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Dressing for repairing wound surface and preparing method thereof

A wound and back-up technology, which is applied in the field of wound repair dressing and its preparation, can solve the problems of not easy to peel off, not absorbed by human tissue, and dressing wound adhesion, etc., and achieve the effect of hygroscopicity, good hemostatic effect, and delayed healing

Inactive Publication Date: 2017-02-01
北京东方艾美生物技术股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, if this medical dressing is used for infants, scalds, and burn patients, the dressing is easy to adhere to the wound, is not easy to peel off, and is not absorbed by human tissues.

Method used

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  • Dressing for repairing wound surface and preparing method thereof
  • Dressing for repairing wound surface and preparing method thereof
  • Dressing for repairing wound surface and preparing method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0039] Such as figure 1 As shown, a dressing for repairing wounds includes a non-woven fabric layer 1, a keratin layer 2, a pressure-sensitive adhesive layer 3 and a release paper layer 4, and the keratin layer 2 and the pressure-sensitive adhesive layer 3 are all arranged on the non-woven fabric On the layer 1, the pressure-sensitive adhesive layer 3 is arranged around the periphery of the keratin layer 2 and fixedly connected with the keratin layer 2. The pressure-sensitive adhesive layer 3 can make the connection between the keratin layer 2 and the non-woven fabric layer 1 stronger.

[0040] The release paper layer 4 completely covers the keratin layer 2 and is bonded to the pressure-sensitive adhesive layer 3. The release paper layer 4 is composed of two parts, and the two sides of the two parts close to each other intersect in the middle of the dressing. Folding, that is, overlapping together at the midline of the keratin layer 2, it is more convenient to use, and only ne...

Embodiment 2

[0055] The content of hair keratin in the keratin layer in embodiment 1 is 1.1g / m 2 , the hair keratin is gelled hair keratin, and the preparation method of the gelled hair keratin is as follows:

[0056] Take 200 mg of the high-purity granular hair keratin obtained in Example 1 of the present invention and add 5 ml of water, mix well, place in an incubator and incubate at 37°C until a relatively uniform color and shape appear; Sterilized to obtain gelled hair keratin with a concentration of 4%. Figure 7 It is the property of gelled hair keratin at a concentration of 4%.

[0057] It should be noted that the granular hair keratin used in this example can also be prepared in Example 2.

Embodiment 3

[0059] The content of hair keratin in the keratin layer in embodiment 1 is 1.2g / m 2 , the hair keratin is gelled hair keratin, and the preparation method of the gelled hair keratin is as follows:

[0060] Take the high-purity granular hair keratin 125 mg obtained in Example 2 of the present invention and add 5 ml of water, mix well, place it in an incubator and incubate until it presents a relatively uniform color and character; sterilize to obtain Gelatinized hair keratin, its concentration is 2.5%, its property is than Figure 7 The character of the gelled hair keratin is thinner.

[0061] It should be noted that the granular hair keratin used in this example can also be prepared in Example 1.

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Abstract

The invention relates to a dressing for repairing a wound surface and a preparing method thereof. The dressing comprises a non-woven fabric layer, a keratin layer and a pressure-sensitive adhesive layer, the keratin layer and the pressure-sensitive adhesive layer are both arranged on the non-woven fabric layer, and the pressure-sensitive adhesive layer is arranged on the periphery of the keratin layer and fixedly connected with the keratin layer. Keratin is arranged in the keratin layer and is hair keratin, and the hair keratin is any one of granular hair keratin and gelation hair keratin. The dressing and the preparing method have the advantages that the hemostatic effect is good, and repairing of the wound surface can be effectively accelerated; bacterial infection can be effectively prevented; good biocompatibility is achieved; oozing of the wound surface is controlled and absorbed; air permeability is high; regenerated tissue is protected; toxic and side effects are avoided, and irritability is avoided; utilization is convenient.

Description

technical field [0001] The invention relates to a dressing, in particular to a dressing for repairing wounds and a preparation method thereof. Background technique [0002] In the prior art, relevant medical dressings are usually composed of non-woven fabrics, absorbent paper, wadding, and leak-proof membranes. This kind of paper-type medical dressings has a large amount of liquid absorption, does not change shape after absorbing liquids, and does not break or break. However, if this medical dressing is used for infants, scalds, and burn patients, the dressing is easy to adhere to the wound, is not easy to peel off, and is not absorbed by human tissue. Therefore, the applicant regards the construction of a matrix and scaffold system that simulates body tissues and functions as the focus of scientific research, and rebuilds or restores the skin barrier as the ultimate goal of wound treatment. Biological dressings are currently the most important wound coverings. An ideal wou...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L15/32A61L15/42A61L15/64A61F13/02
CPCA61L15/32A61L15/42A61L15/64A61F13/00051A61F13/00987A61F13/02A61F2013/00089A61L2400/04A61F13/01042A61F13/01034A61F13/01029C08L89/04
Inventor 张飞章庆国张娇郑秋
Owner 北京东方艾美生物技术股份有限公司
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