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Collagen gel with congelation state

A technology of collagen and state, which is applied in the field of functional application development of biomaterial collagen, can solve problems such as side effect research, no type selection or modification, and provide beneficial technical guidance, etc., to achieve increased skin affinity, excellent skin permeability, Effects from a wide range of sources

Inactive Publication Date: 2017-02-22
BEIJING PAISHENG BIOTECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] In the prior art, especially in cosmetic products, although the use of collagen is involved, there is no research on possible side effects, and there is no useful technical guidance on type selection or modification or atelopeptide.

Method used

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Embodiment Construction

[0023] The present invention is described below in conjunction with embodiment.

[0024] Collagen, also known as collagen, is a helical fibrous protein twisted by three peptide chains. After the collagen is hydrolyzed, the triple helix structure of the collagen is completely loosened and becomes 3 free peptide chains. The non-helical telopeptides of the collagen peptide chain include the N-terminal telopeptide and the C-terminal telopeptide, where the C-terminal represents the carboxyl terminal and the N-terminal represents the amino-terminal. In the application technology of collagen, some remove the telopeptide of collagen, that is, atelopeptide, while others retain the telopeptide of collagen. There are many types of collagen, such as I, II, III, V, IX, XI, XII, and VIII. In the embodiment of the present invention, type I collagen and / or type I collagen hydrolyzate; atelopeptide type I collagen and / or atelopeptide type I collagen hydrolyzate are selected.

[0025] Type Ⅰ...

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PUM

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Abstract

The invention provides collagen gel with jelly state. The jelly state refers to that gel becomes jelly and is in a semisolid form at a lower temperature, such as 0-20 DEG C. Type I collagen is adopted and undergoes telopeptide removal treatment, so immunogenic reaction (causing skin allergy) caused by the telopeptide-containing collagen can be avoided when the gel is used on human bodies.

Description

technical field [0001] The present invention relates to the functional application development technology of biological material collagen, especially a kind of collagen dew in a frozen state. When frozen, it presents a semi-solid form; the collagen adopts type I collagen and is treated with atelopeptide, so that the immunogenic reaction caused by the telopeptide-containing collagen can be avoided when used on the human body. Background technique [0002] Collagen is the main component of the extracellular matrix and the most abundant structural protein in the human body, also known as collagen, accounting for about 25% to 35% of the total protein in the body, and is the main component of the skin. The content of collagen in the dermis of babies is as high as 80%, so it is delicate, moist, delicate and flawless, and full of elasticity; as the age increases, collagen begins to lose at the age of 18-22, and small pores appear on the cheeks; 25-year-old women The collagen conte...

Claims

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Application Information

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IPC IPC(8): A61K8/65A61K8/04A61K38/01A61Q19/00A61Q19/08A61P17/00A61P17/18
CPCA61K8/65A61K8/042A61K38/014A61Q19/00A61Q19/08
Inventor 张自强李海涛徐荣荣
Owner BEIJING PAISHENG BIOTECH CO LTD
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