81results about How to "Delayed healing" patented technology

A system and method are disclosed for removing a uterus using a fluid enclosure inserted in the peritoneal cavity of a patient so as to enclose the uterus. The fluid enclosure includes a distal open end surrounded by an adjustable loop, that can be tightened, a first proximal opening for inserting an electrosurgical instrument into the fluid enclosure, and a second proximal opening for inserting an endoscope. The loop is either a resilient band extending around the edge of the distal open end or a drawstring type of arrangement that can be tightened and released. The fluid enclosure is partially inserted into the peritoneal cavity of a patient in a deflated condition and then manipulated within the peritoneal cavity over the body and fundus of the uterus to the level of the uterocervical junction. The loop is tightened around the uterocervical junction, after which the enclosure is inflated using a conductive fluid. The loop forms a pressure seal against the uterocervical junction to contain the conductive fluid used to fill the fluid enclosure. Endoscopically inserted into the fluid enclosure is an electrosurgical instrument that is manipulated to vaporize and morcellate the fundus and body of the uterus. The fundus and body tissue that is vaporized and morcellated is then removed from the fluid enclosure through the shaft of the instrument, which includes a hollow interior that is connected to a suction pump The fundus and body are removed after the uterus has been disconnected from the tissue surrounding uterus.

The invention relates to a modified starch material for biocompatible hemostasis, biocompatible anti-adhesion, tissue healing promotion, absorbable surgery sealing and tissue adhesion. The invention applies biocompatible modified starch to animal tissues, wherein the modified starch material has the molecular weight of more than 15,000 daltons, and the particle diameter of between 1 and 1,000 mu m. The modified starch hemostatic material has stypticity, reduces hemorrhage, blood oozing and tissue fluid oozing of wounds, maintains relative moistening or drying of wound surfaces or the wounds, inhibits bacterium growth and inflammation reaction, and contributes to locally diminish inflammation of the wounds and relieve pain of patients. Moreover, the modified starch material can wash local parts after operation is over and remove redundant modified starch which does not participate in hemostasis, and can easily remove haemostatic under the condition of debridement treatment after self-help and first-aid treatment of war wounds; and hemostatic materials with a small amount of modified starch can be absorbed by the body, so that the pain of tearing of gauzes and bandages on people is avoided.

A non-invasive tissue oxygenation system for accelerating the healing of damaged tissue and to promote tissue viability is disclosed herein. The system is comprised of a lightweight portable electrochemical oxygen concentrator, a power management system, microprocessors, memory, a pressure sensing system, a temperature monitoring system, oxygen flow rate monitoring and control system, a display screen and key pad navigation controls as a means of providing continuous variably controlled low dosages of oxygen to a wound site and monitoring the healing process. A kink resistant oxygen delivery tubing, whereby the proximal end is removably connected to the device and the distal end with holes or a flexible, flat, oxygen-permeable tape is positioned on the wound bed as a means of applying oxygen to the wound site. The distal end of the tube is in communication with the electrochemical oxygen concentrator and wound monitoring system to communicate temperature and oxygen partial pressure information. A moisture absorbent dressing is positioned over the distal end of the tubing on the wound site and a reduced moisture vapor permeable dressing system is positioned whereby covering the moisture absorbent dressing, distal end of tubing and wound site creating a restricted airflow enclosure. The restricted airflow enclosure allows the out-of-the-way control and display unit to provide a controlled hyperoxia and hypoxia wound site for accelerated wound healing.

Topical exposure of nitric oxide gas to wounds such as chronic non-healing wounds may be beneficial in promoting healing of the wound and in preparing the wound bed for further treatment and recovery. Nitric oxide gas may be used, for example, to reduce the microbial infection and burden on these wounds, manage exudate secretion by reducing inflammation, upregulate expression of endogenous collagenase to locally debride the wound, and regulate the formation of collagen. High concentration of nitric oxide ranging from about 160 to 400 ppm may be used without inducing toxicity in the healthy cells around a wound site. Additionally, exposure to the high concentration for a first treatment period reduces the microbial burden and inflammation at the wound site and increase collagenase expression to debride necrotic tissue at the wound site. After a first treatment period with high concentration of nitric oxide, a second treatment period at a lower concentration of nitric oxide preferably ranging from about 5-20 ppm may to provided to restore the balance of nitric oxide and induce collagen expression to aid in the closure of the wound.

