicone gel and human-like collagen dressing, can solve the problems of unconcerned collagen transdermal absorption speed, and achieve faster transdermal absorption and transdermal absorption rate-enhancing effect

Active Publication Date: 2018-10-12
SHAANXI GIANT BIOTECHNOLOGY CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Unfortunately, the studies so far have only focused on the transdermal absorption rate of collagen, but not on the transdermal absorption rate of collagen.

Method used

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  • A kind of human-like collagen scar repair silicone gel
  • A kind of human-like collagen scar repair silicone gel
  • A kind of human-like collagen scar repair silicone gel

Examples

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preparation example Construction

[0029] There is no special restriction on the preparation method of the human-like collagen silicone gel of the present invention, and the usual preparation method may include:

[0030] Step A: Prepare phase A, the phase A is composed of 2 to 5% by weight of silica, 30 to 50% by weight of cyclopentasiloxane, and the balance of polydimethylsiloxane;

[0031] Step B: Prepare phase B, the phase B is a human-like collagen solution, which contains human-like collagen such that the content of human-like collagen in the human-like collagen silicone gel is 0.01-0.1% by weight, The medium is water such that the water content in the human-like collagen silicone gel is 0.05-1% by weight;

[0032] Step C: Prepare phase C, the phase C is 1-10% by weight of dimethiconol; and

[0033] Step D: Then, use the C phase to disperse the B phase before adding it to the A phase, and stir evenly;

[0034] The total weight of the human-like collagen silicone gel is taken as 100% by weight.

[0035] Here, the hum...

Embodiment 1

[0045] Example 1. Preparation of the human-like collagen silicone gel of the present invention

[0046] Ingredients: silicon dioxide 3%, polydimethylsiloxane 51.45%, cyclopentasiloxane 40%, human-like collagen 0.05%, dimethiconol 5%, water 0.5%.

[0047] Process operation:

[0048] ① Add silicon dioxide first, then slowly add polydimethylsiloxane, after adding, keep stirring until uniform. Then add cyclopentasiloxane, stir while adding, continue stirring after adding until the silica is completely dispersed;

[0049] ②Dissolve human-like collagen in water to obtain a human-like collagen solution. After dispersing the human-like collagen solution in dimethiconol, add silicon dioxide, cyclopentasiloxane and silicon dioxide In the mixing system, continue to stir until uniform.

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Abstract

The invention relates to the field of medical / cosmetic apparatuses, and in particular relates to scar-repairing silica gel containing human-like collagen, wherein the rapid transdermal absorption of the human-like collagen can be promoted. The scar-repairing silica gel can be used for repairing hyperplastic scars or keloids caused by burns, scalds, trauma, operations and the like in the medical / cosmetic field. The scar-repairing silica gel contains the human-like collagen, silica, cyclopentasiloxane, dimethiconol, water and polydimethylsiloxane.

Description

Technical field [0001] The invention relates to a human-like collagen dressing, in particular to a scar repair silicone gel containing human-like collagen, and belongs to the field of beauty / medical equipment. Background technique [0002] Human-like collagen was invented by Professor Fan Daidi of Northwest University in China (see Chinese Patent Application Publication CN1371919A), so it is also called Fan’s Human-like Collagen (Fan’s Human-like Collagen, FHLC). Human-like collagen has a triple-stranded and triple-helical structure. It is a highly biocompatible recombinant collagen and is currently widely used in medical or cosmetic fields. [0003] On the other hand, when collagen dressing products are used to eliminate hyperplastic scars or keloids caused by burns, scalds, trauma, and surgery, the use of collagen dressing products often needs to be done indoors (such as beauty salons, hospitals, etc.) ), as product users hope to be able to complete the use in a short time (the ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K38/39A61L26/00
CPCA61L26/0004A61L26/0019A61L26/0033A61L26/0066A61L2300/252A61L2300/412C08L83/04
Inventor 范代娣马晓轩严建亚王淑英常海燕王小军杨婵媛
Owner SHAANXI GIANT BIOTECHNOLOGY CO LTD
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