The invention discloses application of oridonin in preparation of an external preparation for treating
skin scald, and belongs to the technical field of medicines. It is found for the first time that oridonin can effectively relieve the injury degree of
skin scald and promote
wound healing, the content of oridonin in the external preparation is 0.1-1% w / w, the
dosage form can be selected from oil-in-water
emulsion, plaster or hydrogel, and after the oridonin is matched with auxiliary materials such as a
gel matrix and a transdermal
enhancer, animal experiments prove that the oridonin can be used for preparing the external preparation. The 0.1% oridonin external preparation and the 1% oridonin external preparation can improve the symptoms of mice with
scalded skin and promote
wound healing, and the
treatment effect of the oridonin external preparation is superior to that of asiaticoside ointment. According to the invention, the medicinal application of oridonin is expanded, a new effective
medicine choice is provided for treating
skin scald, and the oridonin has good clinical application value and popularization prospect.