The invention relates to a biocompatible pre-gelatinized modified starch. The water absorbency is not less than one time, and the biocompatible pre-gelatinized modified starch is taken as biocompatible hemostatic material, biocompatible anti-blocking material, biocompatible tissue-healing promoting material, biocompatible surgical sealant or biocompatible wound closure tissue glue. The invention has the advantages that the biocompatible pre-gelatinized modified starch is directly acted on the wounded area with blood for immediately stopping bleeding, has obviously increased water absorbency and speed of water absorption and greater viscosity and stickiness and further plays the role in preventing the tissue and the blood vessel from being damaged during the process of stopping bleeding; the modified starch is easy to swell or dissolve in water, and is washed by normal saline after the bleeding stopping so as to reduce the residual in the body, to be favorable for wound healing and to avoid the pain due to tearing the gauze and the bandage out; the pre-gelatinized modified starch has the actions of bacterial resistance and anti-inflammatory; and the pre-gelatinized modified starch is stable, not easy to decompose, long in guarantee period, convenient for storage, resistant at high pressure and low pressure, resistant at high temperature and low temperature and not easy to change the physicochemical characteristics.

A wound treatment system includes a housing. A processor is located in the housing. A pressure monitoring system is coupled to the processor. A power delivery system is located in the housing and coupled to the processor. An oxygen concentrator is located in the housing and coupled to the power delivery system. The oxygen concentrator includes a plurality of oxygen outlets. The processor is configured to receive pressure information from the pressure monitoring system that is indicative of a pressure in a restricted airflow enclosure provided by a dressing and located adjacent a wound site; and use the pressure information to control the power provided from the power delivery system to the oxygen concentrator in order to control an oxygen flow created by the oxygen concentrator and provided through one of the plurality of oxygen outlets to the restricted airflow enclosure.

Water-soluble polymeric adhesive compositions and their use as delivery vehicles for carrying therapeutic agents on implantable devices, such as vascular grafts, are disclosed. Use of drug-coated vascular grafts is demonstrated for delivery of the therapeutic agents in vivo, thereby inhibiting restenosis or neointimal hyperplasia of the vascular graft and inhibiting infection at the vascular graft site. Methods of forming the adhesive and making the coated vascular grafts are also disclosed.

The invention provides amnion eye drops for curing cornea alkali burn and a preparation method thereof. The preparation method comprises the steps of: taking amnion homogenate supernate as main activeconstituent; and adding with trehalose, hyaluronic acid or salt thereof, heparin or salt thereof, sodium chloride, benzalkonium bromide, vitamin, etc. The eye drops belongs to an ophthalmology drug delivery system, has a good lubrication function, and can provide a conglutination-resistant surface; and the drug delivery system is added with the other pharmacological active constituents, thereby being capable of increasing the viscocity of medical liquid, prolonging the residence time of the drug in eye surface, improving the bioavailability of the drug, reducing the side effect of the drug, reducing the drug irritation, and having a slow release effect. The amnion eye drops is an effective ophthalmology new drug, and has good clinic application foreground.

The invention relates to an antimicrobial and preferably non-cytotoxic composite material and to various uses of said composite material.

