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Application of oridonin in preparation of external preparation for treating skin scald

PendingCN122075470AEnrich clinical treatment methodsincrease damageOrganic active ingredientsAerosol deliveryWound healingPharmaceutical drug
The invention discloses application of oridonin in preparation of an external preparation for treating skin scald, and belongs to the technical field of medicines. It is found for the first time that oridonin can effectively relieve the injury degree of skin scald and promote wound healing, the content of oridonin in the external preparation is 0.1-1% w / w, the dosage form can be selected from oil-in-water emulsion, plaster or hydrogel, and after the oridonin is matched with auxiliary materials such as a gel matrix and a transdermal enhancer, animal experiments prove that the oridonin can be used for preparing the external preparation. The 0.1% oridonin external preparation and the 1% oridonin external preparation can improve the symptoms of mice with scalded skin and promote wound healing, and the treatment effect of the oridonin external preparation is superior to that of asiaticoside ointment. According to the invention, the medicinal application of oridonin is expanded, a new effective medicine choice is provided for treating skin scald, and the oridonin has good clinical application value and popularization prospect.
Owner:SOUTHERN MEDICAL UNIVERSITY