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Surgical operation suturing material and preparation method thereof

A surgical and raw material technology, applied in the field of medical materials, can solve the problems of hindering wound healing, low biocompatibility, low tensile strength of sutures, etc., and achieve the effects of easy processing, easy knotting, and promoting healing.

Inactive Publication Date: 2017-02-22
ZHENGZHOU YUANRAN BIOLOGY TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] It can be seen that the quality requirements of sutures are very high, but most of the current sutures have low biocompatibility, low tensile strength in the tissue, and hinder normal wound healing. It is urgent to develop a new type of surgical suture. materials

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] A material for surgical suture, in parts by weight, the raw materials are: 15 parts of polyglycolic acid, 5 parts of bone collagen, 11 parts of polylactic acid, 0.5 part of tryptophan, 0.4 part of fish collagen, 2 parts of achyranthes bidentata, 0.01 part of vitamin.

[0021] A preparation method of a surgical suture material, the specific steps are:

[0022] (1) First, mix polyglycolic acid, polylactic acid and tryptophan, then put them into the reactor, and react under 2MPa pressure and nitrogen protection. After the reaction, melt spinning is carried out, and the spinning mixture is obtained after cooling. ;

[0023] (2) Then, mix the spinning mixture with bone collagen, fish collagen, achyranthes bidentata, and nisin, control the water content at 45%, and then use ultrasonic oscillation treatment, the power of ultrasonic oscillation treatment is 120W, and the time is 13 Minutes, placed in 4 ° C temperature and low temperature drying, to obtain surgical suture mate...

Embodiment 2

[0025] A material for surgical suture, in parts by weight, the raw materials are: 18 parts of polyglycolic acid, 6 parts of bone collagen, 12 parts of polylactic acid, 0.6 part of tryptophan, 0.5 part of fish collagen, 2 parts of achyranthes bidentata, 0.02 parts of vitamins.

[0026] A preparation method of a surgical suture material, the specific steps are:

[0027] (1) First, mix polyglycolic acid, polylactic acid and tryptophan, then put them into the reactor, and react under 2MPa pressure and nitrogen protection. After the reaction, melt spinning is carried out, and the spinning mixture is obtained after cooling. ;

[0028] (2) Then, mix the spinning mixture with bone collagen, fish collagen, achyranthes bidentata, and nisin, control the water content at 45%, and then use ultrasonic oscillation treatment, the power of ultrasonic oscillation treatment is 120W, and the time is 13 Minutes, placed in 4 ° C temperature and low temperature drying, to obtain surgical suture ma...

Embodiment 3

[0030] A material for surgical suture, in parts by weight, the raw materials are: 20 parts of polyglycolic acid, 7 parts of bone collagen, 13 parts of polylactic acid, 0.7 part of tryptophan, 0.6 part of fish collagen, 3 parts of achyranthes bidentata, 0.03 parts of vitamins.

[0031] A preparation method of a surgical suture material, the specific steps are:

[0032] (1) First, mix polyglycolic acid, polylactic acid and tryptophan, then put them into the reactor, and react under 2MPa pressure and nitrogen protection. After the reaction, melt spinning is carried out, and the spinning mixture is obtained after cooling. ;

[0033] (2) Then, mix the spinning mixture with bone collagen, fish collagen, achyranthes bidentata, and nisin, control the water content at 48%, and then use ultrasonic oscillation treatment, the power of ultrasonic oscillation treatment is 120W, and the time is 13 Minutes, placed in 4 ° C temperature and low temperature drying, to obtain surgical suture ma...

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Abstract

The invention discloses a surgical operation suturing material and a preparation method thereof. The surgical operation suturing material comprises the following raw materials in parts by weight: 15-23 parts of polyglycolic acid, 5-8 parts of ossein, 11-14 parts of polylactic acid, 0.5-0.9 part of tryptophan, 0.4-0.8 part of fish collagen protein, 2-4 parts of radix achyranthis bidentatae and 0.01-0.05 part of nisin. The surgical operation suturing material disclosed by the invention is free of toxin, harm and accumulation, easy to process and mold, high in strength, easy to tie and good in properties such as flexibility and sterilization and disinfection resistance, capable of promoting heal of a wound, and can be completely absorbed and degraded in biological tissue within 15-25 days.

Description

technical field [0001] The invention relates to the field of medical materials, in particular to a surgical suture material and a preparation method thereof. Background technique [0002] Medical sutures are common biocompatible textiles that are widely used in various surgical operations to suture wounds, connect tissues and ligate blood vessels. As early as 3500 BC, the ancient Egyptians had used cotton fibers and horsehair to suture wounds, and ancient Chinese history books also recorded that hemp fibers were used as sutures. With the development of polymers and their fibers, there are more and more varieties of medical sutures. [0003] There are many types of sutures, including absorbable and nonabsorbable sutures. Many common natural and synthetic textile fibers have been successfully used as medical non-absorbable sutures. The types of non-absorbable sutures that have been developed include cotton, silk, hemp, polyamide, polyester, polypropylene and metal sutures. ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L17/12A61L17/08A61L17/06
CPCA61L17/12A61L17/005A61L17/06A61L17/08A61L2300/252A61L2300/30
Inventor 刘东东
Owner ZHENGZHOU YUANRAN BIOLOGY TECH CO LTD
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