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Medicine for treating ventricular premature beat and preparing method

A treatment room and drug technology, applied in the direction of drug combination, pharmaceutical formula, medical preparations containing active ingredients, etc., can solve the problems of low curative effect and long course of treatment, and achieve the effect of improving blood lipids and good curative effect

Active Publication Date: 2016-07-06
SOUTHERN MEDICAL UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although these traditional Chinese medicines and traditional Chinese medicine compositions have certain curative effects in the treatment of premature ventricular contractions, there are problems such as a long course of treatment and low curative effect. Since the above-mentioned medicines are mainly tonic medicines, a considerable number of patients with damp-heat syndrome are prone to discomfort. symptom

Method used

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  • Medicine for treating ventricular premature beat and preparing method
  • Medicine for treating ventricular premature beat and preparing method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0105] Embodiment 1 (granule):

[0106]Weigh 1800g of Danshen, 900g of fried Suanzaoren, 600g of Panax notoginseng, 600g of Coptis chinensis, 600g of Sophora flavescens, 600g of Trichosanthes bark, and 900g of Ophiopogon japonicus. Among them, Salvia miltiorrhiza, Sophora flavescens, and Coptis chinensis were extracted by adding 8 times the amount of 70% ethanol together and heating and refluxing for 3 times, each time for 1.5 hours, collecting and combining the ethanol extracts, filtering, and recovering ethanol from the filtrate under reduced pressure and concentrating to obtain the ethanol extract extract. Set aside; add water and decoct the rest 3 times, boil for 30 minutes after the first boil, fry for 1 hour after the second boil, and fry for 1.5 hours after the third boil. Then combine the decoctions, filter and concentrate the filtrate at 80°C to a clear paste with a relative density of 1.25, mix it with the alcohol extract extract, put it in an oven at 75°C to dry the...

Embodiment 2

[0107] Embodiment 2 (granule)

[0108] Weigh 1760g of Danshen, 969g of fried Suanzaoren, 480g of Panax notoginseng, 529g of Coptis chinensis, 587g of Sophora flavescens, 705g of Trichosanthes bark, and 970g of Ophiopogon japonicus. Among them, Salvia miltiorrhiza, Sophora flavescens, and Coptis chinensis were extracted by adding 8 times the amount of 70% ethanol together and heating and refluxing for 3 times, each time for 1.5 hours, collecting and combining the ethanol extracts, filtering, and recovering ethanol from the filtrate under reduced pressure and concentrating to obtain the ethanol extract extract. Set aside; add water and decoct the rest 3 times, boil for 30 minutes after the first boil, fry for 1 hour after the second boil, and fry for 1.5 hours after the third boil. Then combine the decoctions, filter and concentrate the filtrate at 80°C to a clear paste with a relative density of 1.25, mix it with the alcohol extract extract, put it in an oven at 75°C to dry the...

Embodiment 3

[0109] Embodiment 3 (granule)

[0110] Weigh 2012g of Danshen, 776g of fried Suanzaoren, 633g of Panax notoginseng, 575g of Coptis chinensis, 480g of Sophora flavescens, 575g of Trichosanthes bark, and 949g of Ophiopogon japonicus. Among them, Salvia miltiorrhiza, Sophora flavescens, and Coptis chinensis were extracted by adding 8 times the amount of 70% ethanol together and heating and refluxing for 3 times, each time for 1.5 hours, collecting and combining the ethanol extracts, filtering, and recovering ethanol from the filtrate under reduced pressure and concentrating to obtain the ethanol extract extract. Set aside; add water and decoct the rest 3 times, boil for 30 minutes after the first boil, fry for 1 hour after the second boil, and fry for 1.5 hours after the third boil. Then combine the decoctions, filter and concentrate the filtrate at 80°C to a clear paste with a relative density of 1.25, mix it with the alcohol extract extract, put it in an oven at 75°C to dry the...

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Abstract

The invention discloses a medicine for treating ventricular premature beat.The medicine is prepared from effective ingredients and a medically-acceptable excipient, wherein the effective ingredients are prepared from, by weight, 25-35% of roots of red-rooted salvia, 12-18 parts of semen ziziphi spinosae, 8-12% of panax notoginseng, 8-12% of coptidis rhizoma, 8-12% of radix sophorae flavescentis, 8-12% of pericarpium trichosanthis and 12-18% of radix ophiopogonis.The medicine can be prepared into particles or capsules or tables or other oral preparations, and is clinically verified to have the advantages of being capable of quickly relieving symptoms and short in treatment course.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition prepared from raw materials of Chinese medicinal materials. Background technique [0002] Ventricular premature beats are the most common arrhythmia in clinical practice. Arrhythmia can be caused by various diseases such as coronary heart disease, hypertensive heart disease, heart failure, viral myocarditis, hyperthyroidism, and autonomic dysfunction. Clinically, it often manifests as palpitations and restlessness in the heart, conscious heart beating, panic, involuntary, paroxysmal or persistent, accompanied by chest tightness, upset and irritability, shortness of breath and fatigue, or even chest pain, shortness of breath, cold sweating of limbs , fainting. It belongs to the category of "heart palpitations" in traditional Chinese medicine. With the fast pace of life, high work pressure, strong psychological stress, such ...

Claims

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Application Information

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IPC IPC(8): A61K36/8968A61P9/06
Inventor 贾钰华周凤华孙学刚赵晓山张丽华孙晓敏
Owner SOUTHERN MEDICAL UNIVERSITY
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