The invention provides a method for building a vascularized tissue engineering periosteum. The method is characterized by comprising the following steps: 1, preparing a macromolecular micro/nano-fibermembrane by an electrostatic spinning method; 2, inoculating seed cells to the nano-fiber membrane, performing cultivation in vitro and performing directional induction for a period of time; 3, implanting a seed cell/nano-fiber membrane composite body subjected for in-vitro directional induction for a period of time in vivo, performing in-vivo vascularization for a period of time and then takingout to obtain the tissue engineering periosteum. By the method, the rejection reaction of an autologous tissue can be effectively reduced and the vascularization degree of the tissue engineering periosteum can be greatly increased; furthermore, the tissue engineering periosteum is vascularize in vivo in advance, so that the integration time of a blood vessel at the defect position and a blood vessel of the implanted tissue engineering periosteum can be shortened, the healing process of the bone defect is shortened, and the method has a very wide application prospect in the fields of wound healing and tissue engineering.

The present disclosure comprises antimicrobial compositions and devices comprising silver compounds that resist heat and light discoloration. In one aspect, the said compounds comprise silver and at least one s-triazine ring or moiety. In another aspect, the antimicrobial compositions are hydrogels that are effective against broad spectrum of common pathogens including MRSA and VRE and are suitable for treating human or animal wounds and burns. The methods of the present disclosure comprise treating medical and non-medical devices and articles with compositions comprising the silver compounds to impart antimicrobial property.

In an embodiment of the present invention, a nutraceutical formula comprising a combination of chromium, zinc, berry extract, Polygonum cuspidatum extract, aloe vera, chlorophyll and L-arginine combined synergistically to reduce inflammation in mammals suffering from diabetes. In another embodiment of the present invention, a nutraceutical formula comprising a of zinc, chromium, berry extract, Polygonum cuspidatum extract, aloe vera, chlorophyll and L-arginine combined synergistically to enhance wound healing in mammals suffering from diabetes. In an alternative embodiment of the present invention, a nutraceutical formula comprising a of zinc, chromium, berry extract, Polygonum cuspidatum extractive, aloe vera, chlorophyll and L-arginine combined synergistically to reduce inflammation in mammals not suffering from diabetes. In another embodiment of the present invention, a nutraceutical formula comprising a combination of zinc, chromium, berry extract, Polygonum cuspidatum extractive, aloe vera, chlorophyll, and L-arginine combined synergistically to enhance wound healing in mammals not suffering from diabetes.

The invention relates to the technical field of sweet osmanthus grafting and seedling breeding, in particular to a sweet osmanthus grafting and seedling breeding method. Sweet osmanthus seedlings subjected to layering serve as stock, leaf bud seedlings obtained after leaf buds are subjected to cuttage and seedling breeding serve as scions, processing and control are conducted in the breeding process of the scions and the stock, so that the content of harmless bacteria on the stock and the scions is small, influences of the harmful bacteria on the cut environment in the grafting process are avoided, and affinity of the stock and scions is improved. The sweet osmanthus seedlings subjected to layering serve as the stock, and the leaf bud seedlings obtained after the leaf buds are bred serve as the scions so that after the stock and the scions are grafted, regeneration can be conducted quickly, the speed of healing of the stock and the scions is increased, and the survival rate is increased.

An acetabulum posterior wall angle locking anatomic bone plate pertains to the technical field of surgical medical devices. The invention provides the acetabulum posterior wall angle locking anatomic bone plate which has small surgical incision, safe and reliable fixation and is conductive to the healing of fracture. The invention includes a plate body which is provided with screw holes, the screw holes are two rows of oblique holes, which are respectively arranged along one side of the plate body which is opposite to the edge of the acetabulum and the opposite side, the oblique included angle Alpha of the central line of the screw holes which are arranged at the one side of the plate body which is opposite to the edge of the acetabulum and the plate surface is 30 degrees to 45 degrees, and the oblique included angle Beta of the central line of the screw holes at the opposite side and the plate surface is 30 degrees to 60 degrees. The invention can make use of the self-shape to ensure the fixation of fracture to be most close to the normal structure after the reduction and fixation of the fracture. The invention has the integrity and the stability which are not possessed by the combined usage of a plurality of bone plates. The invention can reduce surgical incision, reduce the dissection of soft tissues, have less oppression on the periosteum and be more conductive to the healing of fracture. The placement and the removal are easy, and the cost is low. When a screw is screwed, the rod part of the screw can accurately avoid the acetabulum.

