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Human body helicobacter pylori infection diagnosing system built on basis of fuel cells and method for detecting content of ammonia in human expiratory gas

A technology of Helicobacter pylori and a fuel cell system, which is applied in the field of medical devices, can solve the problems of radiation hazards to the human body, the rapid urease method is not suitable for re-examination, and patient discomfort, and achieves fast detection speed, reduced patient pain, and specific detection. Effect

Inactive Publication Date: 2016-08-24
长沙三相医疗器械有限公司
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Problems solved by technology

However, the above methods all have their side effects or limitations. For example, gastroscopy biopsy can bring great discomfort to the patient, urea exhalation method has radioactive hazards to the human body, and rapid urease method is not suitable for reexamination, etc.

Method used

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  • Human body helicobacter pylori infection diagnosing system built on basis of fuel cells and method for detecting content of ammonia in human expiratory gas
  • Human body helicobacter pylori infection diagnosing system built on basis of fuel cells and method for detecting content of ammonia in human expiratory gas
  • Human body helicobacter pylori infection diagnosing system built on basis of fuel cells and method for detecting content of ammonia in human expiratory gas

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Experimental program
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Effect test

Embodiment 1

[0043] The time-current response of this method was tested under constant potential for 1ppm and 5ppm ammonia standard gas.

[0044] The specific operation is as follows:

[0045] Set the voltage to be constant at 0. After a period of stable scanning, two concentrations of ammonia standard gas are introduced respectively. The test results are as follows: figure 1 , as ammonia gas is introduced into the system, the current rises sharply.

Embodiment 2

[0047] Test human breath samples.

[0048] The specific operation is as follows:

[0049] 1) Subjects should eat on an empty stomach or three hours in advance.

[0050] 2) Take the next box of unmarked urea reagent in warm boiled water and wait for 30 minutes.

[0051] 3) The gas exhaled by the subject is collected, and the gas is connected to the intake pipe at the same time, so that the gas can completely flow into the fuel cell reaction system.

[0052] 4) Test with the time-current method of Autolab101 electrochemical workstation, and set its voltage as 0V.

[0053] 5) In the above test system, the current signal of the test is as follows figure 2 , the results show that the concentration of ammonia in the exhaled breath of the human body can be detected by this method.

[0054] The above results show that the testing system and method proposed by the present invention are the optimal combination of actual testing, and can simply, accurately and sensitively diagnose v...

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Abstract

The invention discloses a human body helicobacter pylori infection diagnosing system built on the basis of fuel cells and a method for detecting the content of ammonia in human respiratory gas. The human body helicobacter pylori infection diagnosing system comprises oral urea preparations and a fuel cell type ammonia detecting device. The human body helicobacter pylori infection diagnosing system and the method have the advantages that the human expiratory gas is led into the fuel cell type ammonia detecting device after human bodies administer the oral urea preparations, current signals which indicate that oxidation and reduction reaction is carried out on the ammonia in the human respiratory gas in fuel cell systems are detected, accordingly, the content of the ammonia in the human respiratory gas can be quickly and accurately obtained, the helicobacter pylori infection degrees can be sensitively, quickly and specifically detected, toxic and side effects and service limitation can be reduced to a great extent as compared with an existing diagnosing method, and the detection time can be greatly shortened as compared with the exiting diagnosing method.

Description

technical field [0001] The invention relates to a system for diagnosing human Helicobacter pylori infection based on a fuel cell and a method for detecting ammonia content in human exhaled air; in particular, it relates to a urea produced by Helicobacter pylori in the human body after the human body takes ordinary urea granules The principle that enzymes will react with urea to release ammonia gas, and use the ammonia gas detection device designed based on the principle of fuel cells to detect the ammonia content exhaled by the human body to realize the prediction of the infection degree of Helicobacter pylori; it belongs to medical Device technology field. Background technique [0002] Helicobacter pylori (referred to as Hp) is a chronic factor for some diseases such as gastritis, peptic ulcer, lymphoproliferative gastric lymphoma, atrophic gastritis, etc., and these diseases are the most important factors leading to gastric cancer. Studies have shown that pylori Helicobac...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N27/416
CPCG01N27/416
Inventor 纪效波周文强丁莹莹
Owner 长沙三相医疗器械有限公司
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