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Traditional Chinese medicine decoction for treating narcolepsy caused by internal stagnation of phlegm dampness

A technology for narcolepsy and traditional Chinese medicine decoction, applied in the field of traditional Chinese medicine decoction, can solve the problems of unreasonable prescription compatibility, weakened therapeutic effect, enhanced drug toxicity, etc. Effect

Inactive Publication Date: 2016-12-21
秦月霞
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Common Chinese medicine prescriptions are difficult to take care of comprehensively with only a few herbs, and a variety of drugs must be properly combined to improve efficacy or reduce adverse reactions, so as to adapt to the treatment of complex diseases
In view of the complex interaction of various active ingredients of various Chinese medicinal materials in the body, changes in the pharmacokinetics and pharmacodynamics of various drugs in the body will have various effects on the interaction between drugs. When used in combination, it may not only produce synergistic drug effects, but also may produce antagonistic effects, which will lead to weakening of drug therapeutic effect or treatment failure. Some drugs in combination will also increase drug toxicity and cause adverse reactions; Enhanced, but when the therapeutic effect is excessively enhanced, it will exceed the body's ability to tolerate it, and it can also cause adverse reactions and even endanger patients.
Part of the research is to prepare traditional Chinese medicine prescriptions in order to treat phlegm-dampness internal resistance narcolepsy. The most common problem is that the compatibility of the prescriptions is unreasonable. Efficacy indicators are not applied mechanically to the theory of traditional Chinese medicine, and the flavor of the prescription is added or subtracted at will, resulting in unreasonable prescriptions, which contradict the theory of traditional Chinese medicine

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] Weighing: 9 grams of peony seed oil, 5 grams of iron knife leaves, 6 grams of lampstand leaves, 7 grams of different leaves Patoniae, 8 grams of wild persimmons, 14 grams of Albizia juniper, 13 grams of eggplant, 12 grams of turmeric, stone 10 grams of calamus, 11 grams of tangerine peel, 7 grams of Ma Lian'an, 6 grams of Tongye tea, 5 grams of sugar palm, 4 grams of turmeric, 5 grams of mint, 6 grams of Atractylodes macrocephala, 8 grams of Dendrobium dendrobium, 7 grams of pistachio, 4 grams of saxifrage, 5 grams of Cimicifuga, 6 grams of Bupleurum, and 7 grams of wild cumin.

[0032] The preparation method is as follows: crush the above-mentioned medicinal materials except peony seed oil into coarse powder; decoct twice, add 8 times the amount of water for the first decoction, soak for 2 hours, decoct for 3 hours, filter; add water for the second decoction 6 times the amount, decoct for 2 hours, filter; combine the two decoctions and mix with peony seed oil evenly be...

Embodiment 2

[0050] Weighing: 6 grams of Dengtai leaves, 6 grams of different leaves Patoniae, 5 grams of wild persimmon, 10 grams of Malianan, 6 grams of Tongye tea, 8 grams of sugar palm, 4 grams of turmeric, 4 grams of mint, 6 grams of Atractylodes macrocephala, 8 grams of Dendrobium, 6 grams of pistachio, 4 grams of saxifrage, 4 grams of Cimicifuga, 5 grams of Bupleurum, and 10 grams of wild cumin. The preparation method is the same as in Example 1.

[0051] Among the 10 patients with narcolepsy of the phlegm-damp internal resistance type selected from the traditional Chinese medicine decoction made in Example 2 of the present invention, 8 cases were cured and 2 cases were markedly effective. The cure rate is 80%, and the total effective rate is 100%. The cured patients were followed up for 24 months, and no case of recurrence was found.

Embodiment 3

[0053] Weighing: 6 grams of Dengtai leaves, 6 grams of different leaves Patoniae, 5 grams of wild persimmon, 10 grams of Malianan, 6 grams of Tongye tea, 8 grams of sugar palm, 4 grams of turmeric, 4 grams of mint, 6 grams of Atractylodes macrocephala, 8 grams of Dendrobium, 6 grams of pistachio, 4 grams of saxifrage, 4 grams of Cimicifuga, 5 grams of Bupleurum, and 10 grams of wild cumin. The preparation method is the same as in Example 1.

[0054] Among the 12 patients with narcolepsy of the phlegm-dampness internal resistance type selected from the traditional Chinese medicine decoction made in Example 3 of the present invention, 11 cases were cured and 1 case was markedly effective. The cure rate is 91.6%, and the total effective rate is 100%. The improved and basically cured patients were followed up for 24 months, and no case of recurrence was found.

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PUM

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Abstract

The invention discloses a traditional Chinese medicine decoction for treating narcolepsy caused by internal stagnation of phlegm dampness. The traditional Chinese medicine decoction is prepared from the following traditional Chinese medicinal materials in parts by weight: 9 parts of peony seed oil, 5 parts of folium cassia siamea lam, 6 parts of folium alstoniae scholaris, 7 parts of patrirnia heterophylla, 8 parts of diospyros kaki, 14 parts of cortex albizziae, 13 parts of solanum spirale, 12 parts of radix curcumae, 10 parts of rhizoma acori tatarinowii, 11 parts of pericarpium citri reticulatae, 7 parts of streptocaulongriffithii, 6 parts of herba turpinia arguta, 5 parts of borassus flabellifer, 4 parts of radix curcumae, 5 parts of herba menthae, 6 parts ofrhizoma atractylodis macrocephalae, 8 parts of dendrobium aphyllum, 7 parts of pistaciavera, 4 parts of saxifraga umbellulata var. pectinata, 5 parts of rhizoma cimicifugae, 6 parts of radix bupleuri and 7 parts of lagoecia cuminoides. Clinical experiments prove that the traditional Chinese medicine decoction provided by the invention is conducive to treating narcolepsy caused by internal stagnation of phlegm dampness through reasonable compatibility of the traditional Chinese medicinal materials, can effectively reduce complications and prevent recurrence, and achieves good effects of whole regulation and the long-term efficacy.

Description

technical field [0001] The invention relates to a traditional Chinese medicine decoction, in particular to a traditional Chinese medicine decoction for treating narcolepsy of phlegm-damp internal resistance type. Background technique [0002] Narcolepsy is a syndrome of unclear etiology characterized by abnormal sleep tendencies, including excessive daytime sleepiness, nocturnal restless sleep, and pathological REM sleep. This unexplained sleep disorder is characterized by prolonged periods of decreased vigilance and episodic episodes of irresistible sleep. Narcolepsy of phlegm-dampness internal resistance type is obese, with less body weight, dizzy head, uncomfortable chest and diaphragm, fat tongue with white and greasy coating. Common Chinese medicine prescriptions are difficult to take care of comprehensively with only a few medicines, and a variety of medicines must be properly combined to improve the efficacy or reduce adverse reactions, so as to adapt to the treatmen...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61P25/00
CPCA61K36/9066A61K9/0095A61K36/185A61K36/22A61K36/23A61K36/233A61K36/24A61K36/27A61K36/284A61K36/44A61K36/48A61K36/482A61K36/534A61K36/65A61K36/71A61K36/752A61K36/81A61K36/84A61K36/888A61K36/889A61K36/8984A61K2236/331A61K2236/39A61K2300/00
Inventor 秦月霞其他发明人请求不公开姓名
Owner 秦月霞
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