Antimicrobial composite material

An anti-microbial and biocide technology, applied in metal material coating technology, biocides, animal repellants, etc., can solve the problems of large amount of reagents, cannot be used in medical products, cannot exclude cytotoxicity, etc. The effect of durability

Active Publication Date: 2007-01-10
BIO GATE AG +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the amount of reagent released is too high to rule out a cytotoxic effect
Coatings such as those described in said do

Method used

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  • Antimicrobial composite material
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Examples

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Example Embodiment

[0048] Example 1: Preparation of the coating material of the present invention

[0049] In the first coating step, the solid substrate to be coated with the antimicrobial and non-cytotoxic coating material of the present invention is coated with porous nanoscale silver. This is achieved by vaporizing metallic silver in an inert gas atmosphere, such as argon, at a working pressure of about 10 mbar. A silver coating (biocide layer) is produced on this substrate, said coating containing single silver particles or chains of silver particles. The average particle size of the silver particles is 10-20 nm. The thickness of the silver coating (biocide layer) is about 20 nm.

[0050] In the second coating step, a plasma polymer layer containing hexamethyldisilicate (HMDSO) as a precursor is coated. It is made of 95% O under the working pressure of 0.07 mbar 2 A working gas composed of 5% HMDSO is used for plasma polymerization. After plasma polymerization was performed for 45 seconds under...

Example Embodiment

[0052] Example 2: Preparation of the coating material according to the present invention using an adhesion-promoting layer

[0053] In the first step, the substrate to be coated with the coating material of the present invention is coated with a titanium dioxide film by plasma polymerization. The precursor used was tetraisopropyl titanium oxide mixed with oxygen. The polymerization time is 5 minutes. Form 25nm thick TiO with good adhesion 2 membrane.

[0054] In the second coating step, in an ultra-high vacuum, a thin metallic silver layer is deposited on the TiO 2 膜上。 On the membrane. During the deposition process, the process pressure is 10 -4 millibar. Evaporate so that a 10-20nm thick silver layer (biocide layer) is deposited on the TiO 2 膜上。 On the membrane.

[0055] In the third coating step, a plasma polymer film (transport control layer) is coated on the silver layer. The plasma polymerization was carried out as described in Example 1. A highly hydrophilic plasma polymer l...

Example Embodiment

[0057] Example 3: Coating the transmission control layer on the biocidal solid

[0058] Using the plasma polymerization method described in Example 1, a plasma polymer film was deposited on the copper solid layer as a transmission control layer. Compared with Example 1, the plasma coating process was performed for 450 seconds. The thickness of the transmission control layer thus prepared was 100 nm. To obtain the coating material according to the present invention, the biocide layer is an initial layer of solid copper.

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Abstract

The invention relates to an antimicrobial and preferably non-cytotoxic composite material and to various uses of said composite material.

Description

technical field [0001] The invention relates to an antimicrobial and preferably non-cytotoxic coating material and to the use of said coating material. Background technique [0002] There is a continuing need in many fields to control the colonization, reproduction and survival of microorganisms, especially prokaryontae and fungi. In particular, it is often desirable to limit the concentration of microorganisms on a particular area, or to completely free the area from microorganisms, or in some cases to completely free the area from a particular type or species of microorganisms. The aim is to achieve this in the broadest sense in the fields of medicine, medical technology and hygiene technology. For this purpose, antimicrobial materials and coatings, such as silver-coated wires for surgical use (see S. Silver, FEMS Microbiology Reviews (2003): pp.341-353) or copper-containing wires, are commonly used, for example, in the field of medical and hygiene products. Antifouling ...

Claims

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Application Information

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IPC IPC(8): A01N25/26A01N25/32A01N59/16A61L15/18A61L15/46A61L27/30A61L27/54A61L29/10A61L29/16A61L31/08A61L31/16C23C14/00C23C16/00A01N25/34A01N59/20B65D81/24B65D81/28
CPCA61L27/306A61L29/106A61L31/088A01N25/34A01N59/20A01N59/16A01N25/10A01N25/32A01N2300/00A01N25/26A61L15/18A61L15/26A61L15/44A61L27/34A61L27/54A61L29/085A61L29/16A61L31/10A61L31/16A61L2300/102A61L2300/104A61L2300/404A61L2420/02A61L2420/08
Inventor 迈克尔·瓦格纳克劳斯·迪特尔·维辛迪尔克·扎尔茨彼得·施泰因吕克
Owner BIO GATE AG
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