Novel method for gastric cancer diagnosis

A technology for gastric cancer and analysis methods, which can be applied in the fields of material inspection products, instruments, analysis materials, etc., and can solve the problem that the sugar chain structure does not reveal the accurate scientific basis and so on.
CN106029906AInactive Publication Date: 2016-10-12KOREA ADVANCED INST OF SCI & TECH
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Patent Information

Authority / Receiving Office
CN ยท China
Patent Type
Applications(China)
Current Assignee / Owner
KOREA ADVANCED INST OF SCI & TECH
Publication Date
2016-10-12
Estimated Expiration
Not applicable ยท inactive patent

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Abstract

The present invention relates to a method for gastric cancer diagnosis through the detection of glycan changes, and to a kit for gastric cancer diagnosis. More specifically, based on, among the changes in N-linked glycosylation of the gastric cancer patient-derived haptoglobin, which are detected through lectin and mass spectrometry, the increase in fucosylation, the increases or significant changes in particular glycan structures according to the classification of antennary, or the reduction in high-mannose structure of the N-linked glycan compared with normal persons, the discovered N-glycosylation structures can be favorably used for a method for gastric cancer diagnosis using lectin, as a diagnostic marker, or mass spectrometry, and a kit for diagnosing gastric cancer.
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Description

technical field

[0001] The present invention relates to a novel method for diagnosing gastric cancer by detecting changes in sugar chains, a kit for diagnosing gastric cancer, and a method for detecting changes in sugar chains for providing diagnostic information for gastric cancer, and more particularly to a blood source using lectins and detected by a mass analysis method A method for diagnosing gastric cancer with changes in the N-sugar chain of haptoglobin and a kit for diagnosing gastric cancer. Background technique

[0002] Cancer is the number one cause of death worldwide, and it is also true in Korea. Cancer is formed and developed by genetic and environmental factors, and the number of deaths from cancer and cancer is increasing every year due to changes in dietary life, serious environmental pollution, and severe exposure to environmental and mental stress. Compared with other diseases, cancer is characterized by intractable cure and average low survival rate afte...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
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