Preparation of nano chitosan in the invention almost has no chemical reaction, chitosan is mainly dissolved and dispersed, and chitosan is not dissolved in a sodium hydroxide solution, so that chitosan particles are separated out. Meanwhile, preparation conditions are mild, the safety is high, and preparation raw materials are common and nontoxic. The obtained nano chitosan is an ideal raw material for preparing artificial skin, the prepared artificial skin is soft in texture and is comfortable, the laminating performance between the prepared artificial skin and a wound surface is good, and the prepared artificial skin is breathable, can absorb water, has antibacterial and anti-inflammatory effects, and has the functions of stopping pain, arresting bleeding and promoting wound healing. Along with the healing of the wound of a patient and the growth of the skin of the patient, the chitosan artificial skin can be automatically dissolved and absorbed by the body, scraps cannot be left so as to avoid the delay of wound healing, and skin regeneration can be promoted. Moreover, the operation is simple, the safety is improved, and preparation processes are simplified. Required instruments are relatively common so as to be favorable for reducing the cost, and thus the nano chitosan has important application value in the field of artificial skin.

In an embodiment of the present invention, a nutraceutical formula comprising a combination of two or more substances from the group: berry extract, chromium, zinc, trans-resveratrol, l-arginine, chlorophyll, vitamin C and aloe vera combined synergistically to reduce inflammation in mammals suffering from diabetes. In another embodiment of the present invention, a nutraceutical formula comprising a combination of two or more substances from the group: berry extract, chromium, zinc, fr-απs-resveratrol, l-arginine, chlorophyll, vitamin C and aloe vera combined synergistically to enhance wound healing in mammals suffering from diabetes. In an alternative embodiment of the present invention, a nutraceutical formula comprising a combination of two or more substances from the group: berry extract, chromium, zinc, trans-resveratrol, l-arginine, chlorophyll, vitamin C and aloe vera combined synergistically to reduce inflammation in mammals not suffering from diabetes. In another embodiment of the present invention, a nutraceutical formula comprising a combination of two or more substances from the group: berry extract, chromium, zinc, trans-resveratrol, l-arginine, chlorophyll, vitamin C and aloe vera, combined synergistically to enhance wound healing in mammals not suffering from diabetes.

The invention relates to a dressing for repairing a wound surface and a preparing method thereof. The dressing comprises a non-woven fabric layer, a keratin layer and a pressure-sensitive adhesive layer, the keratin layer and the pressure-sensitive adhesive layer are both arranged on the non-woven fabric layer, and the pressure-sensitive adhesive layer is arranged on the periphery of the keratin layer and fixedly connected with the keratin layer. Keratin is arranged in the keratin layer and is hair keratin, and the hair keratin is any one of granular hair keratin and gelation hair keratin. The dressing and the preparing method have the advantages that the hemostatic effect is good, and repairing of the wound surface can be effectively accelerated; bacterial infection can be effectively prevented; good biocompatibility is achieved; oozing of the wound surface is controlled and absorbed; air permeability is high; regenerated tissue is protected; toxic and side effects are avoided, and irritability is avoided; utilization is convenient.

The invention relates to a preparation method for a hair keratin-cell tissue composite engineered dressing. The preparation method comprises the following steps: preparation of hair keratin; preparation of a cell suspension; and preparation of the dressing. The engineered dressing provided by the invention is a wound covering material with excellent effect, is capable of efficiently preventing bacterial infection, accelerating wound healing and has the advantages of good biocompatibility, capacity of controlling and absorbing exudates from wounds and allowing permeation of gas and water vapor, good air permeability, protection effect on newborn tissue, no toxic and side effect, etc. More importantly, the engineered dressing can be dissolved and absorbed by the body, so considerable bleeding and pains of patients during removing of the engineered dressing are avoided, no scrap is left to delay wound healing, and an environment beneficial for wound healing is provided for promotion of skin regeneration.